Works Published in 2022

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Displaying works 621 - 640 of 652 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2022 journal article

The pharmacokinetics of transdermal flunixin in lactating dairy goats

JOURNAL OF DAIRY SCIENCE, 105(1), 549–559.

By: E. Meira n, E. Wiloch n, E. Nixon n, J. Yeatts n, F. Sheela n, G. Smith n, R. Baynes n

author keywords: transdermal flunixin; goat; pharmacokinetics; drug residue; milk
MeSH headings : Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Clonixin / analogs & derivatives; Female; Goats; Lactation; Milk / chemistry
TL;DR: Evaluated the pharmacokinetics of transdermal flunixin in dairy goats to determine a milk withdrawal interval (WDI) to avoid violative residue contamination in the food supply and propose safe residue levels in goat milk provides a milk WDI of 60 h using the US Food and Drug Administration tolerance limit method. (via Semantic Scholar)
Source: Web Of Science
Added: January 3, 2022

2022 journal article

In Silico Identification and Experimental Validation of Peptide-Based Inhibitors Targeting Clostridium difficile Toxin A

ACS Chemical Biology, 17(1), 118–128.

MeSH headings : Bacterial Toxins / antagonists & inhibitors; Bacterial Toxins / chemistry; Computer Simulation; Drug Design; Enterotoxins / antagonists & inhibitors; Enterotoxins / chemistry; Models, Molecular; Peptides / chemistry; Peptides / pharmacology; Protein Binding; Protein Conformation; Protein Domains; Reproducibility of Results
TL;DR: This work used a computational strategy that integrates a peptide binding design algorithm and explicit-solvent atomistic molecular dynamics simulation to determine promising toxin A-targeting peptides that can recognize and bind to the catalytic site of the TcdA glucosyltransferase domain (GTD). (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: December 30, 2021

2022 journal article

Temperature Cycling Enables Efficient 13C SABRE-SHEATH Hyperpolarization and Imaging of [1-13C]-Pyruvate

Journal of the American Chemical Society, 12(1), 282–287.

MeSH headings : Pyruvic Acid
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure (OpenAlex)
Source: ORCID
Added: December 24, 2021

2022 journal article

The evolution of innate immune receptors: investigating the diversity, distribution, and phylogeny of immune recognition across eukaryotes

Immunogenetics, 74(1), 1–4.

MeSH headings : Eukaryota; Evolution, Molecular; Immunity, Innate / genetics; Phylogeny; Receptors, Immunologic
TL;DR: The diversity of IIRs from plants, vertebrates, invertebrate deuterostomes, a range of protostome invertebrates and basal metazoans is explored, and it is suggested that, to fully understand eukaryotic immune systems, further investigations of these proteins are warranted. (via Semantic Scholar)
Source: ORCID
Added: December 15, 2021

2022 review

Cyclodextrin-based nanostructures

[Review of ]. PROGRESS IN MATERIALS SCIENCE, 124.

author keywords: Cyclodextrins; Nanofibers; Nanoparticles; Nanorods; Nanomicelles; Inclusion complexation
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: December 13, 2021

2022 journal article

Order‐Unity 13C Nuclear Polarization of [1‐13C]Pyruvate in Seconds and the Interplay of Water and SABRE Enhancement

ChemPhysChem, 23(2).

Contributors: I. Adelabu*, P. TomHon n, M. Kabir*, S. Nantogma*, M. Abdulmojeed n, I. Mandzhieva n, J. Ettedgui*, R. Swenson* ...

author keywords: hyperpolarization; NMR spectroscopy; parahydrogen; C-13; pyruvate
MeSH headings : Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Pyruvic Acid; Water / chemistry
TL;DR: Signal Amplification By Reversible Exchange in SHield Enabled Alignment Transfer (SABRE-SHEATH) is investigated to achieve rapid hyperpolarization of 13C1 spins of [1-13C]pyruvate, using parahydrogen as the source of nuclear spin order. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: ORCID
Added: December 10, 2021

2022 journal article

Determination of the efficacy rate and time‐to‐efficacy of subcutaneous immunotherapy in dogs with atopic dermatitis

Veterinary Dermatology, 33(2), 155.

By: H. Tham* & T. Olivry n

MeSH headings : Allergens; Animals; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / veterinary; Desensitization, Immunologic / methods; Desensitization, Immunologic / veterinary; Dog Diseases / drug therapy; Dogs; Immunotherapy / methods; Immunotherapy / veterinary; Injections, Subcutaneous / veterinary; Pruritus / veterinary
TL;DR: Novel SCIT regimens appear to have a faster - and possibly higher - efficacy than the currently available aqueous or alum-precipitated formulations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: December 10, 2021

2022 journal article

Monitoring decellularization via absorbance spectroscopy during the derivation of extracellular matrix scaffolds

BIOMEDICAL MATERIALS, 17(1).

author keywords: extracellular matrix; manufacturing; decellularization; monitoring; vocal fold
MeSH headings : Biocompatible Materials; Extracellular Matrix / chemistry; Hydrogels; Regenerative Medicine; Spectrum Analysis; Tissue Engineering / methods; Tissue Scaffolds
TL;DR: Monitoring the bioreactor’s effluent absorbance at 260 nm as a function of time will provide a representative DNA release profile from the tissue and thus allow for process optimization, showing that absorbance profiles are a good representation of DNA removal during the decellularization process thus providing an important tool to optimize future protocols. (via Semantic Scholar)
Source: Web Of Science
Added: December 6, 2021

2022 journal article

In situ grown bacterial cellulose/MoS2 composites for multi-contaminant wastewater treatment and bacteria inactivation

CARBOHYDRATE POLYMERS, 277.

By: H. Shen*, S. Liao*, C. Jiang n, J. Zhang*, Q. Wei*, R. Ghiladi n, Q. Wang*

author keywords: Antibacterial; Bacterial cellulose; Molybdenum disulfide(MoS2); Peroxidase-like catalytic activity; Photocatalytic; Photothermal
MeSH headings : Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Cellulose / chemistry; Cellulose / pharmacology; Disulfides / chemistry; Disulfides / pharmacology; Escherichia coli / drug effects; Microbial Sensitivity Tests; Molybdenum / chemistry; Molybdenum / pharmacology; Staphylococcus aureus / drug effects; Wastewater / microbiology; Water Purification
Sources: Web Of Science, NC State University Libraries
Added: November 29, 2021

2022 journal article

Direct injection of Amblyomma americanum ticks with Cytauxzoon felis

TICKS AND TICK-BORNE DISEASES, 13(1).

By: T. Yang n, M. Reichard*, H. Marr n, L. Cohn*, L. Nafe*, N. Whitehurst n, A. Birkenheuer n

author keywords: Cytauxzoon felis; Direct injection; Tick; In situ hybridization
MeSH headings : Amblyomma; Animals; Cat Diseases / epidemiology; Cats; Felis; Ixodidae / parasitology; Protozoan Infections, Animal / parasitology; Ticks
TL;DR: The results suggest that injected C. felis remained alive in ticks but was unable to progress to infective sporozoites after injection, and the potential of using ticks as an alternative model to study C.Felis is demonstrated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: November 23, 2021

2022 journal article

EPR Oximetry with Nitroxides: Effects of Molecular Structure, pH, and Electrolyte Concentration

Applied Magnetic Resonance.

By: M. Voinov n, T. Smirnova n & A. Smirnov n

UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: ORCID
Added: November 20, 2021

2022 journal article

Beneficial effects of eicosapentaenoic acid on the metabolic profile of obese female mice entails upregulation of HEPEs and increased abundance of enteric Akkermansia muciniphila

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1867(1).

By: A. Pal*, S. Sun*, M. Armstrong*, J. Manke*, N. Reisdorph*, V. Adams n, A. Kennedy n, Y. Zu* ...

author keywords: N-3 polyunsaturated fatty acids; bacteria; Microbial; Lipidomics
MeSH headings : Akkermansia / genetics; Akkermansia / growth & development; Animals; Cardiometabolic Risk Factors; Cell Differentiation / drug effects; Diet, High-Fat / adverse effects; Eicosapentaenoic Acid / metabolism; Eicosapentaenoic Acid / pharmacology; Female; Gastrointestinal Microbiome / drug effects; Gastrointestinal Microbiome / genetics; Glucose / metabolism; Humans; Hydroxyeicosatetraenoic Acids / biosynthesis; Hydroxyeicosatetraenoic Acids / blood; Male; Mass Spectrometry; Mice; Mice, Obese / genetics; Mice, Obese / microbiology; Phosphatidylinositol 3-Kinases / genetics; Proto-Oncogene Proteins c-akt / genetics; RNA, Ribosomal, 16S / genetics; Sex Characteristics; Th17 Cells / metabolism; Triglycerides / blood
TL;DR: Results show that EPA ethyl esters prevent some of the deleterious effects of a high fat diet in female mice, which may be mediated mechanistically through 8-HEPE and the upregulation of intestinal Akkermansia muciniphila. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 8, 2021

2022 journal article

Identification of major and minor chicken allergens in dogs

Veterinary Dermatology, 33(1), 46.

MeSH headings : Allergens; Animals; Chickens; Cross Reactions; Dog Diseases; Dogs; Enzyme-Linked Immunosorbent Assay / veterinary; Hypersensitivity / veterinary; Immunoglobulin E
TL;DR: Seven major chicken allergens for dogs are identified and exhibit the theoretical potential to be cross-reactive between poultry and mammalian meats; six of these allergens already are known to beCross- reactive between chicken and fish species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: November 4, 2021

2022 journal article

Evaluation of a nutritional supplement for the alleviation of pain associated with feline degenerative joint disease: a prospective, randomized, stratified, double-blind, placebo-controlled clinical trial

Journal of Feline Medicine and Surgery.

By: R. Cunningham n, M. Gruen n, A. Thomson n & B. Lascelles n

author keywords: Glucosamine hydrochloride; chondroitin sulfate; nutritional supplement; mobility; accelerometer; activity
MeSH headings : Animals; Cat Diseases / drug therapy; Cats; Chondroitin Sulfates / therapeutic use; Double-Blind Method; Glucosamine / therapeutic use; Joint Diseases / veterinary; Musculoskeletal Pain / drug therapy; Musculoskeletal Pain / veterinary; Prospective Studies; Quality of Life; Treatment Outcome
TL;DR: This study showed a strong placebo effect and the glucosamine/chondroitin sulfate supplement did not show pain-relieving effects when compared with placebo, and no differences in activity were seen between the groups. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: ORCID
Added: November 2, 2021

2022 journal article

Interpretable machine learning applied to on‐farm biosecurity and porcine reproductive and respiratory syndrome virus

Transboundary and Emerging Diseases.

By: A. Sykes n, G. Silva*, D. Holtkamp*, B. Mauch*, O. Osemeke*, D. Linhares*, G. Machado n

author keywords: disease of swine; interpretable machine learning; on-farm biosecurity; PRRSV
MeSH headings : Animal Husbandry / methods; Animals; Biosecurity; Disease Susceptibility / veterinary; Farms; Humans; Machine Learning; Porcine Reproductive and Respiratory Syndrome / epidemiology; Porcine Reproductive and Respiratory Syndrome / prevention & control; Porcine respiratory and reproductive syndrome virus; Swine
TL;DR: A novel interpretable machine learning toolkit was developed to benchmark farms and production systems by predicted risk, and quantify the impact of biosecurity practices on disease risk at individual farms. (via Semantic Scholar)
Source: ORCID
Added: November 1, 2021

2022 journal article

Restoring Carboxylates on Highly Modified Alginates Improves Gelation, Tissue Retention and Systemic Capture

ACTA BIOMATERIALIA, 138, 208–217.

By: C. Moody n, A. Brown n, N. Massaro n, A. Patel n, P. Agarwalla n, A. Simpson n, A. Brown n, H. Zheng n, J. Pierce n, Y. Brudno n

author keywords: Alginate; Click chemistry; Bioconjugation; Ionic cross-linking; Drug capture
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries
Added: October 31, 2021

2022 article

Evaluating the Effects of the Circadian Clock and Time of Day on Plant Gravitropic Responses

PLANT GRAVITROPISM, Vol. 2368, pp. 301–319.

By: J. Tolsma n, J. Torres*, J. Richards*, I. Perera n & C. Doherty n

author keywords: Circadian; Gravistimulation; Time of day; Diel; Simulated microgravity
MeSH headings : Arabidopsis / metabolism; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Circadian Clocks; Circadian Rhythm; Gene Expression Regulation, Plant; Gravitropism; Photoperiod
TL;DR: It is critical to consider the time of day when performing gravitropism experiments, even if the circadian clock is not a focus of study. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science; OpenAlex)
13. Climate Action (Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: October 14, 2021

2022 journal article

Modelling the role of mortality‐based response triggers on the effectiveness of African swine fever control strategies

Transboundary and Emerging Diseases.

By: G. Machado n, T. Farthing n, M. Andraud*, F. Lopes* & C. Lanzas n

author keywords: network modelling; secure business continuity; surveillance; swine disease dynamics
MeSH headings : African Swine Fever / epidemiology; African Swine Fever / prevention & control; African Swine Fever Virus / physiology; Animals; Disease Outbreaks / veterinary; Epidemics / prevention & control; Epidemics / veterinary; Farms; Swine; Swine Diseases / epidemiology
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: ORCID
Added: September 30, 2021

2022 journal article

Transient and reversible reduction of stratum corneum filaggrin degradation products after allergen challenge in experimentally mite‐sensitised atopic dogs

Veterinary Dermatology, 33(1), 62.

By: T. Olivry n, J. Paps n & N. Amalric

MeSH headings : Allergens; Animals; Dermatitis, Atopic / veterinary; Dog Diseases; Dogs; Epidermis; Filaggrin Proteins; Mites; Skin
TL;DR: In this experimental model, a single epicutaneous allergen challenge led to a transient and reversible decrease in skin surface NMF and its components, and concentrations were negatively correlated with skin lesion scores. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: September 15, 2021

2022 journal article

Foaming and sensory characteristics of protein-polyphenol particles in a food matrix

Food Hydrocolloids.

By: J. Diaz n, E. Foegeding n, L. Stapleton, C. Kay n, M. Iorizzo n, M. Ferruzzi n, M. Lila n

author keywords: Particles; Polyphenols; Proteins; Foaming; Sensory; Structure
UN Sustainable Development Goal Categories
Source: ORCID
Added: August 26, 2021

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