Works Published in 2015
Displaying works 1 - 20 of 45 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2015 journal article
Genome-wide identification of CCA1 targets uncovers an expanded clock network in Arabidopsis.
Proceedings of the National Academy of Sciences of the United States of America.
author keywords: genome-wide; circadian clock; clock-controlled outputs; transcriptional regulation
MeSH headings : Arabidopsis / genetics; Arabidopsis Proteins / genetics; Genome, Plant; Transcription Factors / genetics; Transcriptome
TL;DR:
A genome-wide characterization of the direct targets of a key clock component in Arabidopsis revealed several CCA1 targets that do not cycle in either LL or LD conditions, suggesting that C CA1 plays an important role in regulating a large subset of the rhythmic transcriptome.
(via Semantic Scholar)
www.pnas.org (publisher PDF)
Source: ORCID
Added: January 25, 2021
2015 journal article
Regulation of the Arabidopsis CBF regulon by a complex low-temperature regulatory network.
The Plant Journal : for Cell and Molecular Biology.
author keywords: CBF regulatory pathway; low-temperature regulatory network; freezing tolerance; Arabidopsis thaliana
MeSH headings : Arabidopsis / genetics; Arabidopsis / metabolism; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Cold Temperature; Gene Expression Regulation, Plant; Regulon / genetics
TL;DR:
The results indicate that cold regulation of the CBF regulon involves extensive co-regulation by other first-wave transcription factors; that the low-temperature regulatory network beyond theCBF pathway is complex and highly interconnected; and that the increase in freezing tolerance that occurs with cold acclimation is only partially dependent on the CBf-CRT/DRE regulatory module.
(via Semantic Scholar)
Source: ORCID
Added: January 25, 2021
2015 journal article
Crystal structure and thermal expansion of a CsCe2Cl7 scintillator
Journal of Solid State Chemistry, 227, 142–149.
author keywords: X-ray diffraction; Crystal structure; Thermal expansion; Scintillator; Crystal growth
Sources: Crossref, NC State University Libraries
Added: September 4, 2020
2015 journal article
Cytosolic Fe-S Cluster Protein Maturation and Iron Regulation Are Independent of the Mitochondrial Erv1/Mia40 Import System
Journal of Biological Chemistry, 290(46), 27829–27840.
MeSH headings : Amino Acid Sequence; Cytosol / metabolism; Glutamate-Cysteine Ligase / metabolism; Glutathione / deficiency; Glutathione / metabolism; Iron / metabolism; Iron-Sulfur Proteins / metabolism; Mitochondria / metabolism; Mitochondrial Membrane Transport Proteins / genetics; Mitochondrial Membrane Transport Proteins / metabolism; Mitochondrial Precursor Protein Import Complex Proteins; Mitochondrial Proteins / genetics; Mitochondrial Proteins / metabolism; Molecular Sequence Data; Mutation; Oxidation-Reduction; Oxidoreductases / metabolism; Oxidoreductases Acting on Sulfur Group Donors / genetics; Oxidoreductases Acting on Sulfur Group Donors / metabolism; Protein Transport; Saccharomyces cerevisiae / genetics; Saccharomyces cerevisiae / metabolism; Saccharomyces cerevisiae / ultrastructure; Saccharomyces cerevisiae Proteins / genetics; Saccharomyces cerevisiae Proteins / metabolism
TL;DR:
These results confirm that GSH is critical for cytosolic Fe-S protein biogenesis and iron regulation, whereas ruling out significant roles for Erv1 or Mia40 in these pathways.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2015 journal article
Hyaluronidase Hyal1 Increases Tumor Cell Proliferation and Motility through Accelerated Vesicle Trafficking
Journal of Biological Chemistry, 290(21), 13144–13156.
MeSH headings : Adenocarcinoma / metabolism; Adenocarcinoma / pathology; Antigens, Neoplasm / metabolism; Apoptosis; Blotting, Western; Cell Movement; Cell Proliferation; Endocytosis / physiology; Endosomes / metabolism; Histone Acetyltransferases / metabolism; Humans; Hyaluronic Acid / metabolism; Hyaluronoglucosaminidase / metabolism; Male; Prostatic Neoplasms / metabolism; Prostatic Neoplasms / pathology; Protein Transport; Subcellular Fractions; Transferrin / metabolism; Transport Vesicles / metabolism; Tumor Cells, Cultured
TL;DR:
Overall, excess Hyal1 secretion accelerates endocytic vesicle trafficking in a substrate-dependent manner, promoting aggressive tumor cell behavior.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2015 review
Alphavirus Entry into Host Cells
[Review of ]. Molecular basis of viral infection, 129, 33–62.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Biology of reactive oxygen species, oxidative stress, and antioxidants in lactic acid bacteria
Probiotics and Prebiotics: Current Research and Future Trends, 205–218.
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2015 journal article
Structure-based approach to the identification of a novel group of selective glucosamine analogue inhibitors of Trypanosoma cruzi glucokinase
Molecular and Biochemical Parasitology, 204(2), 64–76.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
ELASTOGRAPHIC EVALUATION OF NATURALLY OCCURING TENDON AND LIGAMENT INJURIES OF THE EQUINE DISTAL LIMB
VETERINARY RADIOLOGY & ULTRASOUND, 56(6), 670–679.
author keywords: elastography; equine; musculoskeletal; ultrasound
MeSH headings : Acute Disease; Animals; Artifacts; Chronic Disease; Cohort Studies; Elasticity Imaging Techniques / veterinary; Follow-Up Studies; Forelimb / diagnostic imaging; Forelimb / injuries; Hindlimb / diagnostic imaging; Hindlimb / injuries; Horses / injuries; Image Processing, Computer-Assisted / methods; Lameness, Animal / diagnostic imaging; Ligaments / diagnostic imaging; Ligaments / injuries; Magnetic Resonance Imaging / veterinary; Prospective Studies; Soft Tissue Injuries / diagnostic imaging; Soft Tissue Injuries / veterinary; Tendon Injuries / diagnostic imaging; Tendon Injuries / veterinary
TL;DR:
Elastographic evaluation of equine tendons and ligaments may allow better characterization of lesion chronicity and severity, and sequential examinations may optimize lesion management, rehabilitation, and return to training.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 article
Persistent Virus-Induced Gene Silencing in Asymptomatic Accessions of Arabidopsis
PLANT FUNCTIONAL GENOMICS: METHODS AND PROTOCOLS, 2ND EDITION, Vol. 1284, pp. 305–322.
MeSH headings : Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis / virology; Begomovirus / physiology; Cloning, Molecular / methods; Gene Silencing; Gene Targeting / methods; Genetic Vectors / genetics; Host-Pathogen Interactions / genetics
TL;DR:
It is shown that genetic variation in the vast collection of Arabidopsis accessions can be leveraged to ameliorate viral symptomology that accompanies the VIGS procedure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Mitochondrial DNA Fragmentation to Monitor Processing Parameters in High Acid, Plant-Derived Foods
Journal of Food Science, 80(12), M2892–M2898.
author keywords: high-acid foods; mitochondrial DNA; quantitative PCR; thermal processing
MeSH headings : Acids; Bacteria / growth & development; Cucumis sativus / genetics; DNA Fragmentation; DNA, Mitochondrial; DNA, Plant / analysis; Fermentation; Food Analysis; Food Handling / methods; Food Microbiology; Food Preservation / methods; Fruit; Genes, Mitochondrial; Genes, Plant; Humans; Hydrogen-Ion Concentration; Solanum lycopersicum / genetics; Pasteurization; Plants, Edible / genetics; Temperature; Vegetables
TL;DR:
MtDNA fragmentation was shown to be a potential new tool to characterize low temperature (<100 °C) high acid processes (pH < 4.6), nonthermal processes such as vegetable fermentation and holding times of acidified, plant-derived products.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2015 journal article
Neutron Crystal Structure of RAS GTPase Puts in Question the Protonation State of the GTP gamma-Phosphate
JOURNAL OF BIOLOGICAL CHEMISTRY, 290(52), 31025–31036.
MeSH headings : Catalysis; Guanosine Triphosphate / analogs & derivatives; Guanosine Triphosphate / chemistry; Guanosine Triphosphate / genetics; Guanosine Triphosphate / metabolism; Humans; Hydrolysis; Neutrons; Protein Structure, Tertiary; Proto-Oncogene Proteins p21(ras) / chemistry; Proto-Oncogene Proteins p21(ras) / genetics; Proto-Oncogene Proteins p21(ras) / metabolism
TL;DR:
The neutron crystal structure of RAS bound to the GTP analogue GppNHp shows a protonated γ-phosphate at physiological pH, which counters the notion that the phosphate groups of GTP are fully deprotonated at the start of the hydrolysis reaction.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
8. Decent Work and Economic Growth
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2015 journal article
Rapid and Efficient Production of Coronary Artery Ligation and Myocardial Infarction in Mice Using Surgical Clips
PLOS ONE, 10(11).
MeSH headings : Animals; Coronary Vessels / surgery; Disease Models, Animal; Ligation; Mice; Myocardial Infarction / etiology; Myocardial Infarction / mortality; Myocardial Infarction / pathology; Myocardial Infarction / physiopathology; Surgical Instruments; Suture Techniques; Vascular Surgical Procedures
TL;DR:
This new method, taking only less than 3 minutes to complete, represents an efficient myocardial infarction model in rodents and improved post-MI survival rate.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Performing protein crosslinking using gas-phase cleavable chemical crosslinkers and liquid chromatography-tandem mass spectrometry
METHODS, 89, 64–73.
author keywords: Protein structure; Protein-protein interactions; Crosslinking; Gas-phase cleavable crosslinkers; CID-cleavable crosslinkers; Mass spectrometry
MeSH headings : Animals; Cattle; Chromatography, Liquid / methods; Cross-Linking Reagents / chemistry; Cross-Linking Reagents / metabolism; Protein Binding / physiology; Serum Albumin, Bovine / analysis; Serum Albumin, Bovine / metabolism; Tandem Mass Spectrometry / methods
TL;DR:
The CID-CXL-MS/MS approach can be used as a tool for biological research for studying protein structure when integrated with data obtained using other techniques, such as NMR, X-ray crystallography, and cryo-electron microscopy, or extended to the study of protein-protein interactions in physiological environments.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Isolation and Cryopreservation of Neonatal Rat Cardiomyocytes
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (98).
author keywords: Developmental Biology; Issue 98; Cryopreservation; Cardiomyocytes; Cell-based Assay; Cell Culture; Cardiac Research; In Vitro Assay
MeSH headings : Actinin / analysis; Actinin / metabolism; Animals; Animals, Newborn; Cell Culture Techniques; Cell Separation / methods; Cell Survival / physiology; Cryopreservation / methods; Cryoprotective Agents / chemistry; Dimethyl Sulfoxide / chemistry; Freezing; Myocytes, Cardiac / cytology; Myocytes, Cardiac / metabolism; Rats; Sarcomeres / chemistry; Sarcomeres / metabolism
TL;DR:
Cryopreservation methods allow one to easily cryopreserve and thaw neonatal rat cardiomyocytes, which gives researchers a greater amount of flexibility in planning experiments as well as reducing the use of animals.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 article
Cryopreservation of Neonatal Cardiomyocytes
CARDIOMYOCYTES: METHODS AND PROTOCOLS, Vol. 1299, pp. 153–160.
author keywords: Cardiomyocytes; Cryopreservation; Cardiac research
MeSH headings : Animals; Animals, Newborn; Cell Culture Techniques; Cells, Cultured; Cryopreservation / methods; Myocytes, Cardiac / cytology; Rats
TL;DR:
A method for cryopreserving neonatal rat cardiomyocytes (NRCMs), and subsequently thawing them for use in assays and to reduce the time requirements and the impact on research animals is described.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
COMPUTED TOMOGRAPHIC AND ULTRASONOGRAPHIC CHARACTERISTICS OF CAVERNOUS TRANSFORMATION OF THE OBSTRUCTED PORTAL VEIN IN SMALL ANIMALS
VETERINARY RADIOLOGY & ULTRASOUND, 56(5), 511–519.
author keywords: Cavernous transformation; CT-angiography; obstruction; portal collaterals; portal vein
MeSH headings : Angiography / veterinary; Animals; Cat Diseases / diagnostic imaging; Cats; Collateral Circulation; Cross-Sectional Studies; Dog Diseases / diagnostic imaging; Dogs; Female; Hypertension, Portal / diagnostic imaging; Hypertension, Portal / veterinary; Male; Multidetector Computed Tomography / veterinary; Portal Vein / abnormalities; Portal Vein / diagnostic imaging; Retrospective Studies
TL;DR:
Describing MDCT and ultrasonographic characteristics of presumed cavernous transformation of the portal vein in small animals with portal vein obstruction using ultrasound and multidetector-row computed tomography (MDCT) was provided.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Adult Lung Spheroid Cells Contain Progenitor Cells and Mediate Regeneration in Rodents With Bleomycin-Induced Pulmonary Fibrosis
STEM CELLS TRANSLATIONAL MEDICINE, 4(11), 1265–1274.
author keywords: Adult lung stem cells; Mesenchymal stem cells; Pulmonary fibrosis; Spheroid cell culture
MeSH headings : Adult; Animals; Antibiotics, Antineoplastic / adverse effects; Antibiotics, Antineoplastic / pharmacology; Bleomycin / adverse effects; Bleomycin / pharmacology; Female; Heterografts; Humans; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells / metabolism; Mesenchymal Stem Cells / pathology; Mice; Mice, SCID; Pulmonary Fibrosis / chemically induced; Pulmonary Fibrosis / metabolism; Pulmonary Fibrosis / pathology; Pulmonary Fibrosis / therapy; Regeneration; Spheroids, Cellular / metabolism; Spheroids, Cellular / transplantation
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
What is your diagnosis?
Journal of the American Veterinary Medical Association, 247(5), 471–473.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
NMR-based structural analysis of threonylcarbamoyl-AMP synthase and Its substrate interactions
Journal of Biological Chemistry, 290(33), 20032–20043.
Source: NC State University Libraries
Added: August 6, 2018
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