Works Published in 2021

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Displaying works 41 - 60 of 100 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2021 journal article

A Catalog of Natural Products Occurring in Watermelon-Citrullus lanatus

FRONTIERS IN NUTRITION, 8.

author keywords: food chemistry; natural products; natural compounds; watermelon; phytochemicals
TL;DR: Knowing precisely what is in what the authors eat, as this catalog does for watermelon, supports both the rationale for certain controlled feeding studies in the field of precision nutrition, and plant breeding efforts for the development of new varieties with enhanced concentrations of specific phytochemicals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: October 18, 2021

2021 journal article

Prebiotic Inulin Supplementation and Peripheral Insulin Sensitivity in adults at Elevated Risk for Type 2 Diabetes: A Pilot Randomized Controlled Trial

NUTRIENTS, 13(9).

By: C. Mitchell*, B. Davy*, M. Ponder*, R. McMillan*, M. Hughes*, M. Hulver*, A. Neilson n, K. Davy*

author keywords: dietary fiber; prebiotics; inulin; diabetes; metabolism; gut microbiota
MeSH headings : Diabetes Mellitus, Type 2 / prevention & control; Dietary Supplements; Female; Humans; Insulin / blood; Insulin Resistance; Inulin / administration & dosage; Inulin / pharmacology; Male; Middle Aged; Pilot Projects; Prebiotics
TL;DR: Despite increases in gut Bifidobacteria, inulin supplementation did not improve peripheral insulin sensitivity, and these findings question the need for larger investigations of inulin and insulin sensitivity in this population. (via Semantic Scholar)
Source: Web Of Science
Added: October 12, 2021

2021 journal article

Fasting and postprandial trimethylamine N-oxide in sedentary and endurance-trained males following a short-term high-fat diet

PHYSIOLOGICAL REPORTS, 9(16).

By: C. Steele*, M. Baugh*, L. Griffin n, A. Neilson n, B. Davy*, M. Hulver*, K. Davy*

author keywords: endurance-trained; high-fat diet; sedentary; trimethylamine N-oxide
MeSH headings : Adolescent; Adult; Cardiometabolic Risk Factors; Diet, High-Fat / adverse effects; Dietary Fats / metabolism; Endurance Training; Fasting / metabolism; Humans; Male; Methylamines / blood; Postprandial Period; Sedentary Behavior
TL;DR: Plasma TMAO and TMA‐moiety concentrations were measured using isocratic ultraperformance liquid chromatography‐tandem mass spectrometry and VO2max was significantly higher in the endurance‐trained compared with sedentary males, and future studies are needed to identify the effects of endurance training on T MAO production. (via Semantic Scholar)
Source: Web Of Science
Added: September 7, 2021

2021 journal article

"Plurethosome" as Vesicular System for Cutaneous Administration of Mangiferin: Formulative Study and 3D Skin Tissue Evaluation

PHARMACEUTICS, 13(8).

By: M. Sguizzato*, F. Ferrara*, P. Mariani*, A. Pepe*, R. Cortesi*, N. Huang*, F. Simeliere*, P. Boldrini* ...

author keywords: phosphatidylcholine; poloxamer; mangiferin; in vitro diffusion; antioxidant
TL;DR: The antioxidant and anti-inflammatory potential effect of mangiferin against pollutants was evaluated on 3D human skin models exposed to O3 and the protective effect exerted by plurethosomes and transethosomes suggests their possible application to enhance the cutaneous antioxidant defense status. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: September 7, 2021

2021 journal article

Co-extruded wheat/okra composite blends result in soft, cohesive and resilient crumbs rich in health-promoting compounds

FOOD CHEMISTRY, 364.

author keywords: Okra; Phenolics; Dietary fiber; Extrusion; Wheat bread; Flavonols; Baking; Food structuring
MeSH headings : Abelmoschus; Bread; Flour; Hardness; Triticum
TL;DR: This work investigates the partial solubilization of cell wall polysaccharides in okra flours and the changes in the profile of free and bound phenolics through twin-screw extrusion. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Source: Web Of Science
Added: August 30, 2021

2021 article

Epigenetic remodeling by DNA glycosylases during rice reproduction

Li, M., Cui, Q., Zhang, X.-Q., & Hsieh, T.-F. (2021, September 6). MOLECULAR PLANT, Vol. 14, pp. 1433–1435.

By: M. Li n, Q. Cui n, X. Zhang* & T. Hsieh n

MeSH headings : Arabidopsis / enzymology; Arabidopsis / genetics; DNA Glycosylases / genetics; DNA Glycosylases / metabolism; DNA Methylation / physiology; DNA, Plant / genetics; DNA, Plant / metabolism; Epigenesis, Genetic; Oryza / enzymology; Oryza / genetics; Plant Development / physiology; Plant Proteins / genetics; Plant Proteins / metabolism
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science
Added: August 24, 2021

2021 journal article

High-density linkage map construction and identification of loci regulating fruit quality traits in blueberry

HORTICULTURE RESEARCH, 8(1).

By: M. Mengist n, H. Bostan n, E. Young n, K. Kay*, N. Gillitt*, J. Ballington n, C. Kay n, M. Ferruzzi n ...

TL;DR: The genetic basis of fruit quality traits in blueberry was dissected and an association between these fruit quality trait and metabolites detected by Proton nuclear magnetic resonance analysis was established. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID
Added: August 23, 2021

2021 journal article

Strawberry Consumption, Cardiometabolic Risk Factors, and Vascular Function: A Randomized Controlled Trial in Adults with Moderate Hypercholesterolemia

JOURNAL OF NUTRITION, 151(6), 1517–1526.

author keywords: strawberry; hypercholesterolemia; cardiovascular risk factors; flow-mediated dilation; (poly)phenolic metabolites
MeSH headings : Adult; Blood Pressure; Cardiometabolic Risk Factors; Cardiovascular Diseases / prevention & control; Cholesterol, LDL; Cross-Over Studies; Dietary Supplements; Female; Fragaria; Fruit; Humans; Hypercholesterolemia; Male; Middle Aged; Powders
TL;DR: Data support inclusion of strawberries in a heart-healthy diet in adults with moderate hypercholesterolemia and suggest the effect may be related to changes in microbial-derived phenolic metabolites after strawberry consumption influencing endothelial function. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 2, 2021

2021 journal article

High-Density Linkage Map Construction and QTL Identification in a Diploid Blueberry Mapping Population

FRONTIERS IN PLANT SCIENCE, 12.

By: X. Qi*, E. Ogden*, H. Bostan n, D. Sargent*, J. Ward*, J. Gilbert*, M. Iorizzo n, L. Rowland*

author keywords: Vaccinium; genetic map; fruit quality; plant development; chilling requirement; cold hardiness
TL;DR: The first high density bin map of a diploid blueberry mapping population is reported and several horticulturally important QTLs are identified for chilling requirement, cold hardiness, and fruit quality traits of color, scar size, and firmness. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: July 19, 2021

2021 journal article

Gut Microbiome-Derived Metabolite Trimethylamine N-Oxide Induces Aortic Stiffening and Increases Systolic Blood Pressure With Aging in Mice and Humans

HYPERTENSION, 78(2), 499–511.

By: V. Brunt*, A. Casso*, R. Gioscia-Ryan*, Z. Sapinsley*, B. Ziemba*, Z. Clayton*, A. Bazzoni*, N. VanDongen* ...

author keywords: advanced glycation end products; arterial stiffness; gut microbiota; pulse wave velocity
MeSH headings : Adolescent; Adult; Age Factors; Aged; Aging / blood; Animals; Aorta / drug effects; Aorta / physiology; Blood Pressure / drug effects; Blood Pressure / physiology; Female; Humans; Male; Methylamines / administration & dosage; Methylamines / blood; Mice; Middle Aged; Pulse Wave Analysis; Vascular Stiffness / drug effects; Vascular Stiffness / physiology; Young Adult
TL;DR: Ex vivo incubation of aortic rings with TMAO increased intrinsic stiffness, which was attenuated by the advanced glycation end-products crosslink breaker alagebrium and prevented by inhibition of superoxide signaling, which together increase intrinsic wall stiffness. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: July 19, 2021

2021 review

Altered Bone Status in Rett Syndrome

[Review of ]. LIFE-BASEL, 11(6).

author keywords: MeCP2; bone mineral density; bone metabolism; osteoblast; WNT pathway
TL;DR: Evidence from human and animal studies supports the idea that MECP2 mutation could be associated with altered epigenetic regulation of bone-related factors and signaling pathways, including SFRP4/WNT/β-catenin axis and RANKL/RANK/OPG system. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID
Added: July 12, 2021

2021 journal article

Modulation of Brain-Derived Neurotrophic Factor (BDNF) Signaling Pathway by Culinary Sage (Salvia officinalis L.)

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(14).

By: N. Chiang*, S. Ray*, J. Lomax n, S. Goertzen n, S. Komarnytsky n, C. Ho*, J. Munafo*

author keywords: culinary sage; cognition and memory function; brain-derived neurotrophic factor (BDNF); sage extract; benzyl 6-O-beta-D-apiofuranosyl-beta-D-glucoside (B6AG)
MeSH headings : Animals; Brain-Derived Neurotrophic Factor / genetics; Brain-Derived Neurotrophic Factor / metabolism; Cell Line, Tumor; Chromatography, High Pressure Liquid; Gene Expression Regulation, Neoplastic / drug effects; Gene Expression Regulation, Neoplastic / genetics; Glioma / genetics; Glioma / metabolism; Mass Spectrometry; Plant Leaves / chemistry; Rats; Salvia officinalis / chemistry; Signal Transduction / drug effects; Signal Transduction / genetics
TL;DR: This study provided a foundation for future investigations, including quantitative inquiries on the distribution of B6AG within the different plant organs, explorations in optimizing post-harvest practices, and aid in the development of sage varieties with elevated levels of B 6AG. (via Semantic Scholar)
Sources: ORCID, Web Of Science
Added: July 10, 2021

2021 journal article

Caryocar brasiliense Camb. fruits from the Brazilian Cerrado as a rich source of carotenoids with pro-vitamin A activity

JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 101.

By: K. Geocze*, L. Barbosa*, C. Lima*, M. Ferruzzi n, P. Fidencio*, H. Sant'ana*, F. Silverio*

author keywords: Pequi; Cerrado fruits; Carotenoids; beta-carotene; Pro-vitamin A carotenoids; Principal Components Analysis
TL;DR: The vitamin A value expressed as μg Retinol Activity Equivalent (RAE) in the fresh fruit and carotenoid profile were determined by high-performance liquid chromatography coupled to a diode array detector (HPLC- DAD), and the mainCarotenoids found were β-cryptoxanthin and β-carotene. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: July 6, 2021

2021 review

The Promising Effects of Astaxanthin on Lung Diseases

[Review of ]. ADVANCES IN NUTRITION, 12(3), 850–864.

By: J. Cheng n & A. Eroglu n

author keywords: astaxanthin; lung diseases; oxidative stress; molecular mechanism; lung cancer
MeSH headings : Humans; Lung Diseases / drug therapy; Oxidative Stress; Phosphatidylinositol 3-Kinases / metabolism; Signal Transduction; Xanthophylls / pharmacology
TL;DR: The potential role of ASX in protecting against lung diseases, including lung cancer, is reviewed and the underlying molecular mechanisms by which ASX protects against pulmonary diseases are summarized. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: July 6, 2021

2021 journal article

Inflammasome Activation in Pollution-Induced Skin Conditions

PLASTIC AND RECONSTRUCTIVE SURGERY, 147(1S-2), 15S–24S.

MeSH headings : Air Pollutants / adverse effects; Air Pollution / adverse effects; Animals; Dermatitis / immunology; Dermatitis / pathology; Dermatitis / prevention & control; Disease Models, Animal; Environmental Exposure / adverse effects; Furans; Heterocyclic Compounds, 4 or More Rings / pharmacology; Heterocyclic Compounds, 4 or More Rings / therapeutic use; Humans; Indenes; Inflammasomes / antagonists & inhibitors; Inflammasomes / immunology; Inflammasomes / metabolism; Interleukin-18 / metabolism; Interleukin-1beta / metabolism; Mice; NLR Family, Pyrin Domain-Containing 3 Protein / antagonists & inhibitors; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Nitriles / pharmacology; Nitriles / therapeutic use; Skin / drug effects; Skin / immunology; Skin / pathology; Skin Aging / immunology; Sulfonamides; Sulfones / pharmacology; Sulfones / therapeutic use
TL;DR: The cutaneous inflammasome is proposed as a novel target of pollutant exposure and the eventual usage of inflamMASome inhibitor as new technologies to counteract pollution-induced skin damage. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: July 6, 2021

2021 journal article

Formulative Study and Intracellular Fate Evaluation of Ethosomes and Transethosomes for Vitamin D3 Delivery

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(10).

author keywords: cell culture; cholecalciferol; cryogenic transmission electron microscopy; in vitro test; light microscopy; lipid nanocarriers; transmission electron microscopy
MeSH headings : Cell Line; Chemistry, Pharmaceutical / methods; Cholecalciferol / administration & dosage; Cholecalciferol / metabolism; Cholecalciferol / pharmacology; Drug Carriers / chemistry; Drug Delivery Systems / methods; Fibroblasts / drug effects; Humans; Keratinocytes / drug effects; Lipids / chemistry; Liposomes / chemistry; Myoblasts / drug effects; Nanocapsules / chemistry; Pilot Projects; Skin / metabolism; Skin Absorption; Surface-Active Agents / metabolism
TL;DR: Both ethosomes and transethosomes proven to have physicochemical properties optimal for transdermal penetration and efficient vitamin D3 loading; moreover, nanocarriers were easily internalized by all cell types, although they followed distinct intracellular fates. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: June 28, 2021

2021 journal article

Novel Spray Dried Algae-Rosemary Particles Attenuate Pollution-Induced Skin Damage

MOLECULES, 26(13).

author keywords: cosmeceuticals; pollution; phytochemicals; herbs
MeSH headings : Antioxidants / chemistry; Antioxidants / pharmacology; Cells, Cultured; Chlorella / chemistry; Cinnamates / chemistry; Depsides / chemistry; Environmental Exposure / adverse effects; Filaggrin Proteins; Humans; Rosmarinus / chemistry; Skin / injuries; Skin / metabolism; Skin / pathology; Skin Aging / drug effects
TL;DR: The ex-vivo data clearly demonstrated the ability of RSP gel to prevent an oxinflammatory phenomenon in cutaneous tissue by decreasing the levels of 4-hydroxynonenal protein adducts and active matrix metalloproteinase-9 (MMP-9) by limiting the loss of filaggrin induced by DEE exposure. (via Semantic Scholar)
Sources: ORCID, Web Of Science
Added: June 23, 2021

2021 article

Influence of simulated food and oral processing on carotenoid and chlorophyll in vitro bioaccessibility among six spinach genotypes

Hayes, M., Corbin, S., Nunn, C., Pottorff, M., Kay, C. D., Lila, M. A., … Ferruzzi, M. G. (2021, May 14). FOOD & FUNCTION, Vol. 5.

By: M. Hayes n, S. Corbin*, C. Nunn*, M. Pottorff*, C. Kay n, M. Lila n, M. Iorrizo n, M. Ferruzzi n

MeSH headings : Biological Availability; Carotenoids / chemistry; Carotenoids / metabolism; Carotenoids / pharmacokinetics; Chlorophyll / chemistry; Chlorophyll / metabolism; Chlorophyll / pharmacokinetics; Digestion; Genotype; Models, Biological; Spinacia oleracea / chemistry; Spinacia oleracea / genetics
TL;DR: It is suggested that the genotype, processing treatment, and genotype × processing (G × P) interaction may affect carotenoid and chlorophyll bioaccessibility in spinach and that food processing remains a dominant factor in modulating the bioavailability of these phytochemicals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: ORCID, Web Of Science
Added: June 22, 2021

2021 journal article

Cultivating a Three-dimensional Reconstructed Human Epidermis at a Large Scale

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 5(171).

MeSH headings : Cell Differentiation; Cells, Cultured; Coculture Techniques; Epidermal Cells; Epidermis; Filaggrin Proteins; Humans; Keratinocytes; Skin
TL;DR: This protocol represents a straightforward and reproducible in vitro method to cultivate reconstructed human epidermis as a tool to assess environmental effects and a broad range of skin-related studies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, ORCID
Added: June 21, 2021

2021 journal article

In Situ Biomanufacturing of Small Molecules in the Mammalian Gut by Probiotic Saccharomyces boulardii

ACS SYNTHETIC BIOLOGY, 10(5), 1039–1052.

author keywords: Saccharomyces boulardii; probiotic engineering; metabolic engineering; colonization profile; in situ production; beta-carotene
MeSH headings : Animals; Antineoplastic Agents / metabolism; CRISPR-Cas Systems; Feces / chemistry; Female; Gastrointestinal Microbiome; Gastrointestinal Tract / metabolism; Gastrointestinal Tract / microbiology; Gene Editing / methods; Gene Expression; Indoles / metabolism; Male; Metabolic Engineering / methods; Mice; Mice, Inbred C57BL; Microorganisms, Genetically-Modified; Multigene Family; Plasmids / genetics; Probiotics / metabolism; Promoter Regions, Genetic; Provitamins / biosynthesis; Saccharomyces boulardii / genetics; Saccharomyces boulardii / metabolism; Saccharomyces cerevisiae / genetics; beta Carotene / biosynthesis
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: June 21, 2021

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