Immunology

Works Published in 2012

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Displaying all 2 works

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2012 journal article

Administration of Fozivudine Tidoxil as a Single-Agent Therapeutic during Acute Feline Immunodeficiency Virus Infection Does Not Alter Chronic Infection

Viruses, 4(6), 954–962.

By: M. Miller n & J. Fogle n

author keywords: acquired immunodeficiency syndrome; lentivirus; FIV; antiretroviral therapy (ART); Zidovudine; Fozivudine
MeSH headings : Animals; Anti-HIV Agents / administration & dosage; CD4-CD8 Ratio; Cat Diseases / drug therapy; Cats; Feline Acquired Immunodeficiency Syndrome / drug therapy; Feline Acquired Immunodeficiency Syndrome / virology; Lipids / administration & dosage; Lymphocyte Count; Treatment Outcome; Viral Load; Viremia / virology; Zidovudine / administration & dosage; Zidovudine / analogs & derivatives
TL;DR: It is suggested that treatment with a single agent anti-retroviral drug during acute lentivirus infection does not significantly alter viral load and immune function during the chronic, asymptomatic stage of infection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Crossref
Added: July 20, 2019

2012 journal article

A cell-based MHC stabilization assay for the detection of peptide binding to the canine classical class I molecule, DLA-88

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 150(3-4), 206–212.

By: P. Ross n, J. Holmes n, G. Gojanovich n & P. Hess n 

author keywords: Canine; CD8(+) T lymphocytes; MHC; Peptides/epitopes
MeSH headings : Animals; Biological Assay / methods; Biological Assay / veterinary; CD8-Positive T-Lymphocytes / metabolism; Cell Line, Tumor; Cell Membrane; Dogs / metabolism; Epitopes; Gene Expression Regulation / physiology; Histocompatibility Antigens Class I / chemistry; Histocompatibility Antigens Class I / metabolism; Mice; Protein Binding; Protein Subunits
TL;DR: The potential to use RMA-S cells transfected with canine alleles as a tool for CTL epitope discovery in this species is demonstrated, and the high false positive rate with this analysis ideally requires binding confirmation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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