Works Published in 2013

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Displaying all 8 works

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2013 journal article

The Effect of an Oral Probiotic Containing Lactobacillus, Bifidobacterium, and Bacillus Species on the Vaginal Microbiota of Spayed Female Dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, 27(6), 1368–1371.

author keywords: Lactic acid-producing bacteria; Recurrent urinary tract infection
MeSH headings : Animals; Bacillus / genetics; Bacillus / isolation & purification; Bifidobacterium / genetics; Bifidobacterium / isolation & purification; Dog Diseases / microbiology; Dog Diseases / prevention & control; Dogs; Female; Lactobacillus / genetics; Lactobacillus / isolation & purification; Microbiota / genetics; Probiotics / pharmacology; Sequence Analysis, DNA; Urinary Tract Infections / microbiology; Urinary Tract Infections / prevention & control; Urinary Tract Infections / veterinary; Vagina / microbiology
TL;DR: Administration of this oral probiotic supplement for a 2- or 4-week period did not increase the prevalence of vaginal LAB in dogs and Enterococcus canintestini was the most common LAB isolated from all dogs in this study, although it was not included in the probiotics supplement. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Lymphoma Immunophenotype of Dogs Determined by Immunohistochemistry, Flow Cytometry, and Polymerase Chain Reaction for Antigen Receptor Rearrangements

Journal of Veterinary Internal Medicine, 27(6), 1509–1516.

By: L. Thalheim n, L. Williams n, L. Borst n, J. Fogle n & S. Suter n

author keywords: Cancer; Flow cytometry; Lineage; Lymph nodes; Specificity
MeSH headings : Animals; Area Under Curve; DNA / chemistry; DNA / genetics; Dog Diseases / immunology; Dogs; Female; Flow Cytometry / veterinary; Immunohistochemistry / veterinary; Immunophenotyping / methods; Immunophenotyping / veterinary; Lymph Nodes / immunology; Lymphoma / genetics; Lymphoma / immunology; Male; Polymerase Chain Reaction / veterinary; Receptors, Antigen / genetics; Receptors, Antigen / immunology; Reproducibility of Results; Retrospective Studies; Sensitivity and Specificity
TL;DR: Flow cytometry is superior to PARR in correctly predicting immunophenotypes when evaluating lymph nodes from dogs already diagnosed with B- or T-cell LSA and if fresh samples are not available for FC, PARR is an acceptable assay for determination of immunophenotype given its high specificity. (via Semantic Scholar)
Sources: Web Of Science, Crossref
Added: August 6, 2018

2013 journal article

Infection with Feline Immunodeficiency Virus Directly Activates CD4+ CD25+ T Regulatory Cells

Journal of Virology, 87(16), 9373–9378.

MeSH headings : Animals; CD4-Positive T-Lymphocytes / chemistry; CD4-Positive T-Lymphocytes / immunology; Cats; Cells, Cultured; Gene Expression Profiling; Immunodeficiency Virus, Feline / immunology; Immunosuppression Therapy; Interleukin-2 Receptor alpha Subunit / analysis; T-Lymphocyte Subsets / chemistry; T-Lymphocyte Subsets / immunology; T-Lymphocytes, Regulatory / chemistry; T-Lymphocytes, Regulatory / immunology
TL;DR: In vitro feline immunodeficiency virus (FIV) infection, but not UV-inactivated virus, activates Treg cells as measured by immunosuppressive function and upregulation of GARP, FoxP3, and membrane-bound transforming growth factor β (TGF-β). (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref
Added: August 6, 2018

2013 journal article

Characterization and allelic variation of the transporters associated with antigen processing (TAP) genes in the domestic dog (Canis lupus familiaris)

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 41(4), 578–586.

By: G. Gojanovich n, P. Ross n, S. Holmer n, J. Holmes n & P. Hess n

author keywords: Alleles; Canine; Immunology; Splice variants; Transporter associated with antigen processing
MeSH headings : ATP-Binding Cassette Transporters / genetics; Alleles; Amino Acid Sequence; Animals; Antigen Presentation / genetics; Cell Line; Dogs; Genetic Variation; Histocompatibility Antigens Class I / genetics; Humans; Mice; Molecular Sequence Data; Phylogeny; Promoter Regions, Genetic; Protein Isoforms; Wolves / genetics
TL;DR: The promoter and coding regions of the canine TAP1 and TAP2 genes, which encode the homologous subunits forming the TAP heterodimer, are reported, which should prove useful in investigating the association of specific TAP defects or alleles with immunity to intracellular pathogens and cancer in dogs. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Polymorphisms and tissue expression of the feline leukocyte antigen class I loci FLAI-E, FLAI-H, and FLAI-K

IMMUNOGENETICS, 65(9), 675–689.

By: J. Holmes n, S. Holmer n, P. Ross n, A. Buntzman*, J. Frelinger* & P. Hess n

author keywords: Cat; Major histocompatibility complex; Polymorphism; Classical class I genes
MeSH headings : Amino Acid Sequence; Animals; CD8-Positive T-Lymphocytes / immunology; Cats / genetics; Cats / immunology; Cloning, Molecular; Complementarity Determining Regions / genetics; Genotype; Histocompatibility Antigens Class I / chemistry; Histocompatibility Antigens Class I / genetics; Models, Animal; Molecular Sequence Data; Polymorphism, Single Nucleotide; Sequence Alignment; Viruses / immunology
TL;DR: Alleles could be assigned to a specific locus with reasonable confidence, although there was evidence of potentially confounding interlocus recombination between FLAI-E andFLAI-K, and hypervariable regions across these genes permitted the assignment of names to both novel and established alleles. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Human intravenous immunoglobulin (hIVIG) inhibits anti-CD32 antibody binding to canine DH82 cells and canine monocytes in vitro

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 151(3-4), 229–234.

By: T. Sibley, M. Miller* & J. Fogle*

author keywords: Fc gamma receptor; CD16; CD32; Intravenous immunoglobulin
MeSH headings : Animals; Antibodies, Blocking / metabolism; Antibodies, Heterophile / metabolism; Antigen-Antibody Complex / metabolism; Antigen-Antibody Reactions; Cell Line; Dogs / immunology; Humans; Immunoglobulins, Intravenous / metabolism; Monocytes / immunology; Receptors, IgG / antagonists & inhibitors; Receptors, IgG / metabolism
TL;DR: This is the first report to demonstrate Fc(γ) receptors CD16 and CD32 expression on canine monocytes and in vitro CD32 binding by human IgG, which may represent one of the immunomodulatory mechanisms of hIVIG. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Feline Glycoprotein A Repetitions Predominant Anchors Transforming Growth Factor Beta on the Surface of Activated CD4(+)CD25(+) Regulatory T Cells and Mediates AIDS Lentivirus-Induced T Cell Immunodeficiency

AIDS RESEARCH AND HUMAN RETROVIRUSES, 29(4), 641–651.

MeSH headings : Amino Acid Sequence; Animals; Cats; Feline Acquired Immunodeficiency Syndrome / etiology; Feline Acquired Immunodeficiency Syndrome / immunology; Glycoproteins / genetics; Glycoproteins / immunology; Glycoproteins / metabolism; Humans; Immune Tolerance; Immunodeficiency Virus, Feline / immunology; Immunodeficiency Virus, Feline / pathogenicity; Membrane Proteins / genetics; Membrane Proteins / immunology; Membrane Proteins / metabolism; Models, Molecular; Molecular Sequence Data; Multiprotein Complexes / metabolism; Protein Conformation; RNA, Messenger / genetics; RNA, Messenger / metabolism; Sequence Homology, Amino Acid; Species Specificity; T-Lymphocytes, Regulatory / immunology; Transforming Growth Factor beta / metabolism
TL;DR: It is demonstrated that the GARP(+) Treg cells from FIV-infected cats suppress T helper cells in vivo and that blocking GARP or TGFb eliminates this suppression. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

CD8(+) clonality is associated with prolonged acute plasma viremia and altered mRNA cytokine profiles during the course of Feline Immunodeficiency Virus infection

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 152(3-4), 200–208.

author keywords: FIV; AIDS; CTL; CD8(+) clonality; PARR
MeSH headings : Animals; CD8 Antigens / metabolism; CD8-Positive T-Lymphocytes / immunology; Cat Diseases / genetics; Cat Diseases / immunology; Cats; Clonal Selection, Antigen-Mediated / genetics; Cytokines / genetics; Gene Rearrangement, T-Lymphocyte; Immunodeficiency Virus, Feline; Lentivirus Infections / genetics; Lentivirus Infections / immunology; Lentivirus Infections / veterinary; Male; RNA, Messenger / genetics; RNA, Messenger / metabolism; Transcriptome; Viremia / genetics; Viremia / immunology; Viremia / veterinary
TL;DR: Using PARR to assess changes in CD8(+) clonality during the progression from acute to chronic FIV infection may help to better characterize the factors which contribute to CD8 (+) anergy and lentiviral persistence. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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