Works Published in 2017
Displaying works 21 - 40 of 78 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2017 chapter
Acillea millefolium: Re-Exploring herbal remides for combating malaria
Source: ORCID
Added: November 12, 2019
2017 journal article
∝-amylase and ∝- glucosidase inhibitory activities of phenolic extracts from Eucalyptus grandis x E. urophylla bark
Journal of Chemistry.
downloads.hindawi.com (publisher PDF)
Source: ORCID
Added: November 12, 2019
2017 journal article
Pendulaosides A and B. Two acylated triterpenoid saponins from Harpullia pendula seed extract
Phytochemistry Letters.
Source: ORCID
Added: November 12, 2019
2017 journal article
One-step isolation of carnosic acid and carnosol from rosemary by centrifugal partition chromatography
Journal of Separation Science.
author keywords: carnosic acid; carnosol; centrifugal partition chromatography; Rosmarinus officinalis
Source: ORCID
Added: November 12, 2019
2017 journal article
Metabolic effects of berries with structurally diverse anthocyanins
International Journal of Molecular Sciences.
MeSH headings : Animal Feed; Animals; Anthocyanins / chemistry; Anthocyanins / metabolism; Body Composition; Body Weight; Chromatography, High Pressure Liquid; Dietary Supplements; Feces / chemistry; Fruit / metabolism; Gastrointestinal Microbiome; Glucose / metabolism; Humans; Insulin Resistance; Mice; Molecular Structure; Oxygen Consumption
Source: ORCID
Added: November 12, 2019
2017 journal article
Inter- and intra-seasonal changes in anthocyanin accumulation and global metabolite profiling of six blueberry genotypes
Journal of Food Composition and Analysis.
Source: ORCID
Added: November 12, 2019
2017 journal article
α-Amylase and α-Glucosidase Inhibitory Activities of Phenolic Extracts from Eucalyptus grandis × E. urophylla Bark
Journal of Chemistry, 2017, 1–7.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Crossref
Added: November 12, 2019
2017 journal article
Synthesis of apo-13- and apo-15-lycopenoids, cleavage products of lycopene that are retinoic acid antagonists
Journal of Lipid Research, 58(5), 1021–1029.
MeSH headings : Carotenoids / chemical synthesis; Carotenoids / chemistry; Carotenoids / metabolism; Carotenoids / pharmacology; Chemistry Techniques, Synthetic; Gene Expression Regulation / drug effects; Hep G2 Cells; Humans; Lycopene; Molecular Docking Simulation; Protein Conformation; Receptors, Retinoic Acid / antagonists & inhibitors; Receptors, Retinoic Acid / chemistry; Receptors, Retinoic Acid / metabolism
TL;DR:
The “first half” putative oxidative cleavage products of the symmetrical lycopene have been synthesized and isothermal titration calorimetry studies reveal that apo-13-lycopenone acts as an antagonist of RAR by inhibiting coactivator recruitment to the receptor.
(via Semantic Scholar)
Sources: NC State University Libraries, ORCID
Added: February 8, 2019
2017 journal article
Anthocyanins in metabolic health and disease
Nutrigenomics and Proteomics in Health and Disease: towards a Systems-Level Understanding of Gene-Diet Interactions, 2nd Edition, 92–124.
Source: NC State University Libraries
Added: August 6, 2018
2017 chapter
Epigenetic Reprogramming During Plant Reproduction
In Plant Epigenetics (pp. 405–425).
author keywords: Epigenetics; Reprogramming; Gametogenesis; Reproduction; DNA Methylation; Active DNA Demethylation; Chromatin Remodeling; Transgenerational Inheritance; siRNAs
TL;DR:
In Arabidopsis, gene imprinting is a consequence of a large-scale epigenetic reprogramming via DEMETER-mediated active DNA demethylation during gametogenesis, believed to be critical for the maintenance of trans-generational epigenome integrity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2017 journal article
Novel Artificial Tears Containing Cross-Linked Hyaluronic Acid: An In Vitro Re-Epithelialization Study
MOLECULES, 22(12).
author keywords: anti-inflammatory; artificial tears; corneal epithelium; cyclin D1; dry eye syndrome; HA; HA-CL; IL-8; re-epithelialization
MeSH headings : Analysis of Variance; Biomarkers; Cell Line; Cell Survival; Cyclin D1 / metabolism; Drug Stability; Dry Eye Syndromes; Epithelium, Corneal / drug effects; Humans; Hyaluronic Acid / analysis; Hyaluronic Acid / chemistry; Hydrogen-Ion Concentration; Lubricant Eye Drops / analysis; Lubricant Eye Drops / chemical synthesis; Lubricant Eye Drops / chemistry; Lubricant Eye Drops / pharmacology; Re-Epithelialization / drug effects; Viscosity; Wound Healing / drug effects
TL;DR:
An in vitro evaluation of the re-epithelialization ability of two different preparations containing a recently synthetized HA cross-linked with urea showed no cellular toxicity, a slight decrease in IL-8 release, and restoration of epithelium integrity when the wounded 3D model was treated with S1 and S2.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Polyphenols isolated from Acacia mearnsii bark with anti-inflammatory and carbolytic enzyme inhibitory activities
Chinese Journal of Natural Medicines, 15(11), 816–824.
Contributors: J. Xiong n , M. Grace n , D. Esposito n , S. Komarnytsky n , F. Wang * & M. Lila n
author keywords: Acacia mearnsii; Proanthocyanidins; Anti-inflammatory; alpha-Amylase; alpha-Glucosidase
MeSH headings : Acacia / chemistry; Animals; Anti-Inflammatory Agents / isolation & purification; Anti-Inflammatory Agents / pharmacology; Carbohydrate Metabolism / drug effects; Glycoside Hydrolase Inhibitors / pharmacology; Inflammation / metabolism; Interleukin-1beta / metabolism; Lipopolysaccharides; Macrophages / drug effects; Mice; Nitric Oxide / metabolism; Nitric Oxide Synthase Type II / metabolism; Plant Bark / chemistry; Plant Extracts / chemistry; Plant Extracts / pharmacology; Polyphenols / isolation & purification; Polyphenols / pharmacology; Proanthocyanidins / pharmacology; RAW 264.7 Cells; alpha-Amylases / antagonists & inhibitors; alpha-Glucosidases / metabolism
TL;DR:
Polyphenols isolated from Acacia mearnsii bark crude extract and fractions obtained by high-speed counter-current chromatography and evaluated their anti-inflammatory and carbolytic enzymes (α-glucosidase and α-amylase) inhibitory activities showed significant activities against reactive oxygen species, nitric oxide production, and expression of pro-inflammatory genes interleukin-1β.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2017 journal article
Mango Supplementation Has No Effects on Inflammatory Mediators in Obese Adults
NUTRITION AND METABOLIC INSIGHTS, 10.
author keywords: Mangoes; obesity; anthropometrics; anti-inflammatory markers; lipids
TL;DR:
It is demonstrated that 12-week consumption of freeze-dried mango by obese individuals has no impact on obesity-related inflammation and relationships were found between adiponectin and high-density lipoprotein cholesterol and between leptin and fat mass.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Retention of mitochondria in mature human red blood cells as the result of autophagy impairment in Rett syndrome
Scientific Reports, 7.
MeSH headings : Animals; Autophagosomes / pathology; Autophagy / genetics; Cells, Cultured; Cerebellum / pathology; Disease Models, Animal; Erythrocytes / cytology; Erythrocytes / metabolism; Erythrocytes / ultrastructure; Female; Fibroblasts; Healthy Volunteers; Humans; Male; Methyl-CpG-Binding Protein 2 / genetics; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Mutation; Primary Cell Culture; Protein Aggregates / genetics; Rett Syndrome / blood; Rett Syndrome / genetics; Rett Syndrome / pathology; Sequestosome-1 Protein / metabolism
TL;DR:
It is proposed that a defective autophagy could be involved in the RTT clinical phenotype, which introduces new molecular perspectives in the pathogenesis of the syndrome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
5. Gender Equality
(Web of Science)
Sources: NC State University Libraries, ORCID
Added: August 6, 2018
2017 journal article
Potassium Ascorbate with Ribose: Promising Therapeutic Approach for Melanoma Treatment
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2017.
MeSH headings : Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Antineoplastic Agents / therapeutic use; Ascorbic Acid / chemistry; Cell Line, Tumor; Cell Proliferation / drug effects; Cell Survival / drug effects; Connexin 43 / genetics; Connexin 43 / metabolism; Humans; Melanoma / drug therapy; Melanoma / pathology; Microscopy, Electron, Scanning; Potassium / chemistry; Ribose / chemistry; Spheroids, Cellular / drug effects; Spheroids, Cellular / ultrastructure
TL;DR:
The results suggest that PAR could be used as a safe adjuvant approach in support to conventional therapies for the treatment of melanoma.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Phytoecdysteroid-enriched quinoa seed leachate enhances healthspan and mitochondrial metabolism in Caenorhabditis elegans
JOURNAL OF FUNCTIONAL FOODS, 37, 1–7.
author keywords: Aging; C elegans; Physical performance; Phytoecdysteroid; Respiration; Quinoa
TL;DR:
Data suggest that quinoa supplementation slows C. elegans aging and improves metabolic health, and 20HE is the primary bioactive constituent responsible for favorable effects.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
First dual AK/GSK-3 beta inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 138, 438–457.
author keywords: Antioxidant agents; Glycogen synthase kinase 3 beta (GSK-3 beta); Adenosine kinase (AK); Dual inhibitors; Molecular docking
MeSH headings : Adenosine Kinase / antagonists & inhibitors; Adenosine Kinase / metabolism; Antioxidants / chemical synthesis; Antioxidants / chemistry; Antioxidants / pharmacology; Cell Line, Tumor; Dose-Response Relationship, Drug; Glycogen Synthase Kinase 3 beta / antagonists & inhibitors; Glycogen Synthase Kinase 3 beta / metabolism; Humans; Hydrogen Peroxide / antagonists & inhibitors; Hydrogen Peroxide / pharmacology; Molecular Structure; Neuroblastoma / metabolism; Neuroblastoma / pathology; Neuroprotective Agents / chemical synthesis; Neuroprotective Agents / chemistry; Neuroprotective Agents / pharmacology; Oxidative Stress / drug effects; Protein Kinase Inhibitors / chemical synthesis; Protein Kinase Inhibitors / chemistry; Protein Kinase Inhibitors / pharmacology; Reactive Oxygen Species / metabolism; Structure-Activity Relationship
TL;DR:
The identification of compound 5l, as the first dual hAK/hGSK-3β inhibitor reported to date, holds promise for the development of new series of potential therapeutic agents for the treatment of neurodegenerative diseases characterized by an innovative pharmacological profile.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Development, and genetic and metabolic characterization of new tomato mutants with enhanced and deficient carotenoid content
JOURNAL OF HORTICULTURAL SCIENCE & BIOTECHNOLOGY, 92(5), 475–483.
author keywords: Carotenoid; lycopene; -carotene; Solanum lycopersicum; mutagenesis
TL;DR:
Genetic and metabolic analyses showed that new mutants with enhanced and deficient carotenoid content in a single genetic background of tomato cv.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 article
Vitamin A
Debelo, H., Novotny, J. A., & Ferruzzi, M. G. (2017, November). ADVANCES IN NUTRITION, Vol. 8, pp. 992–994.
MeSH headings : Humans; Nutritional Requirements; Nutritional Status; Vitamin A / blood; Vitamin A / therapeutic use; Vitamin A Deficiency / blood; Vitamin A Deficiency / complications; Vitamins / blood; Vitamins / therapeutic use
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
The effect of obesity and repeated exposure on pharmacokinetic response to grape polyphenols in humans
MOLECULAR NUTRITION & FOOD RESEARCH, 61(11).
author keywords: Bioavailability; BMI; Catechin; Epicatechin; Polyphenol; Quercetin; Resveratrol
MeSH headings : Aged; Anti-Obesity Agents / administration & dosage; Anti-Obesity Agents / blood; Anti-Obesity Agents / metabolism; Anti-Obesity Agents / therapeutic use; Area Under Curve; Body Mass Index; Dietary Supplements; Female; Fruit / chemistry; Fruit and Vegetable Juices; Humans; Kinetics; Male; Middle Aged; Obesity / blood; Obesity / diet therapy; Obesity / metabolism; Overweight / blood; Overweight / diet therapy; Overweight / metabolism; Pilot Projects; Plant Extracts / administration & dosage; Plant Extracts / metabolism; Plant Extracts / therapeutic use; Polyphenols / administration & dosage; Polyphenols / blood; Polyphenols / metabolism; Polyphenols / therapeutic use; Resveratrol; Seeds / chemistry; Stilbenes / administration & dosage; Stilbenes / blood; Stilbenes / metabolism; Stilbenes / therapeutic use; Vitis / chemistry
TL;DR:
Results suggest that that obesity and repeated exposure may modify polyphenol absorption and/or metabolism in humans.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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