Works Published in 2016

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Displaying works 1 - 20 of 768 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2016 journal article

Single-platelet nanomechanics measured by high-throughput cytometry

Nature Materials, 16(2), 230–235.

By: D. Myers*, Y. Qiu*, M. Fay*, M. Tennenbaum*, D. Chester n, J. Cuadrado*, Y. Sakurai*, J. Baek* ...

MeSH headings : Blood Coagulation / physiology; Blood Flow Velocity / physiology; Blood Platelets / physiology; Cells, Cultured; Elastic Modulus / physiology; Flow Cytometry / methods; Hardness / physiology; Humans; Mechanotransduction, Cellular / physiology; Nanoparticles / chemistry; Platelet Activation / physiology; Platelet Adhesiveness / physiology
TL;DR: A high-throughput hydrogel based platelet-contraction cytometer is reported that quantifies single-platelet contraction forces in different clot microenvironments and shows that platelets, via the Rho/ROCK pathway, synergistically couple mechanical and biochemical inputs to mediate contraction. (via Semantic Scholar)
Source: Crossref
Added: May 17, 2024

2016 chapter

Equine ocular examination basic techniques

In B. Gilger (Ed.), Equine Ophthalmology (pp. 1–39).

By: R. Stoppini & B. Gilger*

Ed(s): B. Gilger*

Sources: Crossref, NC State University Libraries
Added: January 29, 2024

2016 journal article

0387 Daily rumination time in Italian Holstein cows: Heritability and correlation with milk production

Journal of Animal Science, 94(suppl_5), 187–188.

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 27, 2024

2016 journal article

028 The use of alternative genomic metrics in swine nucleus herds to manage the diversity of purebred and crossbred animals

Journal of Animal Science, 94(suppl_2), 13–13.

By: J. Howard n, F. Tiezzi n, Y. Huang, K. Gray & C. Maltecca n

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 27, 2024

2016 journal article

029 Mitigating the effect of seasonality on sow reproductive performance using genetic selection

Journal of Animal Science, 94(suppl_2), 14–14.

By: M. Bryan n, C. Maltecca n, K. Gray, Y. Huang & F. Tiezzi n

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 27, 2024

2016 journal article

0301 A combined coalescence forward in time simulator software for pedigreed populations undergoing selection for complex traits

Journal of Animal Science, 94(suppl_5), 143–144.

By: J. Howard n, F. Tiezzi n, J. Pryce & C. Maltecca n

Sources: Crossref, NC State University Libraries
Added: January 27, 2024

2016 journal article

Expanding the substrate scope and reactivity of cytochrome P450 OleT

Biochemical and Biophysical Research Communications, 476(4), 462–466.

By: C. Hsieh* & T. Makris*

Contributors: C. Hsieh* & T. Makris*

TL;DR: Spectroscopic and turnover studies show that the mutation eliminates the binding and metabolism of prototypical fatty acid substrates, but permits the oxidation of a broad range of inert hydrocarbon substrates. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: ORCID
Added: December 12, 2023

2016 journal article

Catalytic strategy for carbon-carbon bond scission by the cytochrome p450 olet

Proceedings of the National Academy of Sciences of the United States of America, 113(36), 10049–10054.

By: J. Grant*, M. Mitchell* & T. Makris*

Contributors: J. Grant*, M. Mitchell* & T. Makris*

TL;DR: Rapid kinetics studies reveal two critical reaction cycle intermediates that define the catalytic strategy used by OleT and highlight the functional versatility of P450 enzymes. (via Semantic Scholar)
Source: ORCID
Added: December 12, 2023

2016 journal article

Mixed regiospecificity compromises alkene synthesis by a cytochrome P450 peroxygenase from Methylobacterium populi

Journal of Inorganic Biochemistry, 158, 11–16.

By: J. Amaya*, C. Rutland* & T. Makris*

Contributors: J. Amaya*, C. Rutland* & T. Makris*

TL;DR: It is shown that a second CYP152, CYP-MP from Methylobacterium populi ATCC BAA 705, also catalyzes oxidative substrate decarboxylation, suggesting an importance of substrate coordination for regulating alkene production. (via Semantic Scholar)
Source: ORCID
Added: December 12, 2023

2016 journal article

The respiratory DC/macrophage network at steady-state and upon influenza infection in the swine biomedical model

Mucosal Immunology, 9(4), 835–849.

By: P. Maisonnasse*, E. Bouguyon*, G. Piton*, A. Ezquerra*, C. Urien*, C. Deloizy*, M. Bourge*, J. Leplat* ...

MeSH headings : Animals; Antigens, CD / metabolism; Cells, Cultured; Dendritic Cells / immunology; Dendritic Cells / virology; Disease Models, Animal; Humans; Influenza, Human / immunology; Lectins, C-Type / metabolism; Lymphocyte Activation; Macrophages / immunology; Macrophages / virology; Macrophages, Alveolar / immunology; Macrophages, Alveolar / virology; Mannose-Binding Lectins / metabolism; Mice; Orthomyxoviridae / immunology; Orthomyxoviridae Infections / immunology; Receptors, IgE / metabolism; Respiratory System / immunology; Swine; Th1 Cells / immunology; Th2 Cells / immunology
TL;DR: By unraveling the extended similarities of the porcine and human lung dendritic cells/macrophages networks, this work highlights the relevance of pig, both as an exploratory model of DC/Mθ functions and as a model for human inflammatory lung pathologies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 31, 2023

2016 journal article

Improving wound healing through the use of tetrazine-modified alginate

The FASEB Journal, 30(Supplement 1), 1177.10–1177.10.

By: E. De Leon Peralta*, Y. Brudno*, B. Kwee* & D. Mooney*

Event: Experimental Biology 2016 Meeting

TL;DR: The hypothesis is that tetrazine acts directly on endothelial cells to induce angiogenesis and also activates immune cells that are proangiogenic, which may lead to a novel method for treating people with ischemic diseases. (via Semantic Scholar)
Sources: NC State University Libraries, NC State University Libraries
Added: July 22, 2023

2016 chapter

Microfluidic Platforms for Quantitative Biology Studies in Model Organisms

In C. Lu & S. S. Verbridge (Eds.), Microfluidic Methods for Molecular Biology (pp. 1–18).

By: D. Porto*, T. Rouse*, A. San-Miguel* & H. Lu*

Contributors: D. Porto*, T. Rouse*, A. San-Miguel* & H. Lu*

Ed(s): C. Lu* & S. Verbridge

Event: at Cham

TL;DR: An overview of the current state of the field, the impacts of microfluidics in model organism research, and the outlook, challenges, and opportunities for the future is provided. (via Semantic Scholar)
Source: ORCID
Added: May 31, 2023

2016 journal article

Hepatitis C in North Carolina: Two Epidemics With One Public Health Response

North Carolina Medical Journal, 77(3), 190–192.

By: S. Rhea*, A. Fleischauer*, E. Foust* & M. Davies*

MeSH headings : Hepatitis C / diagnosis; Hepatitis C / epidemiology; Hepatitis C / therapy; Humans; North Carolina / epidemiology; Public Health Practice
TL;DR: An emerging epidemic of acute HCV infection has been recognized among young persons who inject drugs and live in rural, resource-poor areas, and new hot spots have been identified in central Appalachian states. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: May 24, 2023

2016 journal article

Hepatitis B Reverse Seroconversion and Transmission in a Hemodialysis Center: A Public Health Investigation and Case Report

American Journal of Kidney Diseases, 68(2), 292–295.

By: S. Rhea*, A. Moorman, R. Pace*, V. Mobley*, J. MacFarquhar*, E. Robinson*, T. Hayden, H. Thai ...

MeSH headings : Aged, 80 and over; Ambulatory Care Facilities; Female; Hepatitis B / blood; Hepatitis B / transmission; Hepatitis B Antibodies / blood; Humans; Public Health; Renal Dialysis; Seroconversion
TL;DR: HBV transmission occurred after an HIV-positive hemodialysis patient with transplant-related immunosuppression experienced HBV reverse seroconversion and reactivation, and providers should be aware of this possibility, and maintain stringent infection control. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: May 24, 2023

2016 journal article

Association of breed and histopathological grade in canine mast cell tumours.

Veterinary and Comparative Oncology.

By: H. Mochizuki n, A. Motsinger-Reif n, C. Bettini, S. Moroff & M. Breen n

MeSH headings : Age Factors; Animals; Dog Diseases / etiology; Dog Diseases / pathology; Dogs; Female; Male; Mastocytosis, Cutaneous / etiology; Mastocytosis, Cutaneous / pathology; Mastocytosis, Cutaneous / veterinary; Retrospective Studies; Risk Factors; Sex Factors; Skin Neoplasms / etiology; Skin Neoplasms / pathology; Skin Neoplasms / veterinary; Species Specificity
TL;DR: The data indicate that the proportion of high-grade tumours increases with advancing age, and that male and intact dogs have increased odds of developing high- grade tumours, and a genetic association for the development ofhigh-grade MCTs is suggested. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: May 23, 2023

2016 journal article

Highlighting Cancer Cells with Halochromic Switches

ACS Sensors, 2(1), 92–101.

TL;DR: The structural design for the covalent integration of activatable signaling units and targeting ligands within the same nanostructured assembly together with the photophysical properties engineered into the emissive components offer the opportunity to highlight cancer cells selectively with high brightness and optimal contrast. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2016 journal article

A Photoswitchable Fluorophore for the Real-Time Monitoring of Dynamic Events in Living Organisms

Chemistry - A European Journal, 22(42), 15027–15034.

MeSH headings : Animals; Drosophila melanogaster; Fluorescent Dyes / chemistry; Photochemical Processes
TL;DR: The synthesis of a photoactivatable fluorophore with optimal photochemical and photophysical properties for the real-time tracking of motion in vivo can evolve into a general chemical tool to monitor dynamic processes in living biological specimens. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2016 journal article

Supramolecular delivery of fluorescent probes in developing embryos

RSC Adv., 6(76), 72756–72760.

TL;DR: Self-assembling nanocarriers of amphiphilic polymers encapsulate hydrophobic fluorophores in their hydrophilic interior and, upon injection in Drosophila melanogaster embryos, release their cargo into the cellular blastoderm. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2016 conference paper

Supramolecular nanocarriers with photoresponsive cargo

In W. J. Parak, M. Osinski, & X.-J. Liang (Eds.), Colloidal Nanoparticles for Biomedical Applications XI.

Ed(s): W. Parak, M. Osinski & X. Liang

TL;DR: Operating principles to solubilize and operate photoswitchable fluorophores in aqueous environments with the aid of supramolecular nanocarriers can lead to valuable protocols to image specimens with subdiffraction resolution and to monitor dynamic events noninvasively. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2016 journal article

A pH-Gated Photocage

Advanced Optical Materials, 5.

UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: ORCID
Added: March 13, 2023

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