Works Published in 2008

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Displaying works 121 - 140 of 637 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2008 journal article

W1738 Gastroprotective Properties of Cobiprostone Against Acid and NSAID-Induced Mucosal Injury in Porcine Gastric Mucosa

Gastroenterology, 134(4), A-705.

By: M. Nighot, R. Ueno, B. Roerig, K. Ryan, A. Blikslager* & A. Moeser

Sources: Crossref, NC State University Libraries
Added: September 8, 2020

2008 journal article

T1298 Comparison of the Effects of a COX-2 Selective Inhibitor (Firocoxib) and a Traditional NSAID (Flunixin Meglumine) On Recovery of Ischemic-Injured Equine Jejunum

Gastroenterology, 134(4), A-525-A-526.

By: V. Cook, C. Meyer, N. Campbell, J. Davis & A. Blikslager*

Sources: Crossref, NC State University Libraries
Added: September 8, 2020

2008 journal article

Molecular Characterization of Bartonella vinsonii subsp. berkhoffii Genotype III

Journal of Clinical Microbiology, 46(5), 1858–1860.

By: M. Cadenas n, J. Bradley n, R. Maggi n, M. Takara n, B. Hegarty n & E. Breitschwerdt n

MeSH headings : Animals; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Blood / microbiology; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Dog Diseases / microbiology; Dogs; Endocarditis, Bacterial / microbiology; Female; Genes, Bacterial; Genotype; Molecular Sequence Data
TL;DR: The molecular characterization of a Bartonella vinsonii subsp. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 1, 2020

2008 journal article

DNA-Templated Polymerization of Side-Chain-Functionalized Peptide Nucleic Acid Aldehydes

Journal of the American Chemical Society, 130(14), 4646–4659.

MeSH headings : Aldehydes / chemical synthesis; Aldehydes / chemistry; DNA / chemical synthesis; DNA / chemistry; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Nucleic Acid Conformation; Peptide Nucleic Acids / chemistry; Polymers / chemical synthesis; Spectrometry, Mass, Electrospray Ionization
TL;DR: The findings represent a significant step toward the evolution of sequence-defined synthetic polymers and also demonstrate that enzyme-free nucleic acid-templated polymerization can occur efficiently using substrates with a wide range of side-chain structures, functionalization positions within each building block, and functionalization densities. (via Semantic Scholar)
Sources: Crossref, ORCID, NC State University Libraries
Added: August 28, 2020

2008 journal article

Exercise enhances vaccine-induced antigen-specific T cell responses

Vaccine, 26(42), 5407–5415.

By: C. Rogers*, D. Zaharoff*, K. Hance*, S. Perkins*, S. Hursting*, J. Schlom*, J. Greiner*

author keywords: adaptive immunity; cytokines; cell proliferation
MeSH headings : Animals; Body Composition; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / metabolism; Cell Proliferation; Cytokines / biosynthesis; Cytokines / immunology; Female; Lymphocyte Activation / immunology; Mice; Mice, Inbred C57BL; Motor Activity; Ovalbumin / immunology; Substrate Specificity; Vaccination
TL;DR: Coupling moderate exercise with vaccination may enhance vaccine efficacy for the prevention and/or therapy of numerous diseases. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: August 28, 2020

2008 journal article

T1820 Enteric Glial Cells Promote Wound Healing of Intestinal Epithelial Barrier in Part Via a FAK-Dependent Pathway

Gastroenterology, 134(4), A-570.

By: L. Van Landeghem*, P. Derkinderen, P. Aubert, H. Enslen, I. Guisle-Marsollier, J. Léger, J. Galmiche, T. Savidge, M. Neunlist

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Crossref
Added: August 28, 2020

2008 journal article

163. Timing of Glucagon-Like Peptide-2 (GLP-2) Required for Augmented Expansion of Intestinal Stem Cells Following Ileo-Cecal Resection (ICR) in Mice

Journal of Surgical Research, 144(2), 249–250.

By: A. Garrison*, C. Dekaney*, D. von Allmen*, S. Henning* & M. Helmrath*

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Crossref
Added: August 28, 2020

2008 journal article

29. Bacterial Dependent up Regulation of Ileal Bile Acid Binding Protein and Bile Acid Transporters Is FXR-Mediated Following Ileo-Cecal Resection (ICR)

Journal of Surgical Research, 144(2), 188–189.

By: C. Dekaney*, D. von Allmen*, A. Garrison*, R. Rigby*, P. Lund*, S. Henning*, M. Helmrath*

UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: August 28, 2020

2008 journal article

Regulation of ornithine aminotransferase gene expression and activity by all-transretinoic acid in Caco-2 intestinal epithelial cells

The Journal of Nutritional Biochemistry, 19(10), 674–681.

By: C. Dekaney*, G. Wu*, Y. Yin & L. Jaeger*

author keywords: retinoic acid; ornithine aminotransferase; polyamines; intestinal cells
MeSH headings : Biogenic Polyamines / metabolism; Blotting, Northern; Caco-2 Cells; Epithelial Cells / drug effects; Epithelial Cells / enzymology; Epithelial Cells / metabolism; Gene Expression Regulation, Enzymologic / drug effects; Humans; Intestinal Mucosa / metabolism; Intestines / cytology; Intestines / drug effects; Intestines / enzymology; Ornithine-Oxo-Acid Transaminase / genetics; RNA, Messenger / genetics; Tretinoin / pharmacology
TL;DR: Testing the hypothesis that RA regulates OAT mRNA expression and enzymatic activity in intestinal epithelial cells concludes that exposure of Caco-2 cells to RA induces OAT expression for increasing ornithine catabolism, which leads to a reduced availability of intracellular Ornithine for polyamine synthesis, thereby decreasing cell proliferation. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2008 journal article

Collagen fiber alignment and biaxial mechanical behavior of porcine urinary bladder derived extracellular matrix

Biomaterials, 29(36), 4775–4782.

By: T. Gilbert*, S. Wognum*, E. Joyce*, D. Freytes*, M. Sacks* & S. Badylak*

author keywords: Extracellular matrix; Scaffold; Collagen fiber alignment; Biaxial mechanical behavior
MeSH headings : Animals; Biomechanical Phenomena; Elastic Modulus; Extracellular Matrix / metabolism; Fibrillar Collagens / metabolism; Mucous Membrane / metabolism; Sus scrofa / metabolism; Urinary Bladder / metabolism
TL;DR: Evaluating the collagen fiber alignment and biaxial mechanical behavior of ECM scaffold material harvested from porcine urinary bladder tunica mucosa and basement membrane found UBML and UBS showed quite different mechanical behavior for the applied loading patterns with UBS showing a much more pronounced toe region. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2008 journal article

Preparation and rheological characterization of a gel form of the porcine urinary bladder matrix

Biomaterials, 29(11), 1630–1637.

author keywords: extracellular matrix; viscoelasticity; rheology; scaffold; gel
MeSH headings : Animals; Cell Adhesion; Cell Proliferation; Cells, Cultured; Extracellular Matrix / metabolism; Extracellular Matrix / ultrastructure; Gels / chemistry; Gels / metabolism; Kinetics; Microscopy, Electron, Scanning; Myocytes, Smooth Muscle / cytology; Rats; Rheology; Swine; Tissue Scaffolds / chemistry; Urinary Bladder / metabolism; Viscosity
TL;DR: An intact form of UBM can be successfully solubilized without purification steps and induced to repolymerize into a gel form of the UBM biologic scaffold material, which supported the adhesion and growth of rat aortic smooth muscle cells when cultured under static in vitro conditions. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2008 journal article

Uniaxial and biaxial properties of terminally sterilized porcine urinary bladder matrix scaffolds

Journal of Biomedical Materials Research Part B: Applied Biomaterials, 84B(2), 408–414.

By: D. Freytes*, R. Stoner* & S. Badylak*

author keywords: sterilization; extracellular matrix; material properties; strength; scaffolds
MeSH headings : Animals; Biocompatible Materials; Extracellular Matrix; Materials Testing; Sterilization; Swine; Tensile Strength; Tissue Scaffolds; Urinary Bladder
TL;DR: The present study showed that the choice of terminal sterilization method affects the structural properties of scaffolds composed of extracellular matrix. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Crossref
Added: August 28, 2020

2008 journal article

Hydrated versus lyophilized forms of porcine extracellular matrix derived from the urinary bladder

Journal of Biomedical Materials Research Part A, 87A(4), 862–872.

By: D. Freytes*, R. Tullius*, J. Valentin*, A. Stewart-Akers* & S. Badylak*

author keywords: extracellular matrix; lyophilization; freeze-drying; scaffold; structural properties; urinary bladder
MeSH headings : Animals; Biocompatible Materials / chemistry; Extracellular Matrix / chemistry; Freeze Drying; Humans; Hydrostatic Pressure; Materials Testing; Mice; NIH 3T3 Cells; Permeability; Stress, Mechanical; Swine; Tissue Engineering / methods; Tissue Scaffolds / chemistry; Urinary Bladder / anatomy & histology; Urinary Bladder / chemistry; Water / chemistry
TL;DR: It is concluded that lyophilization affects the overall in vitro cell growth of NIH 3T3 cells and the ultrastructural morphology of UBM devices, but does not result in significant changes in structural properties. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Crossref
Added: August 28, 2020

2008 journal article

Quantitative Assessment of Breast Lesion Viscoelasticity: Initial Clinical Results Using Supersonic Shear Imaging

Ultrasound in Medicine & Biology, 34(9), 1373–1386.

author keywords: elastography; ultrasound; breast; cancer; acoustic radiation force; shear wave imaging
MeSH headings : Adult; Aged; Breast Cyst / diagnostic imaging; Breast Diseases / diagnostic imaging; Breast Neoplasms / diagnostic imaging; Elasticity; Elasticity Imaging Techniques / methods; Female; Humans; Image Processing, Computer-Assisted; Middle Aged; Sensitivity and Specificity; Stress, Mechanical; Ultrasonography, Mammary / methods; Viscosity; Young Adult
TL;DR: Preliminary clinical results directly demonstrate the clinical feasibility of this new elastography technique in providing quantitative assessment of relative stiffness of breast tissues and give valuable information that is complementary to the B-mode morphologic information. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2008 journal article

Prediction of bone mechanical properties using QUS and pQCT: Study of the human distal radius

Medical Engineering & Physics, 30(6), 761–767.

By: M. Muller*, D. Mitton*, P. Moilanen*, V. Bousson*, M. Talmant* & P. Laugier*

author keywords: QUS; axial transmission; pQCT; radius; bone mechanical properties; Young's modulus; failure load; fracture risk assessment
MeSH headings : Aged; Aged, 80 and over; Biomechanical Phenomena; Bone and Bones / diagnostic imaging; Bone and Bones / physiology; Elasticity; Female; Humans; Imaging, Three-Dimensional; In Vitro Techniques; Male; Middle Aged; Radius / diagnostic imaging; Radius / physiology; Tomography, X-Ray Computed; Ultrasonography
TL;DR: The association of different axial transmission techniques should be able to provide a good prediction of bone mechanical parameters, and should therefore be helpful for fracture risk prediction, according to quasistatic compressive mechanical testing and finite elements modelling. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2008 journal article

Nonlinear ultrasound can detect accumulated damage in human bone

Journal of Biomechanics, 41(5), 1062–1068.

By: M. Muller*, D. Mitton*, M. Talmant*, P. Johnson* & P. Laugier*

author keywords: micro-damage assessment; nonlinear ultrasound; cortical bone; fracture risk; fatigue testing
MeSH headings : Aged; Aged, 80 and over; Female; Femur / diagnostic imaging; Femur / injuries; Humans; Male; Middle Aged; Nonlinear Dynamics; Stress, Mechanical; Ultrasonography
TL;DR: This study represents the first application of the concept of nonlinear dynamic elasticity to human bone, and the results are promising, suggesting the value of further work on this topic. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: August 28, 2020

2008 journal article

A combinatorial approach to microfluidic mixing

Journal of Micromechanics and Microengineering, 18(11), 115019.

By: P. Howell, D. Mott, F. Ligler*, J. Golden, C. Kaplan & E. Oran

TL;DR: A new computational approach to the modeling and design of efficient microfluidic mixers is demonstrated, and the mixers created provide far more rapid mixing than previous designs. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2008 journal article

A Parametric Study of Sample Lysis and DNA Purification Techniques for Use in Automated Devices

Analytical Letters, 41(10), 1701–1719.

By: J. Hu*, J. Erickson*, C. Taitt*, B. Lin*, A. Ligler*, K. Blaney*, A. Malanoski*, F. Ligler*

author keywords: automatable; DNA purification; lysis; sample preparation; solid phase extraction
TL;DR: An optimized protocol has been developed for use with both spiked buffers and nasal wash, and all steps of this protocol are suitable for incorporation into a field-portable, automated sample preparation device. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2008 journal article

Two simple and rugged designs for creating microfluidic sheath flow

Lab on a Chip, 8(7), 1097.

By: P. Howell Jr, J. Golden*, L. Hilliard*, J. Erickson*, D. Mott* & F. Ligler*

MeSH headings : Computer Simulation; Equipment Design; Microfluidic Analytical Techniques / instrumentation
TL;DR: A simple design capable of 2-dimensional hydrodynamic focusing is proposed and successfully demonstrated, which eliminates the need to carefully balance the flow of two or more sheath inlets and easily manufactured using current microfabrication techniques. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2008 journal article

Home diagnostics to music

Nature, 456(7219), 178–179.

By: J. Erickson & F. Ligler*

MeSH headings : Biosensing Techniques / economics; Biosensing Techniques / instrumentation; Biosensing Techniques / methods; Biosensing Techniques / trends; Compact Disks; Diagnostic Equipment / economics; Diagnostic Equipment / trends; Humans; Microfluidic Analytical Techniques / methods
TL;DR: With the latest technology, you could one day perform bioassays on your home compact-disc player, just like in the doctor's surgery. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

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