Works Published in 2019

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Displaying works 81 - 99 of 99 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2019 article

Immunometabolism: A Multi-Omics Approach to Interpreting the Influence of Exercise and Diet on the Immune System

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 10, Vol. 10, pp. 341–363.

By: D. Nieman*, M. Lila n & N. Gillitt*

author keywords: exercise; diet; immune function; metabolomics; lipidomics; proteomics
MeSH headings : Diet; Exercise; Humans; Immune System; Metabolism
TL;DR: Emerging evidence using large multi-omics data sets supports the combined intake of fruit sugars and phytochemicals by athletes during heavy exertion as an effective strategy to improve metabolic recovery, augment viral defense, and counter postexercise inflammation and immune dysfunction at the cell level. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: April 22, 2019

2019 journal article

Epigenetic modification of ESP, encoding a putative long noncoding RNA, affects panicle architecture in rice

Rice, 12(1).

By: X. Luan, S. Liu*, S. Ke*, H. Dai*, X. Xie*, T. Hsieh n, X. Zhang*

author keywords: Rice; lncRNA; Epigenetic; Panicle; Pseudogene
TL;DR: It is demonstrated that epigenetic modification of ESP is associated with the regulation of panicle architecture in rice, and the methylation status of 26 CGs and 13 CHGs within a continuous 313-bp region is essential for theregulation of ESP expression. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: April 22, 2019

2019 journal article

Citrulline and Arginine Content of Taxa of Cucurbitaceae

HORTICULTURAE, 5(1).

By: J. Hartman n, T. Wehner n, G. Ma n & P. Perkins-Veazie n

author keywords: Survey; Cucurbits; Citrullus lanatus; phytonutrients; Cucumis sativus; Cucumis melo; Melothria scabra; Cucumis metuliferus
TL;DR: Watermelon is the most significant, natural plant source of L-citrulline, a non-proteinaceous amino acid that benefits cardiovascular health and increases vasodilation in many tissues of the body. (via Semantic Scholar)
Source: Web Of Science
Added: April 22, 2019

2019 journal article

Improving iron and zinc bioaccessibility through food-to-food fortification of pearl millet with tropical plant foodstuffs (moringa leaf powder, roselle calyces and baobab fruit pulp)

JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE, 56(4), 2244–2256.

By: R. Merwe*, J. Kruger*, M. Ferruzzi*, K. Duodu* & J. Taylor*

author keywords: Baobab; Bioaccessibility; Fortification; Iron; Moringa; Roselle; Zinc
TL;DR: Food-to-food fortification of staple cereal foods with moringa leaves, roselle calyces or baobab fruit pulp plus a provitamin A source can potentially sustainably improve iron and zinc bioavailability in the diets of at-risk communities in the Semi-arid Tropics. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 15, 2019

2019 journal article

Bone status in relation to ambulatory performance in girls with Rett syndrome: a 10-year longitudinal study

PEDIATRIC RESEARCH, 85(5), 639–643.

By: C. Caffarelli*, V. Francolini n, J. Hayek*, G. Valacchi*, S. Giannotti*, R. Nuti*, S. Gonnelli*

MeSH headings : Absorptiometry, Photon; Adolescent; Bone Density; Bone and Bones / diagnostic imaging; Bone and Bones / physiology; Child; Child Nutrition Sciences; Child, Preschool; Cholecalciferol / administration & dosage; Disabled Persons; Female; Finger Phalanges / diagnostic imaging; Follow-Up Studies; Fractures, Bone / diagnostic imaging; Humans; Infant; Longitudinal Studies; Nutritional Status; Rett Syndrome / diagnostic imaging; Rett Syndrome / physiopathology; Surveys and Questionnaires; Ultrasonography; Vitamin D / blood; Walking
TL;DR: This longitudinal study suggests that both ambulatory and nonambulatory Rett subjects present a progressive deterioration of bone status as assessed by quantitative ultrasound parameters, and the ambulatory impairment and the nutritional status seem to play a key role in the deterioration ofBone status. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 9, 2019

2019 journal article

Conjugation of LasR Quorum-Sensing Inhibitors with Ciprofloxacin Decreases the Antibiotic Tolerance of P-aeruginosa Clinical Strains

JOURNAL OF CHEMISTRY, 2019.

By: D. Bortolotti*, C. Trapella*, A. Bragonzi*, P. Marchetti*, V. Zanirato*, A. Alogna*, V. Gentili*, C. Cervellati* ...

TL;DR: This work has identified, for the first time, a QSi conjugated with ciprofloxacin (ET37), that is able to reduce the formation of biofilm and the onset of tolerant clones in P. aeruginosaclinical strains and could have a wide application in clinical setting. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 9, 2019

2019 journal article

Starch digested product analysis by HPAEC reveals structural specificity of flavonoids in the inhibition of mammalian alpha-amylase and alpha-glucosidases

FOOD CHEMISTRY, 288, 413–421.

author keywords: Starch digestive enzymes; Inhibition; Flavonoids; HPAEC; Ring structure
MeSH headings : Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Colorimetry; Enzyme Assays; Enzyme Inhibitors / chemistry; Enzyme Inhibitors / metabolism; Flavonoids / chemistry; Flavonoids / metabolism; Kinetics; Starch / analysis; Starch / metabolism; Substrate Specificity; alpha-Amylases / antagonists & inhibitors; alpha-Amylases / metabolism; alpha-Glucosidases / chemistry; alpha-Glucosidases / metabolism
TL;DR: This study shows that direct measurement of starch digestion products by HPAEC should be used in inhibition studies, and provides insights into structure-function aspects of polyphenols in controlling starch digestion rate. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 9, 2019

2019 journal article

A substitute variety for agronomically and medicinally important Serenoa repens (saw palmetto)

SCIENTIFIC REPORTS, 9.

MeSH headings : Conservation of Natural Resources; Fruit / anatomy & histology; Fruit / chemistry; Fruit / metabolism; Humans; Lipid Metabolism; Lipids / analysis; Male; Metabolomics; Phytotherapy / methods; Plant Extracts / therapeutic use; Plants, Medicinal / anatomy & histology; Plants, Medicinal / chemistry; Plants, Medicinal / metabolism; Prostatic Hyperplasia / drug therapy; Secondary Metabolism; Serenoa / chemistry; Serenoa / metabolism; Spatial Analysis; Water / analysis; Water / metabolism
TL;DR: The first study, to propose the use of the S. repens forma glauca (silver variety) as a qualitative substitute for the wild variety, to support its conservation and provide a new strategy for studying phenotypic traits and metabolite synthesis of closely related plant varieties. (via Semantic Scholar)
Source: Web Of Science
Added: April 2, 2019

2019 journal article

Characterization and Potential Antidiabetic Activity of Proanthocyanidins from the Barks of Acacia mangium and Larix gmelinii

Journal of Chemistry, 2019, 1–9.

By: X. Chen*, J. Xiong n, Q. He* & F. Wang*

Contributors: X. Chen*, J. Xiong n, Q. He* & F. Wang*

TL;DR: The results indicate that proanthocyanidins from the barks of A. mangium and L. gmelinii have potential antidiabetic properties, and a significant relationship between carbolytic enzymes inhibition and degree of polymerization was established. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: April 2, 2019

2019 journal article

Antiglycative Activity and RAGE Expression in Rett Syndrome

CELLS, 8(2).

By: V. Cordone*, A. Pecorelli n, M. Benedusi*, S. Santini*, S. Falone*, J. Hayek*, F. Amicarelli*, G. Valacchi n

author keywords: methylglyoxal; glyoxalases; advanced glycation end products; MeCP2; dicarbonyl stress; fibroblasts
MeSH headings : Adolescent; Adult; Antigens, Neoplasm / metabolism; Cell Survival / drug effects; Child; Female; Fibroblasts / drug effects; Fibroblasts / metabolism; Glycosylation; Humans; Lactoylglutathione Lyase / metabolism; Mitogen-Activated Protein Kinases / metabolism; Pyruvaldehyde / pharmacology; Rett Syndrome / metabolism; Rett Syndrome / pathology; Thiolester Hydrolases / metabolism; Young Adult
TL;DR: Besides OxInflammation, RTT is associated with reshaping of the major defense systems against dicarbonyl stress, along with an altered cellular stress response towards pro-glycating insults. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 25, 2019

2019 journal article

Skin damage by tropospheric ozone

HAUTARZT, 70(3), 163–168.

By: K. Fuks*, B. Woodby n & G. Valacchi n

author keywords: Air pollution; Skin aging; Skin wrinkling; Oxidative stress; Peroxidation
MeSH headings : Air Pollutants / adverse effects; Air Pollution; Humans; Lipid Peroxidation / drug effects; Nitrogen Dioxide / analysis; Oxidative Stress; Ozone / adverse effects; Ozone / analysis; Particulate Matter / analysis; Public Health; Skin Aging / drug effects; Skin Aging / radiation effects; Ultraviolet Rays / adverse effects
TL;DR: The experimental evidence suggests a positive correlation of O3 exposure with oxidative damage, impaired antioxidant defence and proinflammatory response in the skin, and skin might be a potentially overlooked target organ of ambient O3. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 25, 2019

2019 journal article

Mutation in a putative glycosyltransferase-like gene causes programmed cell death and early leaf senescence in rice

Rice, 12(1).

By: S. Ke*, S. Liu*, X. Luan, X. Xie*, T. Hsieh n & X. Zhang*

author keywords: Rice; PCD; Glycosylation; Senescence; Ethylene
TL;DR: Results highlight the importance of protein O-glycosylation in PCD and leaf senescence, and suggest a possible role of OsPSL in ethylene signaling. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: March 4, 2019

2019 journal article

Maternal small RNAs mediate spatial-temporal regulation of gene expression, imprinting, and seed development in Arabidopsis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116(7), 2761–2766.

By: R. Kirkbride*, J. Lu*, C. Zhang*, R. Mosher*, D. Baulcombe* & Z. Chen*

author keywords: DNA methylation; imprinting; epigenetics; polyploidy; heterosis
MeSH headings : Arabidopsis / embryology; Arabidopsis / genetics; Arabidopsis Proteins / genetics; Gene Expression Regulation, Plant / physiology; Genomic Imprinting; Ovule; RNA, Plant / physiology; RNA, Small Interfering / genetics; Seeds / growth & development
TL;DR: It is demonstrated that spatial and temporal expression patterns of these genes in the endosperm are regulated by the NRPD1-mediated pathway irrespective of complete silencing (AGL91) or incomplete silencing(AGL40) of these target genes, and altered expression of these siRNA-targeted genes affects seed size. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: February 25, 2019

2019 journal article

Binding of peanut allergen Ara h 2 with Vaccinium fruit polyphenols

FOOD CHEMISTRY, 284, 287–295.

By: N. Plundrich n, B. Cook n, S. Maleki*, D. Fourches n & M. Lila n

author keywords: Ara h 2; Molecular docking; Polyphenol; IgE binding; Circular dichroism (CD); Food allergy
MeSH headings : 2S Albumins, Plant / chemistry; 2S Albumins, Plant / immunology; 2S Albumins, Plant / metabolism; Antigens, Plant / chemistry; Antigens, Plant / immunology; Antigens, Plant / metabolism; Arachis / metabolism; Biflavonoids / chemistry; Biflavonoids / metabolism; Binding Sites; Catechin / chemistry; Catechin / metabolism; Chlorogenic Acid / chemistry; Chlorogenic Acid / metabolism; Circular Dichroism; Epitopes / chemistry; Epitopes / metabolism; Fruit / chemistry; Fruit / metabolism; Glycoproteins / chemistry; Glycoproteins / immunology; Glycoproteins / metabolism; Humans; Immunoglobulin E / chemistry; Immunoglobulin E / metabolism; Molecular Docking Simulation; Polyphenols / chemistry; Polyphenols / metabolism; Proanthocyanidins / chemistry; Proanthocyanidins / metabolism; Protein Binding; Protein Structure, Secondary; Spectrophotometry; Vaccinium / chemistry; Vaccinium / metabolism
TL;DR: Results suggest that certain polyphenols can inhibit IgE recognition of Ara h 2 by obstructing linear IgE epitopes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: February 25, 2019

2019 journal article

Electrodialysis Extraction of Pufferfish Skin (Takifugu flavidus): A Promising Source of Collagen

MARINE DRUGS, 17(1).

By: J. Chen*, M. Li n, R. Yi*, K. Bai*, G. Wang*, R. Tan*, S. Sun*, N. Xu*

author keywords: skin collagen; electrodialysis; thermal stability; Takifugu flavidus
MeSH headings : Amino Acids / metabolism; Animals; Collagen / chemistry; Collagen / metabolism; Fish Proteins / chemistry; Fish Proteins / metabolism; Skin / chemistry; Skin / metabolism; Takifugu / metabolism; Temperature
TL;DR: All evidence suggests that electrodialysis is a promising technique for extracting collagen in the fishing industry and that T. flavidus skin collagen could serve as an alternative source of collagen to meet the increasing demand from consumers. (via Semantic Scholar)
Source: Web Of Science
Added: February 25, 2019

2019 journal article

QTLs associated with flesh quality traits in an elitexelite watermelon population

EUPHYTICA, 215(2).

By: L. Fall*, P. Perkins-Veazie n, G. Ma n & C. McGregor*

author keywords: Citrullus lanatus; Brix; Sugar; Fructose; Sucrose; Glucose; Lycopene; Citrulline; Arginine
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: February 11, 2019

2019 journal article

A Cluster of MYB Transcription Factors Regulates Anthocyanin Biosynthesis in Carrot (Daucus carota L.) Root and Petiole

FRONTIERS IN PLANT SCIENCE, 9.

author keywords: Daucus carota L.; anthocyanin accumulation; root and petiole; regulation; fine mapping; transcriptome; candidate genes
TL;DR: Fine mapping and functional evidence for the candidacy of six MYB transcription factors associated with the regulation of carrot anthocyanin biosynthesis are provided, suggesting DcMYB11 is a candidate gene for petiole pigmentation in all the purple carrot sources in this study. (via Semantic Scholar)
Source: Web Of Science
Added: January 28, 2019

2019 journal article

Blueberry polyphenol-protein food ingredients: The impact of spray drying on the in vitro antioxidant activity, anti-inflammatory markers, glucose metabolism and fibroblast migration

Food Chemistry, 280, 187–194.

By: R. Hoskin n, J. Xiong n, D. Esposito n & M. Lila n

Contributors: R. Hoskin n, J. Xiong n, D. Esposito n & M. Lila n

author keywords: Berries; By-products; Drying; Inflammation; Phytochemicals
MeSH headings : Animals; Anti-Inflammatory Agents / chemistry; Anti-Inflammatory Agents / pharmacology; Antioxidants / chemistry; Blueberry Plants / chemistry; Blueberry Plants / metabolism; Cell Line; Cell Movement / drug effects; Cell Survival / drug effects; Cyclooxygenase 2 / metabolism; Fibroblasts / cytology; Fibroblasts / drug effects; Fibroblasts / metabolism; Freeze Drying; Glucose / metabolism; Interleukin-1beta / metabolism; Macrophages / cytology; Macrophages / drug effects; Macrophages / metabolism; Mice; Plant Proteins / chemistry; Plant Proteins / pharmacology; Polyphenols / chemistry; Polyphenols / pharmacology; Protein Aggregates; RAW 264.7 Cells; Rats; Reactive Oxygen Species / metabolism
TL;DR: The data suggests that spray drying is a convenient and cost-effective technique to produce blueberry-polyphenol food ingredients with preserved phytochemicals with biological activities. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: January 28, 2019

2019 journal article

Simultaneous LC-MS quantification of anthocyanins and non-anthocyanin phenolics from blueberries with widely divergent profiles and biological activities

Food Chemistry, 277, 336–346.

By: M. Grace n, J. Xiong n, D. Esposito n, M. Ehlenfeldt* & M. Lila n

Contributors: M. Grace n, J. Xiong n, D. Esposito n, M. Ehlenfeldt* & M. Lila n

author keywords: Pink-fruited; Blueberries; LC-IT-TOF-MS; Quantification; Antioxidant; Anti-inflammatory; PCA
MeSH headings : Animals; Anthocyanins / analysis; Anthocyanins / pharmacology; Anti-Inflammatory Agents / analysis; Anti-Inflammatory Agents / pharmacology; Antioxidants / analysis; Antioxidants / pharmacology; Biological Assay; Blueberry Plants / chemistry; Cell Survival / drug effects; Chromatography, Liquid; Color; Flavonoids / analysis; Flavonoids / pharmacology; Flavonols / analysis; Flavonols / pharmacology; Fruit / chemistry; Hydroxybenzoates / analysis; Hydroxybenzoates / pharmacology; Limit of Detection; Mass Spectrometry; Mice; Nitric Oxide / metabolism; Phenols / analysis; Phenols / pharmacology; Plant Extracts / analysis; Plant Extracts / pharmacology; RAW 264.7 Cells; Reactive Oxygen Species / metabolism; Reproducibility of Results; Resveratrol / analysis; Resveratrol / pharmacology
TL;DR: A sensitive and straightforward LC-IT-TOF-MS method was validated for the profiling and simultaneous quantification of anthocyanins, flavan-3-ols, flavonols, phenolic acids, and resveratrol in blueberry genotypes with fruit color ranging from deep purple to various shades of pink. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: December 17, 2018

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