Works Published in 2004

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Displaying works 461 - 480 of 506 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2004 journal article

Genetic markers unique to Listeria monocytogenes serotype 4b differentiate epidemic clone II (hot dog outbreak strains) from other lineages

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 70(4), 2383–2390.

By: M. Evans n, B. Swaminathan*, L. Graves*, E. Altermann n, T. Klaenhammer n, R. Fink n, S. Kernodle n, S. Kathariou n

MeSH headings : Animals; Base Sequence; DNA Primers / genetics; DNA, Bacterial / genetics; Disease Outbreaks; Europe / epidemiology; Food Microbiology; Foodborne Diseases / epidemiology; Foodborne Diseases / microbiology; Genes, Bacterial; Genetic Markers; Humans; Listeria monocytogenes / classification; Listeria monocytogenes / genetics; Listeria monocytogenes / isolation & purification; Listeria monocytogenes / pathogenicity; Meat Products / microbiology; North America / epidemiology; Polymerase Chain Reaction; Serotyping
TL;DR: The findings suggest that ECII strains have undergone divergence in portions of a serotype-specific region that is conserved in other serotype 4b strains, although the mechanisms that drive this divergence remain to be identified. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Failure of FIV-infected cats to control Toxoplasma gondii correlates with reduced IL2, IL6, and IL12 and elevated IL10 expression by lymph node T cells

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 98(1-2), 101–111.

By: J. Levy*, Y. Liang n, J. Ritchey*, M. Davidson n, W. Tompkins n & M. Tompkins n

author keywords: FIV; cytokine; Toxoplasma gondii
MeSH headings : Animals; CD4-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / immunology; Cat Diseases / genetics; Cat Diseases / immunology; Cats; Gene Expression; Immunodeficiency Virus, Feline; Interleukin-10 / genetics; Interleukin-12 / genetics; Interleukin-2 / genetics; Interleukin-6 / genetics; Interleukins / genetics; Lentivirus Infections / complications; Lentivirus Infections / genetics; Lentivirus Infections / immunology; Lentivirus Infections / veterinary; RNA, Messenger / genetics; RNA, Messenger / metabolism; T-Lymphocytes / immunology; Toxoplasmosis, Animal / complications; Toxoplasmosis, Animal / genetics; Toxoplasmosis, Animal / immunology
TL;DR: Elevated IL10 may suppress a Th1 cytokine response to T. gondii challenge, and control and FIV-infected cats showed increased expression of IL2, IFNgamma, IL10, IL12, and IL6 mRNAs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Differential Treatment Benefit of Platelet Glycoprotein IIb/IIIa Inhibition With Percutaneous Coronary Intervention Versus Medical Therapy for Acute Coronary Syndromes

Circulation, 109(5), 641–646.

By: K. Pieper n, A. Tsiatis n, M. Davidian n, V. Hasselblad n, N. Kleiman n, E. Boersma n, W. Chang n, J. Griffin n ...

author keywords: trials; glycoproteins; coronary disease
MeSH headings : Acute Disease; Aged; Combined Modality Therapy; Coronary Disease / drug therapy; Coronary Disease / surgery; Female; Humans; Male; Middle Aged; Myocardial Revascularization; Patient Selection; Platelet Glycoprotein GPIIb-IIIa Complex / antagonists & inhibitors; Randomized Controlled Trials as Topic; Research Design; Syndrome; Treatment Outcome
TL;DR: Clinical-practice decisions and practice guidelines should be based on overall trial results and not analyses of post-randomization subgroups, based primarily on inappropriate subgroup analyses performed across the glycoprotein IIb/IIIa inhibitor trials. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2004 review

Decoding the genome: a modified view

[Review of ]. NUCLEIC ACIDS RESEARCH, 32(1), 223–238.

By: P. Agris n

MeSH headings : Animals; Anticodon / chemistry; Anticodon / genetics; Anticodon / metabolism; Base Sequence; Codon / chemistry; Codon / genetics; Codon / metabolism; Genetic Code; Genome; Humans; Protein Biosynthesis; RNA, Transfer / chemistry; RNA, Transfer / genetics; RNA, Transfer / metabolism; Thermodynamics
TL;DR: It is suggested that anticodon stem and loop domain nucleoside modifications allow a limited number of tRNAs to accurately and efficiently decode the 61 amino acid codons by selectively restricting some anticodon-codon interactions and expanding others. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Covalent attachment of a nickel nitrilotriacetic acid group to a germanium attenuated total reflectance element

LANGMUIR, 20(4), 1184–1188.

TL;DR: The surface of a germanium internal reflectance element (IRE) was modified to bind 6X-histidine (his)-tagged biomolecules and binding of his-tagged biotin to nickel nitrilotriacetic acid (Ni-NTA) was observed by ATR-FT-IR spectroscopy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2004 journal article

Cloning and transgenesis in mammals: Implications for xenotransplantation

AMERICAN JOURNAL OF TRANSPLANTATION, 4, 43–50.

By: J. Piedrahita n & B. Mir n

MeSH headings : Animals; Animals, Genetically Modified; Cloning, Organism; Embryo, Mammalian / cytology; Graft Rejection / etiology; Graft Rejection / immunology; Graft Rejection / prevention & control; Humans; Immune Tolerance; Immunosuppression Therapy; Nuclear Transfer Techniques; Stem Cells / cytology; Swine; Transplantation, Heterologous / immunology; Transplantation, Heterologous / methods; Transplantation, Heterologous / trends
TL;DR: Advances in transgenic manipulation and cloning in swine are reviewed and how the development of these two technologies is critical to the eventual utilization of the pig as a human organ donor. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Cat scratch disease and other zoonoticBartonellainfections

Journal of the American Veterinary Medical Association, 224(8), 1270–1279.

By: B. Chomel, H. Boulouis & E. Breitschwerdt*

MeSH headings : Aminoglycosides / therapeutic use; Animals; Anti-Bacterial Agents / therapeutic use; Bartonella / isolation & purification; Bartonella / pathogenicity; Bartonella Infections / epidemiology; Bartonella Infections / prevention & control; Bartonella Infections / transmission; Bartonella henselae / isolation & purification; Bartonella henselae / pathogenicity; Cat Diseases / epidemiology; Cat Diseases / prevention & control; Cat Diseases / transmission; Cat-Scratch Disease / epidemiology; Cat-Scratch Disease / prevention & control; Cat-Scratch Disease / transmission; Cats; Disease Reservoirs / veterinary; Dog Diseases / epidemiology; Dog Diseases / prevention & control; Dog Diseases / transmission; Dogs; Humans; Immunocompromised Host; Public Health; Zoonoses
TL;DR: Members of the genus Bartonella are maintained in many domesticated and wild animal hosts, and although these organisms have been implicated occasionally in illnesses, proving a causative role is difficult. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2004 journal article

Calcium and its role in the nuclear translocation and activation of cytosolic phospholipase A(2) in cells rendered sensitive to TNF-induced apoptosis by cycloheximide

JOURNAL OF IMMUNOLOGY, 172(4), 2416–2423.

By: D. Draper n, V. Harris*, C. Culver n & S. Laster n

MeSH headings : Active Transport, Cell Nucleus / drug effects; Active Transport, Cell Nucleus / immunology; Animals; Apoptosis / drug effects; Apoptosis / immunology; Arachidonic Acid / antagonists & inhibitors; Arachidonic Acid / metabolism; Calcium / metabolism; Calcium / physiology; Caspases / metabolism; Cell Line; Cell Nucleus / drug effects; Cell Nucleus / enzymology; Cell Nucleus / immunology; Cycloheximide / pharmacology; Cytosol / drug effects; Cytosol / enzymology; Cytosol / immunology; Enzyme Activation / drug effects; Enzyme Activation / immunology; Hydrolysis / drug effects; Intracellular Fluid / drug effects; Intracellular Fluid / immunology; Intracellular Fluid / metabolism; Mice; Mice, Inbred C3H; Phosphatidylserines / metabolism; Phospholipases A / metabolism; Phospholipases A2; Tritium; Tumor Necrosis Factor-alpha / pharmacology; Up-Regulation / drug effects; Up-Regulation / immunology; Verapamil / pharmacology
TL;DR: Data suggest that calcium is important for cPLA2 activation by diverse apoptotic stimuli, and verapamil prevented the release of [3H]arachidonic acid from C3HA cells induced to undergo apoptosis by the chemotherapeutic agents vinblastine, melphalan, and cis-platinum. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Assembly and kinetic folding pathways of a tetrameric beta-sheet complex: Molecular dynamics simulations on simplified off-lattice protein models

BIOPHYSICAL JOURNAL, 86(1), 31–49.

By: H. Jang n, C. Hall n & Y. Zhou*

MeSH headings : Binding Sites; Computer Simulation; Dimerization; Kinetics; Macromolecular Substances; Models, Chemical; Models, Molecular; Motion; Protein Binding; Protein Folding; Protein Structure, Secondary; Proteins / chemistry
TL;DR: Simulation of the assembly and folding kinetics of a tetrameric beta-sheet complex that contains four identical four-stranded antiparallel beta- sheet peptides indicates that intermediate eta values are most appropriate for modeling fibril formation and small etavalues are mostappropriate for modeling the formation of amorphous aggregates. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2004 journal article

Antigenic and genomic characterization of turkey enterovirus-like virus (North Carolina, 1988 isolate): Identification of the virus as turkey astrovirus 2

AVIAN DISEASES, 48(1), 206–211.

By: J. Guy n, A. Miles n, L. Smith n, F. Fuller n & S. Schultz-Cherry*

author keywords: turkey enterovirus; turkey astrovirus
MeSH headings : Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antigens, Viral; Capsid Proteins / genetics; Genome, Viral; Mamastrovirus / classification; Mamastrovirus / genetics; Mamastrovirus / immunology; Mamastrovirus / isolation & purification; Molecular Sequence Data; North Carolina; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Turkeys / virology; Viral Proteins / genetics
TL;DR: These studies definitively identify TELV (North Carolina, 1988 isolate), a small round virus isolated in 1988 from droppings of enteritis-affected turkeys in North Carolina, as turkey astrovirus 2 (TAstV2), a recently characterized SRV of turkeys. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2004 journal article

A tin-complexation strategy for use with diverse acylation methods in the preparation of 1,9-diacyldipyrromethanes

JOURNAL OF ORGANIC CHEMISTRY, 69(3), 765–777.

MeSH headings : Acylation; Crystallography, X-Ray; Indicators and Reagents / chemistry; Methane / analogs & derivatives; Methane / chemical synthesis; Methanol / analogs & derivatives; Molecular Structure; Organotin Compounds / chemistry; Porphyrins / chemical synthesis; Pyrroles / chemical synthesis; Pyrroles / chemistry
TL;DR: The tin-complexation strategy has broad scope, is compatible with diverse acylation methods, and greatly facilitates access to 1,9-diacyldipyrromethane-tin complexes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2004 journal article

A MARCKS-related peptide blocks mucus hypersecretion in a mouse model of asthma

NATURE MEDICINE, 10(2), 193–196.

By: M. Singer*, L. Martin n, B. Vargaftig*, J. Park n, A. Gruber, Y. Li n, K. Adler n

MeSH headings : Animals; Asthma / metabolism; Bronchi / cytology; Bronchi / metabolism; Bronchi / pathology; Bronchial Provocation Tests; Cytoplasmic Granules / metabolism; Cytoplasmic Granules / ultrastructure; Disease Models, Animal; Humans; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mucins / metabolism; Mucus / metabolism; Myristoylated Alanine-Rich C Kinase Substrate; Ovalbumin / administration & dosage; Ovalbumin / immunology; Peptide Fragments / administration & dosage; Peptide Fragments / chemistry; Peptide Fragments / pharmacology; Peptides / administration & dosage; Peptides / chemistry; Peptides / pharmacology; Proteins / chemistry; Proteins / genetics; Proteins / metabolism; Respiratory Mucosa / cytology; Respiratory Mucosa / metabolism
TL;DR: It is shown that the intratracheal instillation of this peptide blocks mucus hypersecretion in a mouse model of asthma, and a pivotal role for MARCKS protein, specifically its N-terminal region, in modulating this secretory process in mammalian airways is supported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Use of artificial androgen receptor coactivators to alter myoblast proliferation

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 91(3), 111–119.

author keywords: androgen receptor; muscle growth; coactivators
MeSH headings : Animals; Base Sequence; Cell Division / drug effects; DNA Primers; HeLa Cells; Humans; Muscle, Skeletal / cytology; Muscle, Skeletal / drug effects; Mutagenesis, Site-Directed; Rats; Receptors, Androgen / drug effects; Receptors, Androgen / metabolism
TL;DR: The ability of the mutated AR to act as an artificial coactivator to up-regulate androgen responsive genes is a useful tool for understanding the interaction of androgens and muscle growth. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Transcriptional analysis of dynamic heat-shock response by the hyperthermophilic bacterium Thermotoga maritima

EXTREMOPHILES, 8(3), 209–217.

By: M. Pysz n, D. Ward n, K. Shockley n, C. Montero n, S. Conners n, M. Johnson n, R. Kelly n

author keywords: cDNA microarray; groESL; heat shock; hrcA; hyperthermophile; Thermotoga
MeSH headings : Base Sequence; DNA, Bacterial / genetics; Endopeptidases / genetics; Gene Expression; Genome, Bacterial; Heat-Shock Response / genetics; Hot Temperature; Oligonucleotide Array Sequence Analysis; SOS Response, Genetics; Sigma Factor / genetics; Thermotoga maritima / genetics; Thermotoga maritima / metabolism; Transcription, Genetic
TL;DR: The results reported here indicate that, while T. maritima shares core elements of the bacterial heat-shock response with mesophiles, the thermal stress regulatory strategies of this organism differ significantly, and it remains to be elucidated whether these differences are related to thermophilicity or phylogenetic placement. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2004 journal article

The genome sequence of the probiotic intestinal bacterium Lactobacillus johnsonii NCC 533

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 101(8), 2512–2517.

By: R. Pridmore n, B. Berger n, F. Desiere n, D. Vilanova n, C. Barretto n, A. Pittet n, M. Zwahlen n, M. Rouvet n ...

MeSH headings : Biological Transport; Cell Adhesion; Energy Metabolism; Fimbriae, Bacterial / genetics; Genes, Bacterial / genetics; Genome, Bacterial; Humans; Intestinal Mucosa / microbiology; Lactobacillus / genetics; Lactobacillus / metabolism; Lactobacillus / pathogenicity; Molecular Sequence Data; Operon / genetics
TL;DR: Genome analysis predicted an abundance of large and unusual cell-surface proteins, including fimbrial subunits, which may be involved in adhesion to glycoproteins or other components of mucin, a characteristic expected to affect persistence in the gastrointestinal tract (GIT). (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2004 journal article

Structural control of the excited-state dynamics of bis(dipyrrinato)zinc complexes: Self-assembling chromophores for light-harvesting architectures

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 126(9), 2664–2665.

TL;DR: The results demonstrate that steric constraints on aryl-ring internal rotation dramatically alter the excited-state properties of 5,5'-substituted bis(dipyrrinato)metal complexes and establish the foundation for tuning the photophysical properties of these chromophores for use in diverse photochemical applications. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2004 journal article

Feasibility of using half-life multipliers to estimate extended withdrawal intervals following the extralabel use of drugs in food-producing animals

JOURNAL OF FOOD PROTECTION, 67(3), 555–560.

By: R. Gehring n, R. Baynes n, A. Craigmill* & J. Riviere n

MeSH headings : Algorithms; Animals; Animals, Domestic / metabolism; Drug Residues / analysis; Drug Residues / pharmacokinetics; Food Contamination / prevention & control; Half-Life; Legislation, Drug; Legislation, Veterinary; Meat / analysis; Models, Biological; Time Factors; United States; Veterinary Drugs / pharmacokinetics
TL;DR: For the group of drugs investigated, a half-life multiplier of 5 resulted in estimates of extended withdrawal intervals that were potentially inadequate to prevent violative tissue residues for drugs that had relatively long tissue half- Lives, high tolerances, or both. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Estimating mean response as a function of treatment duration in an observational study, where duration may be informatively censored

BIOMETRICS, 60(2), 315–323.

By: B. Johnson & A. Tsiatis*

author keywords: censored covariates; censored treatment; confounding; infusion length; inverse weighting; observational study; propensity score; survival analysis
MeSH headings : Biometry; Clinical Protocols; Coronary Artery Disease / drug therapy; Data Interpretation, Statistical; Eptifibatide; Humans; Peptides / therapeutic use; Platelet Aggregation Inhibitors / therapeutic use; Randomized Controlled Trials as Topic / statistics & numerical data; Time Factors; Treatment Outcome
TL;DR: An estimator for mean response as a function of treatment‐duration policy under conditions where treatment must be terminated prematurely due to an adverse event or until a treatment‐censoring event occurs, whichever comes first is proposed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Diverse redox-active molecules bearing identical thiol-terminated tripodal tethers for studies of molecular information storage

JOURNAL OF ORGANIC CHEMISTRY, 69(5), 1461–1469.

By: L. Wei n, K. Padmaja n, W. Youngblood n, A. Lysenko n, J. Lindsey n & D. Bocian n

UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2004 journal article

Estimating variability in models for recurrent epidemics: assessing the use of moment closure techniques

THEORETICAL POPULATION BIOLOGY, 65(1), 49–65.

By: A. Lloyd n

author keywords: demographic stochasticity; moment closure; epidemic models; nonlinear dynamics
MeSH headings : Demography; Disease Outbreaks; Humans; Models, Theoretical; Population Dynamics; Recurrence; Seasons; Stochastic Processes
TL;DR: This study assesses and compares the use of two moment closure approximations to estimate the variability seen about the average behavior of stochastic models for the recurrent epidemics seen in childhood diseases. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

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