Immunology

Works Published in 2002

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2002 journal article

Involvement of lipopolysaccharide related receptors and nuclear factor kappa B in differential expression of inducible nitric oxide synthase in chicken macrophages from different genetic backgrounds

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 88(3-4), 149–161.

By: N. Dil n & M. Qureshi n

author keywords: chicken macrophage; genetic lines; iNOS; CD14; TLR4; NF kappa B
MeSH headings : Animals; Chickens / genetics; Chickens / immunology; Drosophila Proteins; Enzyme Induction / drug effects; Flow Cytometry; Gene Expression Regulation, Enzymologic / drug effects; Lipopolysaccharide Receptors / biosynthesis; Lipopolysaccharide Receptors / genetics; Lipopolysaccharide Receptors / metabolism; Lipopolysaccharides / pharmacology; Macrophages / drug effects; Macrophages / enzymology; Macrophages / metabolism; Membrane Glycoproteins / biosynthesis; Membrane Glycoproteins / metabolism; NF-kappa B / antagonists & inhibitors; NF-kappa B / metabolism; Nitric Oxide Synthase / biosynthesis; Nitric Oxide Synthase / drug effects; Nitric Oxide Synthase / genetics; Nitric Oxide Synthase Type II; Nitrites / metabolism; Receptors, Cell Surface / biosynthesis; Receptors, Cell Surface / metabolism; Signal Transduction / drug effects; Toll-Like Receptor 4; Toll-Like Receptors; Transcriptional Activation
TL;DR: A differential and perhaps more stronger LPS-mediated signaling via CD14, TLR4 and NF kappa B is responsible for the heightened iNOS gene induction in K-strain (hyper- responder) macrophages than in GB2 (hypo-responder) chickens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Interactions of poult enteritis and mortality syndrome-associated reovirus with various cell types in vitro

POULTRY SCIENCE, 81(11), 1661–1667.

By: C. Heggen-Peay n, M. Cheema n, R. Ali n, K. Schat n & M. Qureshi n

author keywords: poult enteritis and mortality syndrome; reovirus; replication; immune response
MeSH headings : Animals; Antigens, Viral / analysis; B-Lymphocytes / metabolism; B-Lymphocytes / virology; Cell Line; Cells, Cultured; Chickens; Cytopathogenic Effect, Viral; Interleukin-1 / genetics; Interleukin-1 / metabolism; Liver / cytology; Liver / virology; Macrophages / metabolism; Macrophages / virology; Microscopy, Electron / veterinary; Orthoreovirus, Avian / growth & development; Orthoreovirus, Avian / immunology; Orthoreovirus, Avian / pathogenicity; Poult Enteritis Mortality Syndrome / metabolism; Poult Enteritis Mortality Syndrome / virology; Poultry Diseases / metabolism; Poultry Diseases / virology; RNA, Messenger / metabolism; Reoviridae Infections / veterinary; Reoviridae Infections / virology; Specific Pathogen-Free Organisms; T-Lymphocytes / metabolism; T-Lymphocytes / virology; Tumor Cells, Cultured; Turkeys; Virus Replication
TL;DR: It is demonstrated that ARV-CU98 actively infects and replicates in LMH cells, but not in lymphocytes or macrophages, suggesting that the liver may be a target and site of replication of ARV -CU98 in poults experiencing PEMS. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

The effects of cAMP modulation upon the adhesion and respiratory burst activity of immune complex-stimulated equine neutrophils

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 88(1-2), 65–77.

By: C. Chilcoat n, K. Rowlingson n & S. Jones n 

author keywords: neutrophil; cAMP; adhesion; integrin; immune complex
MeSH headings : Adrenergic beta-Agonists / pharmacology; Animals; Antigen-Antibody Complex / immunology; Cell Adhesion / immunology; Clenbuterol / pharmacology; Cyclic AMP / antagonists & inhibitors; Cyclic AMP / immunology; Cyclic AMP-Dependent Protein Kinases / immunology; Horses / blood; Horses / immunology; Isoproterenol / pharmacology; Neutrophils / cytology; Neutrophils / immunology; Pentoxifylline / pharmacology; Phosphodiesterase Inhibitors / pharmacology; Respiratory Burst / immunology; Rolipram / pharmacology
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Thymocyte and peripheral blood T lymphocyte subpopulation changes in piglets following in utero infection with porcine reproductive and respiratory syndrome virus

VIROLOGY, 302(2), 363–372.

By: W. Feng n, M. Tompkins n, J. Xu n, T. Brown n, S. Laster n, H. Zhang*, M. McCaw n

author keywords: PRRSV; thymus; thymocyte; T lymphocyte
MeSH headings : Animals; Animals, Newborn; Female; Infectious Disease Transmission, Vertical; Leukocytes, Mononuclear / immunology; Lymphocyte Count; Porcine Reproductive and Respiratory Syndrome / immunology; Porcine Reproductive and Respiratory Syndrome / virology; Porcine respiratory and reproductive syndrome virus / immunology; Pregnancy; Pregnancy, Animal; Swine; Swine Diseases / immunology; Swine Diseases / virology; T-Lymphocyte Subsets / immunology; Thymus Gland / cytology; Thymus Gland / immunology; Uterus / virology
TL;DR: It is shown that the number of thymocytes undergoing apoptosis was increased twofold in piglets infected with PRRSV and this results help explain the dramatic immunosuppression observed in neonatal animals infected in utero withPRRSV. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

IgE is present on peripheral blood monocytes and B cells in normal dogs and dogs with atopic dermatitis but there is no correlation with serum IgE concentrations

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 85(3-4), 225–232.

By: H. Jackson n, S. Orton n & B. Hammerberg n

author keywords: IgE; canine PBMCs; canine atopic dermatitis
MeSH headings : Animals; Antigens, CD1 / blood; B-Lymphocytes / immunology; B-Lymphocytes / metabolism; Dermatitis, Atopic / blood; Dermatitis, Atopic / immunology; Dermatitis, Atopic / veterinary; Dog Diseases / blood; Dog Diseases / immunology; Dogs / blood; Dogs / immunology; Female; Flow Cytometry / veterinary; Glycoproteins / blood; Immunoglobulin E / blood; Immunoglobulin E / immunology; Lipopolysaccharide Receptors / blood; Male; Monocytes / immunology; Monocytes / metabolism; Receptors, Complement 3d / blood
TL;DR: Canine AD is associated with more variability in circulating monocyte numbers and lower numbers of monocytes expressing IgE than control dogs, and there is no correlation between circulating and cell bound IgE in any of the leucocyte populations studied. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Isolation of a reovirus from poult enteritis and mortality syndrome and its pathogenicity in turkey poults

AVIAN DISEASES, 46(1), 32–47.

By: C. Heggen-Peay n, M. Qureshi n, F. Edens n, B. Sherry*, P. Wakenell, . PH O'Connell, K. Schat*

author keywords: poult enteritis and mortality syndrome; reovirus; turkey; fecal filtrate
TL;DR: It is demonstrated that ARV-CU98 does cause some of the clinical signs in PEMS, including intestinal alterations and significantly lower relative bursa and liver weights. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Choroid plexus macrophages proliferate and release toxic factors in response to feline immunodeficiency virus

JOURNAL OF NEUROVIROLOGY, 8(3), 225–239.

By: D. Bragg*, L. Hudson n, Y. Liang n, M. Tompkins n, A. Fernandes* & R. Meeker  n

author keywords: human immunodeficiency virus; brain; AIDS; neural culture; neurotoxicity
MeSH headings : Animals; CD18 Antigens / analysis; CD40 Ligand / pharmacology; Cats; Cell Division / drug effects; Cell Division / immunology; Cells, Cultured; Cerebral Cortex / cytology; Choroid Plexus / cytology; Choroid Plexus / immunology; Choroid Plexus / virology; Culture Media, Conditioned / pharmacology; Cytotoxins / immunology; Cytotoxins / metabolism; Feline Acquired Immunodeficiency Syndrome / immunology; Feline Acquired Immunodeficiency Syndrome / virology; Immunodeficiency Virus, Feline / immunology; In Vitro Techniques; Macrophages / chemistry; Macrophages / cytology; Macrophages / virology; Neurons / virology; Specific Pathogen-Free Organisms
TL;DR: The results suggest that lentiviral infection of the choroid plexus can induce a toxic inflammatory response that is fueled by local macrophage proliferation and may contribute to an inflammatory cascade in the brain that progresses independently of systemic and CSF viral load. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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