Works Published in 2010

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Displaying works 361 - 380 of 675 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2010 journal article

Echinacea and its alkylamides: Effects on the influenza A-induced secretion of cytokines, chemokines, and PGE(2) from RAW 264.7 macrophage-like cells

INTERNATIONAL IMMUNOPHARMACOLOGY, 10(10), 1268–1278.

By: N. Cech*, V. Kandhi*, J. Davis n, A. Hamilton n, D. Eads n & S. Laster n

author keywords: Echinacea; H1N1 influenza; Alkylamide; Isobutylamide; Plant extracts; Anti-inflammatory
TL;DR: In vitro experiments suggest that E. purpurea extracts have the potential for use in alleviating the symptoms and pathology associated with infections with influenza A; however, further study will be necessary to define procedures necessary to unmask the alkylamide activity in crude extracts. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Crystallization and preliminary X-ray diffraction analysis of red clover necrotic mosaic virus

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 66(Pt 11), 1458–1462.

By: S. Martin n, R. Guenther n, T. Sit n, P. Swartz n, F. Meilleur n, S. Lommel n, R. Rose n, F. Section

author keywords: red clover necrotic mosaic virus; dianthoviruses; viruses
MeSH headings : Crystallization; Crystallography, X-Ray; Microscopy, Electron, Transmission; Tombusviridae / chemistry; Tombusviridae / ultrastructure; Virion / chemistry; Virion / ultrastructure
TL;DR: Red clover necrotic mosaic virus is a species that belongs to the Tombusviridae family of plant viruses with a T = 3 icosahedral capsid and crystals diffracted to better than 4 Å resolution but were very radiation-sensitive, causing rapid decay of the high-resolution reflections. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Characterization of side population cells in human malignant mesothelioma cell lines

LUNG CANCER, 70(2), 146–151.

By: K. Kai n, S. D'Costa n, B. Yoon n, A. Brody n, R. Sills* & Y. Kim n

author keywords: Mesothelioma; Side population; Cancer stem cell; Hoechst 33342; Tumorigenicity; Flow cytometry
MeSH headings : Animals; Cell Line, Tumor; Cell Proliferation; Cell Separation; Cisplatin / pharmacology; Feasibility Studies; Flow Cytometry; Gene Expression Regulation, Developmental; Humans; Mesothelioma / diagnosis; Mesothelioma / drug therapy; Mesothelioma / pathology; Mice; Mice, SCID; Neoplasm Transplantation; Neoplastic Stem Cells / drug effects; Neoplastic Stem Cells / metabolism; Neoplastic Stem Cells / pathology; Side-Population Cells / drug effects; Side-Population Cells / metabolism; Side-Population Cells / pathology
TL;DR: The data indicated that SP assay may not be appropriate for enriching putative CSCs in HMM cell lines, and thus warrants the development of a novel tool for mesothelial CSC study. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Canopy and litter ant assemblages share similar climate-species density relationships

BIOLOGY LETTERS, 6(6), 769–772.

By: M. Weiser n, N. Sanders*, D. Agosti, A. Andersen*, A. Ellison*, B. Fisher*, H. Gibb*, N. Gotelli* ...

Contributors: M. Weiser n, N. Sanders*, D. Agosti, A. Andersen*, A. Ellison*, B. Fisher*, H. Gibb*, N. Gotelli* ...

author keywords: Formicidae; species richness; global diversity gradients
MeSH headings : Animals; Ants / physiology; Ecosystem; Linear Models; Models, Biological; Population Density; Species Specificity; Trees; Tropical Climate; Weather
TL;DR: It appears that canopy and litter ant assemblages share a common abundance–diversity relationship influenced by similar but not identical climatic drivers. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (OpenAlex)
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Antiplasmodial and cytotoxic activities of drimane sesquiterpenes from Canella winterana

Natural Product Communications, 5(12), 1869–1872.

By: M. Grace, C. Lategan, F. Mbeunkui, R. Graziose, P. Smith, I. Raskin, M. Lila

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Acute ANIT Toxicity in Male IL-10 Knockout and Wild-type Mice

TOXICOLOGIC PATHOLOGY, 38(5), 745–755.

By: B. Faiola*, R. Peterson*, C. Kimbrough*, H. Jordan* & J. Cullen n

author keywords: animal models; toxicologic pathology; hepatobiliary system; histopathology; knockout mouse; liver; mouse pathology
MeSH headings : Animals; Chemical and Drug Induced Liver Injury / genetics; Chemical and Drug Induced Liver Injury / metabolism; Chemical and Drug Induced Liver Injury / pathology; Gallbladder / drug effects; Gallbladder / pathology; Immunohistochemistry; Interleukin-10 / genetics; Isothiocyanates / toxicity; Male; Mice; Mice, Inbred C57BL; Mice, Knockout
TL;DR: It is suggested that IL-10 KO mice have less hepatocellular injury than WT mice following a toxic dose of ANIT and that biliary epithelial injury is accentuated in the KO mice. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 review

Accomplishments and new challenges in dairy genetic evaluations

[Review of ]. ITALIAN JOURNAL OF ANIMAL SCIENCE, 9(4), 360–368.

author keywords: Genetic improvement; Statistical methods; Livestock animals; Dairy sector; Review
TL;DR: The collection and analysis of several types of phenotypic data to evaluate genetic merit will continue to be the most important tool for genetic progress in the foreseeable future. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Ablation of TAK1 Upregulates Reactive Oxygen Species and Selectively Kills Tumor Cells

Cancer Research, 70(21), 8417–8425.

MeSH headings : 9,10-Dimethyl-1,2-benzanthracene / toxicity; Animals; Apoptosis; Blotting, Western; Carcinogens / toxicity; Cell Proliferation; Gene Deletion; Integrases / metabolism; Keratinocytes / cytology; Keratinocytes / drug effects; Keratinocytes / metabolism; MAP Kinase Kinase Kinases / antagonists & inhibitors; MAP Kinase Kinase Kinases / physiology; Mice; Mice, Knockout; Papilloma / chemically induced; Papilloma / metabolism; Papilloma / pathology; RNA, Messenger / genetics; RNA, Small Interfering / pharmacology; Reactive Oxygen Species / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Skin / metabolism; Skin / pathology; Skin Neoplasms / chemically induced; Skin Neoplasms / metabolism; Skin Neoplasms / pathology; Up-Regulation
TL;DR: TAK1 kinase could be a new and effective molecular target for ROS-based tumor killing and is examined whether ablation of TAK1 in preexisting skin tumors could cause an increase in ROS and result in tumor cell death. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2010 journal article

Vip3Aa Tolerance Response of Helicoverpa armigera Populations From a Cry1Ac Cotton Planting Region

JOURNAL OF ECONOMIC ENTOMOLOGY, 103(6), 2169–2173.

By: J. An*, Y. Gao, K. Wu, F. Gould*, J. Gao, Z. Shen, C. Lei

author keywords: Cry1Ac; Vip3Aa; Helicoverpa armigera; cross-tolerance
MeSH headings : Animals; Bacillus thuringiensis Toxins; Bacterial Proteins / pharmacology; Endotoxins / pharmacology; Gossypium / parasitology; Hemolysin Proteins / pharmacology; Insecticide Resistance; Insecticides / pharmacology; Larva; Moths
TL;DR: Levels of Vip3Aa tolerance in Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae) populations from the Cry1Ac cotton planting region in China are reported on based on bioassays of the F1 generation of isofemale lines, indicating that the threat of cross-resistance betweenCry1Ac and Vip 3A is low in field populations of H. armigersa. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
16. Peace, Justice and Strong Institutions (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 review

The Center of Accessibility: D beta Control of V(D)J Recombination

[Review of ]. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 58(6), 427–433.

author keywords: T cell receptor; Tcrb; Transcription; V(D)J recombination; Thymocytes; Double negative
MeSH headings : Acetylation; Animals; Chromatin Assembly and Disassembly; Epigenesis, Genetic; Gene Rearrangement, T-Lymphocyte; Genes, T-Cell Receptor beta; Histones / metabolism; Humans; Protein Processing, Post-Translational; Thymus Gland / enzymology; Thymus Gland / immunology; Transcription, Genetic; VDJ Recombinases / metabolism
TL;DR: Examining Tcrb assembly in developing thymocytes, the central roles of RSS elements and germline promoters as foci for epigenetic reorganization of recombinationally accessible gene segments are reviewed in light of recent findings and persistent questions. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Tetra-O-methyl nordihydroguaiaretic acid (Terameprocol) inhibits the NF-kappa B-dependent transcription of TNF-alpha and MCP-1/CCL2 genes by preventing RelA from binding its cognate sites on DNA

JOURNAL OF INFLAMMATION-LONDON, 7.

By: A. Oyegunwa n, M. Sikes n, J. Wilson n, F. Scholle n & S. Laster n

TL;DR: TMP acts indirectly as an inhibitor of NF-κB-dependent transcription by preventing RelA from binding the promoters of certain key cytokine and chemokine genes. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Sexual isolation of male moths explained by a single pheromone response QTL containing four receptor genes

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107(19), 8660–8665.

author keywords: mating; speciation; AFLP; odorant receptor; Heliothis
MeSH headings : Animal Structures / drug effects; Animal Structures / physiology; Animals; Chromosome Mapping; Chromosomes / genetics; Crosses, Genetic; Electrophysiological Phenomena / drug effects; Female; Genes, Insect / genetics; Inbreeding; Ketones / pharmacology; Male; Moths / drug effects; Moths / genetics; Neurons / drug effects; Neurons / physiology; Pheromones / pharmacology; Quantitative Trait Loci / genetics; Receptors, Odorant / genetics; Sexual Behavior, Animal / drug effects; Species Specificity
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

RSK-Mediated Phosphorylation in the C/EBP beta Leucine Zipper Regulates DNA Binding, Dimerization, and Growth Arrest Activity

MOLECULAR AND CELLULAR BIOLOGY, 30(11), 2621–2635.

By: S. Lee, J. Shuman, T. Guszczynski*, K. Sakchaisri, T. Sebastian, T. Copeland*, M. Miller*, M. Cohen* ...

MeSH headings : Amino Acid Sequence; Animals; CCAAT-Enhancer-Binding Protein-beta / chemistry; CCAAT-Enhancer-Binding Protein-beta / genetics; CCAAT-Enhancer-Binding Protein-beta / metabolism; Cell Cycle / physiology; Cell Line; DNA / genetics; DNA / metabolism; Growth Substances / metabolism; Humans; Leucine Zippers; MAP Kinase Signaling System / physiology; Mice; Mitogen-Activated Protein Kinases / antagonists & inhibitors; Mitogen-Activated Protein Kinases / genetics; Mitogen-Activated Protein Kinases / metabolism; Molecular Sequence Data; Phosphorylation; Protein Multimerization; Protein Processing, Post-Translational; Rats; Ribosomal Protein S6 Kinases / antagonists & inhibitors; Ribosomal Protein S6 Kinases / genetics; Ribosomal Protein S6 Kinases / metabolism; Sequence Alignment; Transcriptional Activation; ras Proteins / genetics; ras Proteins / metabolism
TL;DR: It is shown that C/EBPβ DNA binding is autorepressed and becomes activated by the Ras-Raf-MEK-ERK-p90RSK cascade and RSK-mediated phosphorylation of a bifunctional residue in the leucine zipper that regulates DNA binding and homodimerization and thereby promotes cell cycle arrest. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Proteomic Analysis Reveals Virus-Specific Hsp25 Modulation in Cardiac Myocytes

JOURNAL OF PROTEOME RESEARCH, 9(5), 2460–2471.

By: L. Li n, J. Sevinsky n, M. Rowland n, J. Bundy n, J. Stephenson n & B. Sherry n

author keywords: cardiac myocyte; myocarditis; reovirus; Hsp25; Hsp27; proteome; DIGE
MeSH headings : Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Cell Nucleus / metabolism; Cells, Cultured; Cytoplasm / metabolism; Electrophoresis, Gel, Two-Dimensional; Fibroblasts / metabolism; Heat-Shock Proteins / metabolism; Interferons / metabolism; Mice; Molecular Chaperones; Myocarditis / metabolism; Myocarditis / virology; Myocardium / cytology; Myocytes, Cardiac / metabolism; Myocytes, Cardiac / virology; Neoplasm Proteins / metabolism; Orthoreovirus, Mammalian; Phosphorylation; Principal Component Analysis; Proteomics / methods; Reoviridae Infections / metabolism; Reoviridae Infections / virology; Reproducibility of Results; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; p38 Mitogen-Activated Protein Kinases / metabolism
TL;DR: Results here provide the first evidence for a virus-induced decrease in Hsp25/27 and suggest that viruses may have evolved a mechanism to subvert this protective response, as they have for IFN. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Predicting Residential Air Exchange Rates from Questionnaires and Meteorology: Model Evaluation in Central North Carolina

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 44(24), 9349–9356.

By: M. Breen n, M. Breen n, R. Williams n & B. Schultz n

MeSH headings : Air Movements; Air Pollutants / analysis; Air Pollution, Indoor / analysis; Air Pollution, Indoor / statistics & numerical data; Atmosphere / chemistry; Environmental Monitoring / methods; Forecasting; Meteorological Concepts; Models, Chemical; North Carolina; Particle Size; Seasons; Surveys and Questionnaires
TL;DR: The capability of the LBL, LBLX, and SF models could help reduce the AER uncertainty in air pollution exposure models used to develop exposure metrics for health studies. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Photocaged T7 RNA Polymerase for the Light Activation of Transcription and Gene Function in Pro- and Eukaryotic Cells

CHEMBIOCHEM, 11(7), 972–977.

By: C. Chou n, D. Young n & A. Deiters n

author keywords: amino acids; caged proteins; light activation; polymerases; RNA
MeSH headings : Catalytic Domain; Cell Line; DNA-Directed RNA Polymerases / genetics; DNA-Directed RNA Polymerases / metabolism; Escherichia coli / enzymology; Humans; Luciferases / genetics; Luciferases / metabolism; Models, Molecular; Photochemical Processes; Transcriptional Activation; Tyrosine / chemistry; Ultraviolet Rays; Viral Proteins / genetics; Viral Proteins / metabolism
TL;DR: The ability to achieve spatiotemporal regulation of orthogonal RNA synthesis enables the precise dissection and manipulation of a wide range of cellular events, including gene function. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Photocaged Morpholino Oligomers for the Light-Regulation of Gene Function in Zebrafish and Xenopus Embryos

Journal of the American Chemical Society, 132(44), 15644–15650.

By: A. Deiters n, R. Garner n, H. Lusic n, J. Govan n, M. Dush n, N. Nascone-Yoder n, J. Yoder n

MeSH headings : Animals; Cells, Cultured; Embryo, Nonmammalian / metabolism; Gene Expression; Morpholines / chemistry; Oligonucleotides / genetics; Oligonucleotides / metabolism; Ultraviolet Rays; Xenopus laevis / genetics; Xenopus laevis / metabolism; Zebrafish / genetics; Zebrafish / metabolism
TL;DR: A novel and efficient synthetic route for incorporating photocaged monomeric building blocks directly into morpholino oligomers is reported and the utility of these caged morpholinos in the light-activated control of gene function in both cell culture and living embryos is demonstrated. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2010 journal article

On sparse estimation for semiparametric linear transformation models

JOURNAL OF MULTIVARIATE ANALYSIS, 101(7), 1594–1606.

author keywords: Censored survival data; Linear transformation models; LARS; Shrinkage; Variable selection
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Noncrossing quantile regression curve estimation

BIOMETRIKA, 97(4), 825–838.

By: H. Bondell n, B. Reich n & H. Wang n

author keywords: Crossing quantile curve; Heteroscedastic error; Quantile regression; Robustness; Smoothing spline; Tropical cyclone
TL;DR: A simple constrained version of quantile regression is proposed to avoid the crossing problem for both linear and nonparametric quantile curves. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Influence of calcium (0.6 or 1.2%) and phosphorus (0.3 or 0.6%) content and ratio on the formation of urolithogenic compounds in the urine of Boer-cross goats fed high-concentrate diets

SMALL RUMINANT RESEARCH, 93(2-3), 94–102.

By: S. Freeman n, M. Poore n, G. Young n & K. Anderson n

author keywords: Dietary calcium; Goats; Dietary phosphorus; Uroliths
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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