Works Published in 2021

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Displaying works 61 - 80 of 100 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2021 journal article

Whey and soy proteins as wall materials for spray drying rosemary: Effects on polyphenol composition, antioxidant activity, bioaccessibility after in vitro gastrointestinal digestion and stability during storage

LWT-FOOD SCIENCE AND TECHNOLOGY, 149.

By: M. Grace n, R. Hoskin n, J. Xiong n & M. Lila n

author keywords: Protein-polyphenol; Phenolic diterpenes; Bioaccessibility; Rosemary antioxidants; Spray-drying
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: June 16, 2021

2021 article

An anchored chromosome-scale genome assembly of spinach improves annotation and reveals extensive gene rearrangements in euasterids

Hulse-Kemp, A. M., Bostan, H., Chen, S., Ashrafi, H., Stoffel, K., Sanseverino, W., … Van Deynze, A. (2021, June 10). PLANT GENOME.

By: A. Hulse-Kemp n, H. Bostan n, S. Chen*, H. Ashrafi n, K. Stoffel*, W. Sanseverino*, L. Li*, S. Cheng* ...

MeSH headings : Chromosomes; Gene Rearrangement; Peronospora; Plant Breeding; Spinacia oleracea / genetics
TL;DR: Diversity analysis of 75 lines indicate that variation in genes is ample for hypothesis‐driven, genomic‐assisted breeding enabled by this work, and Evolutionary analysis indicates that Spinacia is a paleohexaploid with a whole‐genome triplication followed by extensive gene rearrangements identified in this work. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: June 14, 2021

2021 journal article

Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents

ACS CHEMICAL NEUROSCIENCE, 12(9), 1716–1736.

author keywords: Endocannabinoid system; fatty acid amide hydrolase; enzyme inhibitors; selective inhibitors; epilepsy; temporal lobe epilepsy; seizures
MeSH headings : Amidohydrolases; Anticonvulsants / pharmacology; Endocannabinoids; Enzyme Inhibitors / pharmacology; Humans; Seizures
TL;DR: The discovery of selective anandamide catabolic enzyme fatty acid amide hydrolase (FAAH) inhibitors with promising antiepileptic efficacy are reported, starting from a further investigation of the authors' prototypical inhibitor 2a. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 10, 2021

2021 journal article

Ethosomes and Transethosomes for Mangiferin Transdermal Delivery

ANTIOXIDANTS, 10(5).

author keywords: ethosomes; transethosomes; mangiferin; franz cell; antioxidants
TL;DR: The effectiveness of mangiferin loaded in nanosystems to protect cells from damage was demonstrated, evaluating, in vitro, the antioxidant and anti-inflammatory effect of ethosomes and transethosomes on human keratinocytes exposed to cigarette smoke as an oxidative and inflammatory challenger. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 10, 2021

2021 journal article

Measuring consumer acceptance of instant fortified millet products using affective tests and auctions in Dakar, Senegal

INTERNATIONAL FOOD AND AGRIBUSINESS MANAGEMENT REVIEW, 24(3), 499–522.

By: H. De Groote*, B. Munyua*, D. Traore*, J. Taylor*, M. Ferruzzi n, C. Ndiaye*, I. Onyeoziri*, B. Hamaker*

author keywords: extrusion; consumers; instant; food-to-food fortification; willingness-to-pay
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: June 10, 2021

2021 article

The role of pulmonary ORCC and CLC-2 channels in the response to oxidative stress

Canella, R., Benedusi, M., Martini, M., Guiotto, A., Cervellati, F., & Valacchi, G. (2021, May 7). MOLECULAR & CELLULAR TOXICOLOGY, Vol. 5.

author keywords: Human lung epithelial cells; Chloride channels; Ozone; Oxidative stress; Patch clamp technique
TL;DR: It is suggested that O3 activates ORCC channels and slightly inhibited ClC-2 channels in the negative voltage range and opens the possibility of identifying the biomolecular changes induced by O3 allowing a possible pharmacological intervention towards chloride current due to oxidative stress. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 10, 2021

2021 journal article

Design and Nutrient Analysis of a Carotenoid-Rich Food Product to Address Vitamin A and Protein Deficiency

FOODS, 10(5).

TL;DR: The results of this project indicate that the three ingredients can be combined into a single 250 g food product to provide >300 kcal energy, complete protein, and micronutrients in a more bioavailable form. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: June 10, 2021

2021 article

BACE1 role in Alzheimer's disease and other dementias: from the theory to the practice

Cervellati, C., Valacchi, G., & Zuliani, G. (2021, December). NEURAL REGENERATION RESEARCH, Vol. 16, pp. 2407–2408.

By: C. Cervellati*, G. Valacchi* & G. Zuliani

TL;DR: Alzheimer's disease is a multifactorial and multifaceted disease, with a complex and still not completely understood pathogenesis, and it is now amply recognized that a combination of multiple biochemical, immune system and vascular abnormalities must also occur to define the direction of disease trajectory. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 10, 2021

2021 journal article

Techno-economic analysis of a grape pomace biorefinery: Production of seed oil, polyphenols, and biochar

FOOD AND BIOPRODUCTS PROCESSING, 127, 139–151.

By: Q. Jin*, . Sean F. O'Keefe*, A. Stewart*, A. Neilson n, Y. Kim* & H. Huang*

author keywords: Techno-economic analysis; Grape pomace; Seed oil; Polyphenol; Biochar
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: June 10, 2021

2021 article

Comparative phylogenomic analysis reveals evolutionary genomic changes and novel toxin families in endophytic Liberibacter pathogens

Tan, Y., Wang, C., Schneider, T., Li, H., Souza, R. F., Tang, X., … Zhang, D. (2021, June 5). (Vol. 6). Vol. 6.

Source: ORCID
Added: June 6, 2021

2021 article

Pea protein isolate characteristics modulate functional properties of pea protein-cranberry polyphenol particles

Strauch, R. C., & Lila, M. A. (2021, May 24). FOOD SCIENCE & NUTRITION, Vol. 5.

By: R. Strauch n & M. Lila n

author keywords: by-products; cranberry polyphenols; digestion; pea protein isolate; solubility
TL;DR: Plant polyphenols have a natural binding affinity for proteins, and their interaction can be exploited to form diverse aggregate particles to allow consumers to incorporate more health‐benefiting plant bioactives into their diets. (via Semantic Scholar)
Sources: ORCID, Web Of Science
Added: May 25, 2021

2021 article

Building a Resilient, Sustainable, and Healthier Food Supply Through Innovation and Technology

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 12, 2021, Vol. 12, pp. 1–28.

By: D. McClements*, R. Barrangou n, C. Hill*, J. Kokini*, M. Lila n, A. Meyer*, L. Yu*

author keywords: future foods; food production; food processing; environmental impacts; nanotechnology; gene editing; genetic engineering; artificial intelligence; robotics
MeSH headings : Agriculture; Artificial Intelligence; Biotechnology; COVID-19; Food Quality; Food Safety; Food Supply / standards; Humans; Nanotechnology; Pandemics; Robotics
TL;DR: A perspective article, written by members of the Editorial Committee of the Annual Review of Food Science and Technology, highlights some of the major challenges confronting the modern food supply chain as well as how innovations in policy and technology can be used to address them. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: May 24, 2021

2021 journal article

Extraction, Purification, and Biological Activities of Flavonoids from Branches and Leaves of Taxus cuspidata S. et Z.

BIORESOURCES, 16(2), 2655–2682.

By: P. Jiang*, Y. Zhao*, J. Xiong n, F. Wang*, L. Xiao*, S. Bao*, X. Yu*

author keywords: Taxus cuspidata; Extraction; Purification; Flavonoids; Biological activity
TL;DR: Epicatechin and catechin were potent antioxidants and active agents for inhibiting type II diabetes and all 4 compounds exerted clear antitumor activity against MCF-7, Hela, and HepG2 cells. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: May 24, 2021

2021 review

Endocannabinoid System and Its Regulation by Polyunsaturated Fatty Acids and Full Spectrum Hemp Oils

[Review of ]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(11).

By: S. Komarnytsky n, T. Rathinasabapathy n, C. Wagner n, B. Metzger*, C. Carlisle*, C. Panda*, S. Le Brun-Blashka*, J. Troup*, S. Varadharaj*

Contributors: S. Komarnytsky n, T. Rathinasabapathy n, C. Wagner n, B. Metzger*, C. Carlisle*, C. Panda*, S. Le Brun-Blashka*, J. Troup*, S. Varadharaj*

author keywords: ECS tone; phytocannabinoids; inflammation resolution; oxidative stress; systemic redox balance
MeSH headings : Adenosine / metabolism; Animals; Cannabinoids / metabolism; Cannabis / metabolism; Diet; Endocannabinoids / metabolism; Fatty Acids, Unsaturated / metabolism; Homeostasis / physiology; Humans; Inflammation / metabolism; Lipid Metabolism / physiology; Oxidative Stress / physiology; Plant Extracts / metabolism; Signal Transduction / physiology; TRPV Cation Channels / metabolism
TL;DR: Clinical evidence reviewed in this study links PUFAs and cannabinoids to changes in ECS tone, immune function, metabolic and oxidative stress adaptation, and overall maintenance of a well-balanced systemic function of the body. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: May 24, 2021

2021 journal article

Use of dietary phytochemicals for inhibition of trimethylamine N-oxide formation

JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 91.

By: L. Iglesias-Carres n, M. Hughes*, C. Steele*, M. Ponder*, K. Davy* & A. Neilson n

author keywords: Atherosclerosis; Cardiovasculardisease; Phytochemicals; TMAO
MeSH headings : Animals; Atherosclerosis / metabolism; Atherosclerosis / therapy; Cardiovascular Diseases / metabolism; Cardiovascular Diseases / therapy; Drug Discovery; Gastrointestinal Microbiome / drug effects; Humans; Lipid Metabolism / drug effects; Methylamines / antagonists & inhibitors; Methylamines / metabolism; Oxidative Stress / drug effects; Phytochemicals / pharmacology
TL;DR: The information provided by this review outlines the current state of the art of the role of phytochemicals as TMAO reducing agents, providing valuable insight to further advance in this field of study. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 26, 2021

2021 journal article

Alterations in oxygen metabolism are associated to lung toxicity triggered by silver nanoparticles exposure

FREE RADICAL BIOLOGY AND MEDICINE, 166, 324–336.

By: M. Garces*, N. Magnani*, A. Pecorelli*, V. Calabro*, T. Marchini*, L. Caceres*, E. Pambianchi*, J. Galdoporpora* ...

author keywords: Nanoparticles; Lung epithelium; Nanotoxicology; Oxidative metabolism; NADPH oxidase; Mitochondria
MeSH headings : Animals; Hydrogen Peroxide; Lung; Metal Nanoparticles / toxicity; Mice; Oxygen; Silver
TL;DR: Results show that AgNP exposure alters O2 metabolism leading to a redox imbalance, which may be responsible for the impaired lung function observed due to alveolar epithelial injury. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: April 19, 2021

2021 article

Journal of Nutritional Biochemistry Special Issue: Polyphenols, obesity, and cardiometabolic health

Bruno, R. S., Neilson, A. P., Lambert, J. D., & Moustaid-Moussa, N. (2021, March). JOURNAL OF NUTRITIONAL BIOCHEMISTRY, Vol. 89.

MeSH headings : Cardiovascular Diseases / prevention & control; Gastrointestinal Microbiome / drug effects; Humans; Obesity / prevention & control; Obesity / therapy; Polyphenols / administration & dosage; Polyphenols / metabolism; Risk Factors; Tea / chemistry
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: April 12, 2021

2021 article

Alteration of cellular defensive response and a possible involvement of ferroptosis cell death in Rett syndrome disorder

Guiotto, A., Cordone, V., Benedusi, M., Cervellati, F., Hayek, J., Cervellati, C., … Pecorelli, A. (2021, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165.

UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 5, 2021

2021 article

Mitochondrial dysfunction fuels inflammasome machinery in Autism Spectrum Disorder

Pecorelli, A., Cordone, V., Guiotto, A., Cervellati, F., Benedusi, M., Cervellati, C., … Valacchi, G. (2021, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165.

Sources: Web Of Science, NC State University Libraries
Added: April 5, 2021

2021 article

NALP1 involvement in cigarette smoke induces cutaneous inflammation

Prieux, R., Benedusi, M., Ferrara, F., Guiotto, A., Cervellati, F., & Valacchi, G. (2021, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165.

By: R. Prieux, M. Benedusi, F. Ferrara, A. Guiotto, F. Cervellati & G. Valacchi

Sources: Web Of Science, NC State University Libraries
Added: April 5, 2021

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