Works Published in 2014
Displaying works 21 - 40 of 125 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2014 journal article
Sulforaphane represses matrix-degrading proteases and protects cartilage from destruction in vitro and in vivo
Osteoarthritis and Cartilage, 22, S322–S323.
www.oarsijournal.com (publisher PDF)
Sources: Crossref, ORCID
Added: January 5, 2020
2014 journal article
Unraveling the potential of CRISPR-Cas9 for gene therapy
Expert Opinion on Biological Therapy, 15(3), 311–314.
author keywords: Cas9; CRISPR; gene therapy; genome editing
MeSH headings : Animals; CRISPR-Cas Systems / genetics; DNA Repair / genetics; Genetic Therapy / methods; Genetic Therapy / trends; Genome; Humans
TL;DR:
The molecular machinery from the prokaryotic clustered regularly interspaced short palindromic repeats (CRISPR)-Cas immune system has broadly been repurposed for genome editing in eukaryotes and has opened new avenues for the investigation of genetic diseases in general, and for gene therapy applications in particular.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: January 2, 2020
2014 journal article
Bacteriophage exclusion, a new defense system
The EMBO Journal, 34(2), 134–135.
MeSH headings : Bacillus subtilis / virology; Bacteriophages / genetics; Bacteriophages / pathogenicity; DNA Methylation; DNA Modification Methylases / genetics; Genome, Microbial; Virulence / genetics
TL;DR:
Bacteriophage exclusion (BREX) is unveiled as a novel, widespread bacteriophages resistance system that provides innate immunity against virulent and temperate phage in bacteria.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
10. Reduced Inequalities
(OpenAlex)
Source: ORCID
Added: January 2, 2020
2014 journal article
Short communication: Determination of Salmonella clustered regularly interspaced short palindromic repeats (CRISPR) diversity on dairy farms in Wisconsin and Minnesota
Journal of Dairy Science, 97(10), 6370–6377.
author keywords: salmonellosis; cow; clustered regularly interspaced short palindromic repeats (CRISPR)
MeSH headings : Animals; Base Sequence; Cattle; Cattle Diseases / epidemiology; Cattle Diseases / microbiology; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; Dairying; Feces / microbiology; Female; Genetic Variation; Genotype; Humans; Minnesota / epidemiology; Molecular Sequence Data; Salmonella / genetics; Salmonella / isolation & purification; Salmonella Food Poisoning / epidemiology; Salmonella Food Poisoning / microbiology; Salmonella Infections, Animal / epidemiology; Salmonella Infections, Animal / microbiology; Sequence Analysis, DNA; Serogroup; Wisconsin / epidemiology
TL;DR:
The results indicate that Salmonella strains present in smaller dairy herds (<500 head) are specific to that farm and new Salmonellosis strains may emerge over time.
(via Semantic Scholar)
Source: ORCID
Added: January 2, 2020
2014 article
Functions and Applications of RNA-Guided CRISPR-Cas Immune Systems
Barrangou, R., & Horvath, P. (2014, October). Encyclopedia of Molecular Cell Biology and Molecular Medicine.
TL;DR:
The inheritable and hypervariable nature of these loci can be used to track the phylogenetic path of an organism and reveal the evolutionary interplay between hosts and their viruses.
(via Semantic Scholar)
Source: ORCID
Added: January 2, 2020
2014 journal article
The pharmacokinetics of anthocyanins and their metabolites in humans
British Journal of Pharmacology, 171(13), 3268–3282.
Source: ORCID
Added: November 13, 2019
2014 journal article
A moderate-fat diet containing pistachios improves emerging markers of cardiometabolic syndrome in healthy adults with elevated LDL levels
British Journal of Nutrition, 112(5), 744–752.
author keywords: Pistachios; Small and dense LDL; HDL subclasses; Insulin resistance; Cardiometabolic disease; C-reactive protein; Plant sterols
MeSH headings : Anticholesteremic Agents / administration & dosage; Biomarkers / blood; C-Reactive Protein / analysis; Cardiovascular Diseases / blood; Cardiovascular Diseases / prevention & control; Cholesterol / blood; Cross-Over Studies; Dietary Fats / administration & dosage; Female; Humans; Insulin Resistance; Lipoproteins / blood; Lipoproteins, LDL / blood; Male; Metabolic Syndrome / blood; Metabolic Syndrome / prevention & control; Middle Aged; Nuts / chemistry; Phytosterols / administration & dosage; Phytotherapy; Pistacia; Sitosterols / blood; Triglycerides / blood
TL;DR:
In conclusion, the inclusion of pistachios in a moderate-fat diet favourably affects the cardiometabolic profile in individuals with an increased risk of CVD.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: November 13, 2019
2014 journal article
Methods for Isolating, Identifying, and Quantifying Anthocyanin Metabolites in Clinical Samples
Analytical Chemistry, 86(20), 10052–10058.
MeSH headings : Anthocyanins / analysis; Chromatography, High Pressure Liquid; Tandem Mass Spectrometry
TL;DR:
The described methods provide suitable versatility for the identification and quantification of an extensive series of anthocyanin metabolites for use in future clinical studies exploring absorption, distribution, metabolism, and elimination.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, ORCID
Added: November 13, 2019
2014 journal article
Structural characterisation and cell viability of a spray dried probiotic yoghurt produced with goats' milk and Bifidobacterium animalis subsp. lactis (BI-07)
International Dairy Journal.
Source: ORCID
Added: November 12, 2019
2014 journal article
Dried camu-camu (Myrciaria dubia H.B.K. McVaugh) industrial residue: A bioactive-rich Amazonian powder with functional attributes
Food Research International.
author keywords: Industrial residue; Amazonia; Drying; Flavonoids; Antimicrobial; Antienzymatic
TL;DR:
The dried camu-camu residue is presented as a natural powder with bioactive and functional properties and its physicochemical characteristics, bioactive content, in vitro antidiabetic potential and antimicrobial activities are investigated.
(via Semantic Scholar)
Source: ORCID
Added: November 12, 2019
2014 book
DNA Methods in Food Safety: Molecular Typing of Foodborne and Waterborne Bacterial Pathogens
In DNA METHODS IN FOOD SAFETY: MOLECULAR TYPING OF FOODBORNE AND WATERBORNE BACTERIAL PATHOGENS (pp. 1–392).
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Probiotic-mediated modulation of host gene expression
Interactive Probiotics, 81–98.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018
2014 journal article
Ajuga turkestanica increases Notch and Wnt signaling in aged skeletal muscle
European Review for Medical and Pharmacological Sciences, 18(17), 2584–2592.
Source: NC State University Libraries
Added: August 6, 2018
2014 journal article
Thermal principles and kinetics
Food Processing: Principles and Applications, 2nd Edition, 17–31.
Sources: NC State University Libraries, ORCID
Added: August 6, 2018
2014 journal article
The Protective Effects of a Polyphenol-Enriched Protein Powder on Exercise-Induced Susceptibility to Virus Infection
PHYTOTHERAPY RESEARCH, 28(12), 1829–1836.
author keywords: virus infection; polyphenols; green tea; blueberry extract
MeSH headings : Adult; Athletes; Dietary Supplements; Disease Susceptibility / physiopathology; Exercise; Female; HeLa Cells; Humans; Immune Tolerance / drug effects; Male; Middle Aged; Polyphenols / pharmacology; Running; Soybean Proteins; Tea; Vaccinium; Vesiculovirus; Virus Diseases / prevention & control; Young Adult
TL;DR:
It is indicated that polyphenol complexes containing blueberry and green tea have the potential to protect athletes from virus infections following rigorous exercise.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 review
Insights into glycogen metabolism in Lactobacillus acidophilus: impact on carbohydrate metabolism, stress tolerance and gut retention
[Review of ]. MICROBIAL CELL FACTORIES, 13.
author keywords: Lactobacilli; Glycogen; Probiotic; Raffinose; Gastrointestinal retention
MeSH headings : Adaptation, Physiological / drug effects; Animals; Carbohydrate Metabolism / drug effects; Carbon / pharmacology; Colony Count, Microbial; Gastrointestinal Tract / drug effects; Gastrointestinal Tract / microbiology; Glycogen / biosynthesis; Glycogen / metabolism; Humans; Lactobacillus acidophilus / drug effects; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / growth & development; Lactobacillus acidophilus / metabolism; Metabolic Networks and Pathways / drug effects; Metabolic Networks and Pathways / genetics; Mice; Models, Biological; Mutation / genetics; Operon / genetics; Prokaryotic Cells / drug effects; Prokaryotic Cells / metabolism; Raffinose / pharmacology; Species Specificity; Stress, Physiological / drug effects; Trehalose / pharmacology
TL;DR:
The present in vivo studies established the significance of glycogen biosynthesis on the competitive retention of L. acidophilus in the mouse intestinal tract, demonstrating for the first time that the ability to synthesize intracellular glycogen contributes to gut fitness and retention among probiotic microorganisms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
The evolutionary history and diagnostic utility of the CRISPR-Cas system within Salmonella enterica ssp enterica
PEERJ, 2.
author keywords: Salmonella; Horizontal gene transfer; Evolution; CRISPR; Outbreak; Phylogeny; Whole genome sequencing; Typing
TL;DR:
A novel clustering approach based onCRISPR spacer content is developed, but it is found that typing based on CRISPRs was less accurate than the MLST-based alternative; typed based on WGS data was the most accurate.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
10. Reduced Inequalities
(OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Selection, Characterization and Application of Nucleic Acid Aptamers for the Capture and Detection of Human Norovirus Strains
PLOS ONE, 9(9).
MeSH headings : Aptamers, Nucleotide / chemistry; Aptamers, Nucleotide / metabolism; Bacteriological Techniques / methods; DNA, Viral / chemistry; DNA, Viral / metabolism; Feces / virology; Food Microbiology; Humans; Lettuce / virology; Molecular Structure; Norovirus / classification; Norovirus / genetics; Norovirus / isolation & purification; Sensitivity and Specificity
TL;DR:
These ssDNA aptamer candidates show promise as broadly reactive reagents for use in HuNoV capture and detection assays in various sample types.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Concentrating Immunoprotective Phytoactive Compounds from Fruits and Vegetables into Shelf-stable Protein-rich Ingredients
PLANT FOODS FOR HUMAN NUTRITION, 69(4), 317–324.
author keywords: Muscadine; Kale; Polyphenolics; Carotenoids; Glucosinolates; Protein isolate
MeSH headings : Brassica / chemistry; Carotenoids / analysis; Diet; Dietary Proteins; Food Handling; Fruit / chemistry; Functional Food; Glucosinolates / analysis; Humans; Immunologic Factors; Plant Extracts / chemistry; Polyphenols / analysis; Vegetables / chemistry; Vitis / chemistry
TL;DR:
Neither total phenolics nor glucosinolates were significantly diminished even after long term storage at 4, 20, or 37 °C, whereas carotenoids degraded over time, particularly at higher temperatures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Bioactive Capacity, Sensory Properties, and Nutritional Analysis of a Shelf Stable Protein-rich Functional Ingredient with Concentrated Fruit and Vegetable Phytoactives
PLANT FOODS FOR HUMAN NUTRITION, 69(4), 372–378.
author keywords: Muscadine; Kale; Protein isolate; Inflammatory biomarkers
MeSH headings : Animals; Anti-Inflammatory Agents / pharmacology; Anti-Inflammatory Agents / therapeutic use; Brassica / chemistry; Cannabis; Carotenoids / pharmacology; Carotenoids / therapeutic use; Chemokine CCL2 / metabolism; Diet; Dietary Proteins / analysis; Fruit / chemistry; Functional Food / analysis; Glucosinolates / pharmacokinetics; Glucosinolates / pharmacology; Humans; Inflammation / drug therapy; Inflammation / metabolism; Interleukin-6 / metabolism; Mice; Nutritive Value; Plant Preparations / pharmacology; Plant Preparations / therapeutic use; Polyphenols / pharmacology; Polyphenols / therapeutic use; Soybean Proteins; Taste; Vegetables / chemistry; Vitis / chemistry
TL;DR:
Proximate analyses determined that fortification of the soy protein isolate with muscadine or kale bioactives resulted in elevated dietary fibers, total carbohydrates, and free sugars, but did not increase calories/100 g dry matrix compared to unfortified SPI.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
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