Works Published in 2011
Displaying works 481 - 500 of 685 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2011 journal article
Degradation of sulfide by dehaloperoxidase-hemoglobin from Amphitrite ornata
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 16(4), 611–619.
author keywords: Sulfide; Dehaloperoxidase-hemoglobin; Resonance Raman; Detoxification; Oxygen
MeSH headings : Animals; Binding Sites; Biocatalysis; Hemoglobins / metabolism; Models, Molecular; Oxidation-Reduction; Peroxidase / metabolism; Polychaeta / chemistry; Polychaeta / enzymology; Sulfides / metabolism
TL;DR:
This proposed new function for DHP relies on the highly flexible distal His55 for deprotonation of the bound hydrogen sulfide, similar to H2O2 activation of the peroxidase function, and provides further support for the importance of the flexibility of the distal He55 in this novel globin.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2011 review
Current evidence of skin barrier dysfunction in human and canine atopic dermatitis
[Review of ]. VETERINARY DERMATOLOGY, 22(3), 239–248.
Contributors: R. Marsella *, T. Olivry n & D. Carlotti*
MeSH headings : Animals; Dermatitis, Atopic / immunology; Dermatitis, Atopic / metabolism; Dermatitis, Atopic / physiopathology; Dermatitis, Atopic / veterinary; Dog Diseases / immunology; Dog Diseases / metabolism; Dog Diseases / physiopathology; Dogs; Filaggrin Proteins; Humans
TL;DR:
Evidence is rapidly building to support a role for skin barrier dysfunction in canine AD, which shares many clinical and immunological similarities with its human counterpart.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2011 journal article
Connections between survey calibration estimators and semiparametric models for incomplete data discussion
International Statistical Review, 79(2), 221–223.
Source: NC State University Libraries
Added: August 6, 2018
2011 review
Capitalizing on the hydrophobic bias of electrospray ionization through chemical modification in mass spectrometry-based proteomics
[Review of ]. EXPERT REVIEW OF PROTEOMICS, 8(3), 317–323.
author keywords: ALiPHAT; electrospray ionization; hydrophobic tagging; mass spectrometry; quantification
MeSH headings : Humans; Hydrophobic and Hydrophilic Interactions; Proteomics / methods; Spectrometry, Mass, Electrospray Ionization / methods
TL;DR:
Improvements in targeted, mass spectrometry-based proteomic strategies are achieved by taking advantage of the mechanism of ESI through the use of hydrophobic chemical derivatization.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2011 journal article
Breed differences in pig temperament scores during a performance test and their phenotypic relationship with performance
LIVESTOCK SCIENCE, 136(2-3), 93–101.
Contributors: C. Yoder n, C. Maltecca n , J. Cassady n, W. Flowers n, S. Price & M. See n
author keywords: Breed; Performance; Pigs; Temperament
TL;DR:
Nucleus populations of Chester White, Duroc, Landrace, and Yorkshire boars and gilts were used to estimate breed differences in temperament and the relationship with performance, and vocal score was best described as two categories, vocal or non-vocal.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2011 journal article
Asymptotic properties of sufficient dimension reduction with a diverging number of predictors
Statistica Sinica, 21(2), 707–730.
Source: NC State University Libraries
Added: August 6, 2018
2011 journal article
Architecture of energy balance traits in emerging lines of the Collaborative Cross
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 300(6), E1124–E1134.
author keywords: genetics; wheel running; adiposity; body weight; quantitative trait loci
MeSH headings : Alleles; Analysis of Variance; Animals; Body Fat Distribution; Body Weight / genetics; Body Weight / physiology; Chromosome Mapping; Chromosomes / genetics; Crosses, Genetic; Eating / genetics; Eating / physiology; Energy Metabolism / genetics; Energy Metabolism / physiology; Genotype; Linkage Disequilibrium; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Motor Activity / physiology; Phenotype; Physical Conditioning, Animal / physiology; Quantitative Trait Loci; Running / physiology; Sample Size
TL;DR:
The results suggest that the CC will be a powerful, high-precision tool for examining the genetic architecture of complex traits such as those involved in regulation of energy balance.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Antibacterial efficacy of silver nanoparticles of different sizes, surface conditions and synthesis methods
NANOTOXICOLOGY, 5(2), 244–253.
author keywords: Silver; nanoparticles; nanotechnology; nanotoxicity; microbiology
MeSH headings : Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Escherichia coli / drug effects; Humans; Materials Testing; Metal Nanoparticles / chemistry; Metal Nanoparticles / ultrastructure; Methicillin-Resistant Staphylococcus aureus / drug effects; Microbial Sensitivity Tests; Particle Size; Silver / chemistry; Silver / pharmacology; Staphylococcus aureus / drug effects; Surface Properties
TL;DR:
Silver nanoparticles are used as a natural biocide to prevent undesired bacterial growth in clothing and cosmetics to assess the antibacterial efficacy of Ag-nps of different sizes, surface conditions, and synthesis methods against Escherichia coli, Ag-resistant E. coli, methicillin-resistant S. aureus, and Salmonella sp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Analysis of Manganese Tracer Kinetics and Target Tissue Dosimetry in Monkeys and Humans with Multi-Route Physiologically Based Pharmacokinetic Models
TOXICOLOGICAL SCIENCES, 120(2), 481–498.
author keywords: manganese; PBPK; inhalation exposure; risk assessment; neurotoxicity; pharmacokinetics
MeSH headings : Administration, Oral; Adult; Animals; Humans; Inhalation Exposure; Injections; Macaca mulatta; Manganese Compounds / pharmacokinetics; Metabolic Clearance Rate; Models, Biological; Organ Specificity; Physiology; Radioisotopes; Species Specificity; Time Factors; Tissue Distribution
TL;DR:
The use of this human Mn PBPK model can become a key component of future human health risk assessment, allowing the consideration of various exposure routes, natural tissue background levels, and homeostatic controls to explore exposure conditions that lead to increased target tissue levels resulting from Mn overexposure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
A Comparison of Multiple Esterases as Biomarkers of Organophosphate Exposure and Effect in Two Earthworm Species
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 86(4), 373–378.
author keywords: Biomarker; Esterase; Earthworm; Organophosphate
MeSH headings : Animals; Biomarkers / metabolism; Cholinesterase Inhibitors / toxicity; Dose-Response Relationship, Drug; Environmental Exposure / analysis; Esterases / metabolism; Insecticides / toxicity; Malathion / toxicity; Oligochaeta / drug effects; Oligochaeta / enzymology; Soil Pollutants / toxicity
TL;DR:
Two different earthworm species, Eisenia fetida and Lumbricus terrestris, were exposed to 5 μg/cm2 of malathion to evaluate their usefulness as sentinels of organophosphate exposure and to assess three different esterases, as biomarkers ofmalathion exposure and effect.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
"Candidatus Neoehrlichia mikurensis" Infection in a Dog from Germany
Journal of Clinical Microbiology, 49(5), 2059–2062.
MeSH headings : Anaplasmataceae / isolation & purification; Anaplasmataceae Infections / complications; Anaplasmataceae Infections / diagnosis; Anaplasmataceae Infections / microbiology; Anaplasmataceae Infections / veterinary; Animals; Cluster Analysis; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; DNA, Ribosomal / chemistry; DNA, Ribosomal / genetics; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Female; Germany; Molecular Sequence Data; Neutropenia / diagnosis; Phylogeny; RNA, Ribosomal, 16S / genetics; Sequence Analysis, DNA
TL;DR:
“Candidatus Neoehrlichia mikurensis” infection in a chronically neutropenic dog from Germany was confirmed by DNA sequencing by identifying a new intracellular pathogen associated with human infection and death.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2011 journal article
Variation in genome-wide mutation rates within and between human families
Nature Genetics, 43(7), 712–137.
Source: NC State University Libraries
Added: August 6, 2018
2011 journal article
VapC6, a ribonucleolytic toxin regulates thermophilicity in the crenarchaeote Sulfolobus solfataricus
RNA, 17(7), 1381–1392.
author keywords: antitoxin; RNA degradation; heat shock; archaea; transcription
MeSH headings : Adaptation, Physiological / genetics; Adaptation, Physiological / physiology; Cell Line; Gene Expression Profiling; Gene Expression Regulation, Archaeal; Hydrolysis / drug effects; Models, Biological; RNA / drug effects; RNA / metabolism; Sulfolobus solfataricus / genetics; Sulfolobus solfataricus / metabolism; Sulfolobus solfataricus / physiology; Temperature; Toxins, Biological / genetics; Toxins, Biological / metabolism; Toxins, Biological / pharmacology; Toxins, Biological / physiology
TL;DR:
The inactivation of the vapBC6 operon by targeted gene disruption produced two recessive phenotypes related to fitness, HS sensitivity and a heat-dependent reduction in the rate of growth that provide a biochemical mechanism and identify cellular targets underlying VapBC6-mediated control over microbial growth and survival at temperature extremes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2011 journal article
Ultrastructural changes in the equine colonic mucosa after ischaemia and reperfusion
Equine Veterinary Journal, 43(SUPPL.39), 8–15.
Contributors: A. Grosche*, A. Morton*, A. Graham*, L. Sanchez *, A. Blikslager n , M. Polyak*, D. Freeman *
author keywords: horse; colon; TEM; tight junctions; autophagy; phagocytosis; immune cells
MeSH headings : Animals; Colon / pathology; Colon / ultrastructure; Colonic Diseases / pathology; Colonic Diseases / veterinary; Horse Diseases / pathology; Horses; Intestinal Mucosa / pathology; Intestinal Mucosa / ultrastructure; Reperfusion Injury / pathology; Reperfusion Injury / veterinary
TL;DR:
The morphology and ultrastructural changes in the epithelium in equine large colonic mucosa after I/R, and the response of inflammatory cells to injury are described to provide information on early changes in barrier properties, repair and inflammation in Equine colon after ischaemia and reperfusion.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2011 journal article
The effects of a novel anti-inflammatory compound (AHI-805) on cyclooxygenase enzymes and the recovery of ischaemia injured equine jejunum ex vivo
Equine Veterinary Journal, 43(SUPPL.39), 106–111.
Contributors: J. Marshall*, A. Bhatnagar, S. Bowman*, N. Morris, D. Skorich, C. Redding n, A. Blikslager n
TL;DR:
Flunixin meglumine and AHI-805 inhibit recovery of barrier function in ischaemic-injured equine jejunum in vitro through inhibition of the COX enzymes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: NC State University Libraries, Crossref, ORCID
Added: August 6, 2018
2011 journal article
The effect of nonsteroidal anti-inflammatory drugs on the equine intestine
Equine Veterinary Journal, 43(SUPPL.39), 140–144.
Contributors: J. Marshall* & A. Blikslager n
author keywords: horse; NSAID; intestine; injury
MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / adverse effects; Gastrointestinal Diseases / chemically induced; Gastrointestinal Diseases / veterinary; Horse Diseases / chemically induced; Horses; Intestines / drug effects
TL;DR:
Experimental evidence suggests that those NSAIDs with cyclooxygenase independent anti-inflammatory effects or a COX-2 selective mode of action may offer significant advantages over traditional NSAIDs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2011 journal article
Suppression of COX-2, IL-1 beta and TNF-alpha expression and leukocyte infiltration in inflamed skin by bioactive compounds from Rosmarinus officinalis L.
FITOTERAPIA, 82(3), 414–421.
author keywords: Skin inflammation; Carnosic acid; Carnosol; Cyclooxygenase; Interleukin; Tumor necrosis factor
MeSH headings : Abietanes / pharmacology; Abietanes / therapeutic use; Animals; Cyclooxygenase 2 Inhibitors / pharmacology; Cyclooxygenase 2 Inhibitors / therapeutic use; Dose-Response Relationship, Drug; Fibronectins / genetics; Fibronectins / metabolism; Gene Expression; Inflammation / chemically induced; Inflammation / drug therapy; Inflammation / metabolism; Intercellular Adhesion Molecule-1 / genetics; Intercellular Adhesion Molecule-1 / metabolism; Interleukin-1beta / genetics; Interleukin-1beta / metabolism; Macrophages / drug effects; Macrophages / metabolism; Male; Mice; Mice, Inbred BALB C; Neutrophil Infiltration / drug effects; Nitric Oxide / biosynthesis; Phytotherapy; Plant Extracts / pharmacology; Plant Extracts / therapeutic use; Reverse Transcriptase Polymerase Chain Reaction; Rosmarinus / chemistry; Skin / drug effects; Skin / metabolism; Skin / pathology; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha / genetics; Tumor Necrosis Factor-alpha / metabolism
TL;DR:
It is shown for the first time in vivo that CA and CS differentially regulate the expression of inflammation-associated genes, thus demonstrating the pharmacological basis for the anti-inflammatory properties reported for CA andCS.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Successful management of gastrointestinal pythiosis in a dog using itraconazole, terbinafine, and mefenoxam
MEDICAL MYCOLOGY, 49(5), 539–542.
author keywords: pythiosis; dogs; terbinafine; itraconazole; mefenoxam
MeSH headings : Alanine / administration & dosage; Alanine / adverse effects; Alanine / analogs & derivatives; Animals; Antifungal Agents / administration & dosage; Antifungal Agents / adverse effects; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dogs; Duodenum / pathology; Female; Gastrointestinal Diseases / diagnosis; Gastrointestinal Diseases / drug therapy; Gastrointestinal Diseases / pathology; Gastrointestinal Diseases / veterinary; Histocytochemistry; Itraconazole / administration & dosage; Itraconazole / adverse effects; Naphthalenes / administration & dosage; Naphthalenes / adverse effects; Pythiosis / diagnosis; Pythiosis / drug therapy; Pythiosis / pathology; Pythiosis / veterinary; Pythium / isolation & purification; Terbinafine; Treatment Outcome
TL;DR:
A case of canine gastrointestinal pythiosis in which lesions were resolved through the administration of itraconazole, terbinafine, and the agricultural fungicide mefenoxam is described.
(via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2011 journal article
Spray-Dried Porcine Plasma Influences Intestinal Barrier Function, Inflammation, and Diarrhea in Weaned Pigs
JOURNAL OF NUTRITION, 141(7), 1312–1317.
MeSH headings : Animal Nutritional Physiological Phenomena; Animals; Cytokines / metabolism; Diarrhea / prevention & control; Diarrhea / veterinary; Dietary Supplements; Gastroenteritis / prevention & control; Gastroenteritis / veterinary; Intestinal Mucosa / metabolism; Intestines / physiology; Models, Animal; Plasma / physiology; Sus scrofa / blood; Sus scrofa / physiology; Swine; Swine Diseases / prevention & control; Weaning
TL;DR:
It is demonstrated that dietary inclusion of SDPP had beneficial effects on intestinal barrier function, inflammation, and diarrhea in weaned pigs.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Shift work in nurses: Contribution of phenotypes and genotypes to adaptation
PLoS One, 6(4).
Source: NC State University Libraries
Added: August 6, 2018
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