Works Published in 2011

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Displaying works 561 - 580 of 685 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2011 journal article

C/EBP alpha Expression Is Downregulated in Human Nonmelanoma Skin Cancers and Inactivation of C/EBP alpha Confers Susceptibility to UVB-Induced Skin Squamous Cell Carcinomas

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 131(6), 1339–1346.

MeSH headings : Animals; CCAAT-Enhancer-Binding Protein-alpha / analysis; CCAAT-Enhancer-Binding Protein-alpha / physiology; Carcinoma, Squamous Cell / chemistry; Carcinoma, Squamous Cell / etiology; Cell Cycle; Cells, Cultured; Genes, p53; Humans; Keratosis, Actinic / metabolism; Male; Mice; Mice, Hairless; Mice, Inbred C57BL; Mutation; Neoplasms, Radiation-Induced / etiology; Precancerous Conditions / chemistry; Skin / metabolism; Skin / radiation effects; Skin Neoplasms / chemistry; Skin Neoplasms / etiology; Ultraviolet Rays / adverse effects
TL;DR: It is observed that C/EBPα is induced in normal human epidermal keratinocytes and in the epidermis of human subjects exposed to UVB radiation, and loss of C/ EBPα confers susceptibility toUVB-induced skin SCCs involving defective cell cycle arrest in response to UVBs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Bartonella spp. DNA in Cardiac Tissues from Dogs in Colorado and Wyoming

Journal of Veterinary Internal Medicine, 25(3), 613–616.

By: A. Fenimore*, M. Varanat n, R. Maggi n, P. Schultheiss*, E. Breitschwerdt n & M. Lappin*

author keywords: Bartonella species; Blood cultures; Polymerase chain reaction assays
MeSH headings : Animals; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Colorado / epidemiology; DNA, Bacterial / isolation & purification; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dogs; Endocarditis, Bacterial / epidemiology; Endocarditis, Bacterial / microbiology; Endocarditis, Bacterial / veterinary; Retrospective Studies; Wyoming / epidemiology
TL;DR: The results emphasize the need for routine use of external parasite control products even in regions perceived to have low risk for flea and tick infestations and should be on the differential list for dogs in the Rocky Mountain states. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2011 journal article

Analysis of RNA-Mediated Materials Synthesis Using Magnetic Selection

JOURNAL OF PHYSICAL CHEMISTRY C, 115(19), 9335–9343.

By: S. Franzen n & D. Leonard*

UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Adipose-Derived Stem Cells in Functional Bone Tissue Engineering: Lessons from Bone Mechanobiology

TISSUE ENGINEERING PART B-REVIEWS, 17(3), 195–211.

By: J. Bodle n, A. Hanson n & E. Loboa n

MeSH headings : Adipose Tissue / cytology; Adipose Tissue / physiology; Adipose Tissue / transplantation; Animals; Humans; Mechanotransduction, Cellular / physiology; Osteogenesis / physiology; Stem Cell Transplantation / trends; Stem Cells / cytology; Stem Cells / physiology; Tissue Engineering / trends
TL;DR: The current knowledge base in bone mechanobiology is outlined to investigate how the knowledge from this area has been applied to the various stem cell-based approaches to engineering bone tissue constructs. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2011 journal article

A Common MUC5B Promoter Polymorphism and Pulmonary Fibrosis

NEW ENGLAND JOURNAL OF MEDICINE, 364(16), 1503–1512.

By: M. Seibold*, A. Wise*, M. Speer*, M. Steele*, K. Brown*, J. Loyd*, T. Fingerlin*, W. Zhang* ...

MeSH headings : Aged; Case-Control Studies; Chromosomes, Human, Pair 11; Female; Genetic Linkage; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Idiopathic Pulmonary Fibrosis / genetics; Linkage Disequilibrium; Lung / metabolism; Lung Diseases, Interstitial / genetics; Male; Middle Aged; Mucin-5B / genetics; Mucin-5B / metabolism; Mutation; Polymorphism, Single Nucleotide; Promoter Regions, Genetic
TL;DR: The findings suggest that dysregulated MUC5B expression in the lung may be involved in the pathogenesis of pulmonary fibrosis, and a common polymorphism in the promoter of M UC5B is associated with familial interstitial pneumonia and idiopathic pulmonary fibrot. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2011 article

comK Prophage Junction Fragments as Markers for Listeria monocytogenes Genotypes Unique to Individual Meat and Poultry Processing Plants and a Model for Rapid Niche-Specific Adaptation, Biofilm Formation, and Persistence (vol 77, pg 3279, 2011)

Verghese, B., Lok, M., Wen, J., Alessandria, V., Chen, Y., Kathariou, S., & Knabel, S. (2011, July). APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Vol. 77, pp. 5064–5064.

By: B. Verghese n, M. Lok n, J. Wen n, V. Alessandria n, Y. Chen n, S. Kathariou n, S. Knabel n

TL;DR: This research presents a novel and scalable approach to farming that combines horizontal and vertical integration that addresses the challenges of horizontal integration in the field of food safety and nutrition. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2011 journal article

YrdC exhibits properties expected of a subunit for a tRNA threonylcarbamoyl transferase

RNA, 17(9), 1678–1687.

By: K. Harris, V. Jones, Y. Bilbille, M. Swairjo & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

The gravity of life

Scientist, 25(6), 78–78.

By: R. Dunn

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

The Impact of Varying Environmental Conditions on the Spatial and Temporal Patterns of Orographic Precipitation over the Pacific Northwest near Portland, Oregon

JOURNAL OF HYDROMETEOROLOGY, 12(3), 329–351.

By: S. Yuter n, D. Stark n, J. Crouch n, M. Payne n & B. Colle*

UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Sufficient Dimension Reduction for Censored Regressions

BIOMETRICS, 67(2), 513–523.

By: W. Lu n & L. Li n

author keywords: Censored data; Central subspace; Inverse censoring probability weighted estimation; Sliced inverse regression; Sufficient dimension reduction
MeSH headings : Biometry / methods; Probability; Regression Analysis
TL;DR: A new class of inverse censoring probability weighted SDR estimators for censored regressions is proposed and regularization is introduced to achieve simultaneous variable selection and dimension reduction. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Resistance monitoring of Heliothis virescens to pyramided cotton varieties with a hydrateable, artificial cotton leaf bioassay

CROP PROTECTION, 30(9), 1196–1201.

By: A. Cabrera n, J. Van Kretschmar n, J. Bacheler n, H. Burrack n, C. Sorenson n & R. Roe n

author keywords: Bt; Tobacco budworm; Heliothis virescens; Cotton; Bollgard II; WideStrike; Resistance
TL;DR: Proof of concept was demonstrated for a practical, off-the-shelf bioassay to monitor for tobacco budworm resistance to pyramided Bt cotton using plant filtrates and showed it could be stored for at least 6 months at room temperature. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Refining tumor-associated aneuploidy through ‘genomic recoding’ of recurrent DNA copy number aberrations in 150 canine non-Hodgkin lymphomas

Leukemia & Lymphoma, 52(7), 1321–1335.

By: R. Thomas*, E. Seiser*, A. Motsinger-Reif*, L. Borst*, V. Valli, K. Kelley, S. Suter*, D. Argyle ...

author keywords: Comparative genomic hybridization (CGH); canine; lymphoma; chromosome; microarray
MeSH headings : Aneuploidy; Animals; Breeding; Comparative Genomic Hybridization; Cyclin-Dependent Kinase Inhibitor p16 / genetics; DNA Copy Number Variations / genetics; Dogs; Gene Expression Regulation, Neoplastic; Genomics; Immunophenotyping; Lymphoma, Non-Hodgkin / genetics; Lymphoma, Non-Hodgkin / pathology
TL;DR: It is hypothesized that the restricted genetic variation of purebred dogs, combined with the contrasting architecture of the human and canine karyotypes, will increase the penetrance of fundamental NHL-associated chromosomal aberrations in both species. (via Semantic Scholar)
Sources: Web Of Science, Crossref
Added: August 6, 2018

2011 journal article

Redox-Promoting Protein Motions in Rubredoxin

JOURNAL OF PHYSICAL CHEMISTRY B, 115(28), 8925–8936.

MeSH headings : Computer Simulation; Models, Molecular; Molecular Dynamics Simulation; Oxidation-Reduction; Rubredoxins / chemistry; Static Electricity
TL;DR: This study reports on the characterization of temperature-activated collective and individual atomic motions of oxidized rubredoxin, a small 53 residue protein from thermophilic Pyrococcus furiosus (RdPf). (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Physiologically Based Pharmacokinetic Modeling of Fetal and Neonatal Manganese Exposure in Humans: Describing Manganese Homeostasis during Development

TOXICOLOGICAL SCIENCES, 122(2), 297–316.

By: M. Yoon*, J. Schroeter*, A. Nong*, M. Taylor*, D. Dorman n, M. Andersen*, H. Clewell*

author keywords: manganese; potentially susceptible subpopulation; environmental exposure to Mn; formula; fetus; neonate
MeSH headings : Adult; Animals; Child, Preschool; Female; Fetus / drug effects; Fetus / metabolism; Homeostasis; Humans; Infant; Inhalation Exposure; Lactation; Male; Manganese / blood; Manganese / pharmacokinetics; Manganese / toxicity; Maternal Exposure; Milk, Human / chemistry; Models, Biological; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Tissue Distribution
TL;DR: A physiologically based pharmacokinetic model for Mn during human gestation and lactation was developed to predict Mn in fetal and neonatal brain using a parallelogram approach based upon extrapolation across life stages in rats and cross-species extrapolation to humans. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Performance Characteristics of a New Hybrid Quadrupole Time-of-Flight Tandem Mass Spectrometer (TripleTOF 5600)

ANALYTICAL CHEMISTRY, 83(13), 5442–5446.

By: G. Andrews n, B. Simons, J. Young, A. Hawkridge n & D. Muddiman n

MeSH headings : Fungal Proteins / metabolism; Proteome; Saccharomyces cerevisiae / metabolism; Tandem Mass Spectrometry / instrumentation; Trypsin / metabolism
TL;DR: The TripleTOF 5600 System, a hybrid quadrupole time-of-flight mass spectrometer, was evaluated to explore the key figures of merit in generating peptide and protein identifications that included spectral acquisition rates, data quality, proteome coverage, and biological depth. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Passive Immunization with a Polyclonal Antiserum to the Hemoglobin Receptor of Haemophilus ducreyi Confers Protection against a Homologous Challenge in the Experimental Swine Model of Chancroid

INFECTION AND IMMUNITY, 79(8), 3168–3177.

By: I. Leduc*, W. Fusco*, N. Choudhary*, P. Routh n, D. Cholon*, M. Hobbs*, G. Almond n, P. Orndorff n, C. Elkins*

MeSH headings : Animals; Antibodies, Bacterial / administration & dosage; Antibodies, Bacterial / immunology; Bacterial Proteins / immunology; Carrier Proteins / immunology; Chancroid / immunology; Chancroid / pathology; Chancroid / prevention & control; Disease Models, Animal; Ear / pathology; Haemophilus ducreyi / immunology; Haemophilus ducreyi / pathogenicity; Histocytochemistry; Immune Sera / administration & dosage; Immune Sera / immunology; Immunization, Passive / methods; Microbial Viability; Microscopy; Receptors, Cell Surface / immunology; Swine; Swine Diseases / immunology; Swine Diseases / prevention & control
TL;DR: Data suggest that the humoral immune response to the HgbA vaccine is protective against an H. ducreyi infection, possibly by preventing acquisition of the essential nutrient heme. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2011 journal article

One-step synthesis of silver nanoparticle-filled nylon 6 nanofibers and their antibacterial properties

JOURNAL OF MATERIALS CHEMISTRY, 21(28), 10330–10335.

By: Q. Shi n, N. Vitchuli n, J. Nowak n, J. Noar n, J. Caldwell n, F. Breidt n, M. Bourham n, M. McCord n, X. Zhang n

TL;DR: These silver nanoparticle-filled nylon 6 nanofibers exhibit a steady and long-lasting silver ion release behavior, and robust antibacterial activity against both Gram-positive B. cereus and Gram-negative E. coli microorganisms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Molecular cytogenetic characterization of canine histiocytic sarcoma: A spontaneous model for human histiocytic cancer identifies deletion of tumor suppressor genes and highlights influence of genetic background on tumor behavior

BMC Cancer, 11.

By: B. Hedan, R. Thomas, A. Motsinger-Reif, J. Abadie, C. Andre, J. Cullen, M. Breen

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Molecular and Serological Diagnosis of Bartonella Infection in 61 Dogs from the United States

Journal of Veterinary Internal Medicine, 25(4), 805–810.

By: C. Pérez n, R. Maggi n, P. Diniz n & E. Breitschwerdt n

author keywords: Bacteria; BAPGM; Bartonella; Blood culture
MeSH headings : Animals; Antibodies, Bacterial / blood; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / blood; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Culture Media; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Fluorescent Antibody Technique, Indirect / veterinary; Logistic Models; Multivariate Analysis; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Retrospective Studies
TL;DR: Dogs were most often infected with B. henselae or B. berkhoffii based on PCR and enrichment culture, coinfection was documented, and various Bartonella species were identified. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2011 journal article

Light-Activated Gene Editing with a Photocaged Zinc-Finger Nuclease

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 50(30), 6839–6842.

By: C. Chou n & A. Deiters n

author keywords: caged compounds; gene technology; light-activation; mutagenesis; zinc-finger nucleases
MeSH headings : Endonucleases / genetics; Endonucleases / metabolism; Escherichia coli / genetics; HEK293 Cells; Humans; Models, Molecular; Mutagenesis; Photochemical Processes; Protein Engineering; Tyrosine / genetics; Ultraviolet Rays; Zinc Fingers
TL;DR: A family of artificial restriction enzymes, namely zinc-finger nucleases (ZFN), has been developed to sequence-selectively achieve dsDNA scission and have since emerged as important and widely recognized tools for the genetic modification of cells, model organisms, and possibly humans to investigate gene function and to treat genetic disorders. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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