Works Published in 2019

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Displaying works 41 - 60 of 99 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2019 article

Blueberries Topical Application Prevents Ozone Induced Cutaneous Inflammasome Activation

Pambianchi, E., Francesca, F., Pecorelli, A., Woodby, B., Lila, M., & Valacchi, G. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S148–S148.

By: E. Pambianchi, F. Francesca, A. Pecorelli, B. Woodby, M. Lila & G. Valacchi

Sources: Web Of Science, ORCID
Added: December 2, 2019

2019 journal article

Contribution of Berry Polyphenols to the Human Metabolome

Molecules.

By: P. Chandra n, A. Rathore n, K. Kay*, J. Everhart n, P. Curtis*, B. Burton-Freeman*, A. Cassidy*, C. Kay n

author keywords: mass spectrometry; metabolome; metabolomics; microbiome; (poly)phenol
MeSH headings : Anthocyanins / chemistry; Anthocyanins / pharmacokinetics; Blueberry Plants / chemistry; Fragaria / chemistry; Fruit / chemistry; Humans; Metabolome; Polyphenols / chemistry; Polyphenols / pharmacokinetics
TL;DR: Berry consumption in general appears to cause a fluctuation in the pools of small molecule metabolites already present at baseline, rather than the appearance of unique berry-derived metabolites, which likely reflects the ubiquitous nature of (poly)phenols in the background diet. (via Semantic Scholar)
Source: ORCID
Added: November 25, 2019

2019 journal article

Efficient stabilisation of curcumin microencapsulated into yeast cells via osmoporation

Applied Microbiology and Biotechnology, 103(23-24), 9659–9672.

author keywords: Curcumin; Osmoporation; S; cerevisiae; Antioxidant activity; Stability; Microencapsulation
MeSH headings : Cell Membrane Permeability; Curcumin / chemistry; Ethanol; Industrial Microbiology / methods; Osmotic Pressure; Saccharomyces cerevisiae / metabolism
TL;DR: Results showed that encapsulation efficiency was favoured by the increase of cells/curcumin ratio and ethanol concentration up to 60%. (via Semantic Scholar)
Source: ORCID
Added: November 12, 2019

2019 journal article

Estimation of Ascorbic Acid in Intact Acerola (<i>Malpighia emarginata</i> DC) Fruit by NIRS and Chemometric Analysis

Horticulturae.

By: F. Moraes*, R. Costa*, C. Morais*, F. Macêdo*, T. Fernandes*, R. Hoskin*, K. Lima*

author keywords: Acerola; NIRS; PLS; iPLS; GA-PLS; ascorbic acid
TL;DR: A non-destructive, reliable, and fast method to measure the ascorbic acid content in intact acerola, using near-infrared spectroscopy (NIRS) associated with multivariate calibration methods and chemometrics. (via Semantic Scholar)
Source: ORCID
Added: November 12, 2019

2019 journal article

Changes due to high oxygen and high carbon dioxide atmospheres on the general quality and the polyphenolic profile of strawberries

Postharvest Biology and Technology, 148, 49–57.

By: F. Van de Velde*, M. Méndez-Galarraga*, M. Grace n, C. Fenoglio*, M. Lila n & M. Pirovani*

Contributors: F. Velde*, M. Méndez-Galarraga*, M. Grace n, C. Fenoglio*, M. Lila n & M. Pirovani*

author keywords: Modified atmosphere packaging; Abiotic stress; Anthocyanins; Phenolic acids; Ellagitannins; Vitamin C
Sources: Crossref, ORCID
Added: November 12, 2019

2019 journal article

Banana flour phenolics inhibit trans-epithelial glucose transport from wheat cakes in a coupled in vitro digestion/Caco-2 cell intestinal model

FOOD & FUNCTION, 10(10), 6300–6311.

By: J. Pico*, S. Corbin n, M. Ferruzzi n & M. Martinez*

MeSH headings : Caco-2 Cells; Digestion; Flour / analysis; Glucose / metabolism; Humans; Intestinal Mucosa / metabolism; Musa / chemistry; Musa / metabolism; Phenols / metabolism; Triticum / chemistry; Triticum / metabolism
TL;DR: Results suggested that the amounts of quercetin and myricetin, even in traces, were critical determinants of glucose transport inhibition, which may contribute to the ability of flavonoid-rich food to regulate glucose homeostasis of meals rich in available carbohydrates. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: November 4, 2019

2019 journal article

Comparison of berry juice concentrates and pomaces and alternative plant proteins to produce spray dried protein–polyphenol food ingredients

Food & Function, 10(10), 6286–6299.

By: R. Hoskin n, J. Xiong n & M. Lila n

Contributors: R. Hoskin n, J. Xiong n & M. Lila n

MeSH headings : Animals; Blueberry Plants / chemistry; Color; Fagopyrum / chemistry; Flour / analysis; Food Handling; Food Ingredients / analysis; Fruit / chemistry; Fruit and Vegetable Juices / analysis; Peas / chemistry; Plant Extracts / chemistry; Plant Extracts / isolation & purification; Plant Proteins / chemistry; Plant Proteins / isolation & purification; Polyphenols / chemistry; Polyphenols / isolation & purification; Vaccinium macrocarpon / chemistry; Vitis / chemistry; Waste Products / analysis
TL;DR: The results suggest an efficient plant-based approach to produce value-added protein-polyphenol aggregates with broad utility as healthy food ingredients as well as good spray drying yield. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, Crossref
Added: November 4, 2019

2019 article

Carrot Molecular Genetics and Mapping

CARROT GENOME, pp. 101–117.

TL;DR: Combined, these tools will advance the breeding process for carrot by enabling a targeted approach to improving traits by utilizing marker-assisted selection (MAS) strategies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science; OpenAlex)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: October 28, 2019

2019 article

Carrot Genetics, Omics and Breeding Toolboxes

CARROT GENOME, pp. 225–245.

TL;DR: This chapter summarizes the available omics, genetics and breeding resources for carrot and other Daucus species in different public and private databases and discusses the challenges for collecting, integrating and interpreting this data with a focus on the lack of dedicated, centralized and user-friendly bioinformatics platforms, breeding toolboxes and infrastructures for the carrot genome. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: October 28, 2019

2019 article

Carrot Anthocyanin Diversity, Genetics, and Genomics

CARROT GENOME, pp. 261–277.

TL;DR: Recent advances in high-throughput sequencing and bioinformatic analyses have facilitated the discovery of candidate regulatory genes for root and petiole pigmentation associated with the P3 region in chromosome 3, as well as structural genes involved in anthocyanin glycosylation and acylation. (via Semantic Scholar)
Source: Web Of Science
Added: October 28, 2019

2019 journal article

Alaskan Berry Extracts Promote Dermal Wound Repair Through Modulation of Bioenergetics and Integrin Signaling

FRONTIERS IN PHARMACOLOGY, 10(SEP).

By: D. Esposito n, J. Overall n, M. Grace n, S. Komarnytsky n & M. Lila n

Contributors: D. Esposito n, J. Overall n, M. Grace n, S. Komarnytsky n & M. Lila n

author keywords: skin regeneration; wound healing; Alaskan berries; integrins; proanthocyanidins; epicatechins
TL;DR: Targeting cellular bioenergetics and integrin-mediated cell–ECM signaling with bioactives from Alaskan wild berries shows considerable therapeutic promise to treat chronic skin wounds and inflammatory skin disorders, as well as more generally to support regenerative healing responses and restore function in a variety of tissue and organ settings after injury or aging. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID
Added: October 14, 2019

2019 review

Ozonated Oils and Cutaneous Wound Healing

[Review of ]. CURRENT PHARMACEUTICAL DESIGN, 25(20), 2264–2278.

By: Y. Lim*, H. Lee*, B. Woodby n & G. Valacchi*

author keywords: Cutaneous wound healing; ROS; peroxidation; topical application; ozonated oil; inflammation
MeSH headings : Humans; Ozone; Phytotherapy; Plant Oils / therapeutic use; Skin; Wound Healing
TL;DR: The present review intends to summarize the actual state of the art of the topical usage of ozonated oil in cutaneous wounds with special emphasis to the importance of theozonated degree of the oil. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: October 7, 2019

2019 journal article

Suppression of Stromal Interferon Signaling by Human Papillomavirus 16

JOURNAL OF VIROLOGY, 93(19).

author keywords: E5; fibroblast; immunity; interferon; keratinocyte differentiation; organotypic culture; papillomavirus; stroma
MeSH headings : Cells, Cultured; Fibroblasts / immunology; Fibroblasts / virology; Gene Expression Profiling; Host-Pathogen Interactions; Human papillomavirus 16 / growth & development; Human papillomavirus 16 / immunology; Humans; Immune Evasion; Immunity, Innate; Immunologic Factors / antagonists & inhibitors; Interferons / antagonists & inhibitors; Keratinocytes / immunology; Keratinocytes / virology; Models, Biological; Papillomavirus Infections / immunology; Papillomavirus Infections / virology; Signal Transduction
TL;DR: HPVs infect squamous epithelia and cause several important cancers, and the role of epithelial-stromal interactions in the HPV16 life cycle is examined, showing that HPV can suppress the expression of immune-related genes in neighboring fibroblasts in a three-dimensional (3D) model of human epithelium and revealing a new role for E5 as a stromal innate immune suppressor. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: October 7, 2019

2019 journal article

Variation in anthocyanin profiles of 27 genotypes of red cabbage over two growing seasons

FOOD CHEMISTRY, 301.

By: R. Strauch n, M. Mengist n, K. Pan n, G. Yousef n, M. Iorizzo n, A. Brown n, M. Lila n

author keywords: Red cabbage; Acylated anthocyanin; Breeding population; HPLC-DAD-MSE
MeSH headings : Acylation; Anthocyanins / analysis; Anthocyanins / chemistry; Brassica / chemistry; Brassica / genetics; Brassica / metabolism; Chromatography, High Pressure Liquid; Genotype; Mass Spectrometry; Plant Breeding; Polymorphism, Genetic; Seasons
TL;DR: PCA analysis identified anthocyanin accumulation traits and genotypes with high diversity which can be utilized in future investigations into the genetic and molecular basis for anthochenin production, acylation, and diversity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: September 23, 2019

2019 journal article

Lipid nanostructures for antioxidant delivery: a comparative preformulation study

BEILSTEIN JOURNAL OF NANOTECHNOLOGY, 10, 1789–1801.

author keywords: alpha-tocopherol; cryogenic transmission electron microscopy (cryo-TEM); dermocosmetics; HO-1; nanostructured lipid carriers (NLCs); retinoic acid; skin pollution; solid lipid nanoparticles (SLNs)
TL;DR: Interestingly, it was found that pretreatment with the nanoformulation resulted in significantly reduced heme oxygenase upregulation as compared to control samples, suggesting a protective effect provided by the nanoparticles. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: September 16, 2019

2019 journal article

Extraction, Purification, and Biological Activities of Polysaccharides from Branches and Leaves of Taxus cuspidata S. et Z.

Molecules, 24(16), 2926.

author keywords: Taxus cuspidata branches and leaves; polysaccharides; extraction and purification; bioactivity
MeSH headings : Antineoplastic Agents, Phytogenic / chemistry; Antineoplastic Agents, Phytogenic / isolation & purification; Antineoplastic Agents, Phytogenic / pharmacology; Chemical Fractionation / methods; Dose-Response Relationship, Drug; Humans; Monosaccharides / chemistry; Plant Extracts / chemistry; Plant Extracts / isolation & purification; Plant Extracts / pharmacology; Plant Leaves / chemistry; Polysaccharides / chemistry; Polysaccharides / isolation & purification; Polysaccharides / pharmacology; Spectrum Analysis; Taxus / chemistry; Ultrasonic Waves
TL;DR: Pe4 polysaccharide from TCBL is a beneficial source of potential inhibitors of type II diabetes and human cervical cancer activity and the optimum extraction technology of TCBL was determined using a low-temperature and high-efficiency enzyme and ultrasound-assisted coupled extraction method. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: September 16, 2019

2019 journal article

The catalytic core of DEMETER guides active DNA demethylation in Arabidopsis

Proceedings of the National Academy of Sciences, 116(35), 17563–17571.

By: C. Zhang n, Y. Hung n, H. Rim*, D. Zhang*, J. Frost*, H. Shin*, H. Jang*, F. Liu n ...

author keywords: gene imprinting; active DNA demethylation; endosperm development; epigenetic reprogramming; Arabidopsis thaliana
MeSH headings : Arabidopsis / classification; Arabidopsis / genetics; Arabidopsis / metabolism; Arabidopsis Proteins / chemistry; Arabidopsis Proteins / metabolism; Catalytic Domain; DNA Demethylation; Epigenesis, Genetic; Evolution, Molecular; Gene Expression Regulation, Plant; Heterochromatin / genetics; Heterochromatin / metabolism; Models, Molecular; N-Glycosyl Hydrolases / chemistry; N-Glycosyl Hydrolases / metabolism; Protein Binding; Protein Interaction Domains and Motifs; Trans-Activators / chemistry; Trans-Activators / metabolism
TL;DR: A bipartite model for DME protein action is proposed and it is suggested that the DME N terminus was acquired late during land plant evolution to improve specificity and facilitate demethylation at heterochromatin targets. (via Semantic Scholar)
Sources: ORCID, Crossref
Added: September 13, 2019

2019 journal article

Acute Freeze-Dried Mango Consumption With a High-Fat Meal has Minimal Effects on Postprandial Metabolism, Inflammation and Antioxidant Enzymes

NUTRITION AND METABOLIC INSIGHTS, 12.

By: C. O'Hara*, B. Ojo*, S. Emerson*, A. Simenson*, S. Peterson*, P. Perkins-Veazie n, M. Payton*, J. Hermann*, B. Smith*, E. Lucas*

author keywords: Mango; postprandial; glucose; inflammation; antioxidant enzymes
TL;DR: When added to an HFM, acute mango consumption had modest beneficial effects on postprandial glucose and HDL-C responses, but did not alter triglyceride, inflammatory, or antioxidant enzymes. (via Semantic Scholar)
Source: Web Of Science
Added: September 9, 2019

2019 journal article

Multiple mechanisms of Rottlerin toxicity in A375 melanoma cells

BIOFACTORS, 45(6), 920–929.

By: F. Ietta*, G. Valacchi*, L. Benincasa*, A. Pecorelli*, L. Cresti* & E. Maioli*

author keywords: apoptosis; ER stress; melanoma; mitochondria; protein synthesis; rottlerin
TL;DR: In this cell line, rottlerin exhibits its main and newest cytotoxic properties, that is, growth arrest, apoptosis induction, and translation shutoff, and the drug markedly inhibited cell proliferation through cyclin D1 downregulation and induced apoptotic cell death as early as after 18 h treatment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 26, 2019

2019 journal article

Peanut protein-polyphenol aggregate complexation suppresses allergic sensitization to peanut by reducing peanut-specific IgE in C3H/HeJ mice

FOOD CHEMISTRY, 299.

By: R. Bansode*, P. Randolph*, N. Plundrich n, M. Lila n & L. Williams*

author keywords: Peanut allergy; IgE; CD63; Polyphenol; Blueberry; Cranberry
MeSH headings : Animals; Arachis / chemistry; Arachis / immunology; Female; Immunoglobulin E / immunology; Mice; Mice, Inbred C3H; Peanut Hypersensitivity / prevention & control; Plant Proteins / chemistry; Plant Proteins / immunology; Polyphenols / chemistry; Species Specificity
TL;DR: It is demonstrated for the first time that complexation of polyphenols to peanut flour can potentially lower plasma IgE of peanut-sensitized C3H/HeJ mice. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 12, 2019

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