Works Published in 2018

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Displaying works 21 - 40 of 106 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2018 journal article

MasterChef at Work: An Interview with Rodolphe Barrangou

The CRISPR Journal, 1(3), 219–222.

Source: ORCID
Added: January 3, 2020

2018 journal article

Expanding the CRISPR Landscape on a cas by cas Basis

The CRISPR Journal, 1(5), 303–303.

By: R. Barrangou*

Source: ORCID
Added: January 3, 2020

2018 journal article

Characterizing the activity of abundant, diverse and active CRISPR-Cas systems in lactobacilli

Scientific Reports, 8(1).

MeSH headings : Bacteriophages / genetics; CRISPR-Cas Systems; Gene Expression Profiling; Genetic Variation; Genome, Bacterial; Lactobacillus / enzymology; Lactobacillus / genetics; Plasmids; RNA, Guide, Kinetoplastida / genetics; Recombination, Genetic
TL;DR: The results reveal that Type II-A systems in lactobacilli are naturally active in their native host in terms of expression and efficiently targeting invasive and genomic DNA, and increase the possible Cas9 targeting space and provide multiplexing potential in native hosts and heterologous genome editing purpose. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: ORCID, Crossref
Added: January 2, 2020

2018 journal article

Effect of adding milk to black tea on vascular function in healthy men and women: a randomised controlled crossover trial

Food & Function, 9(12), 6307–6314.

By: A. Ahmad*, L. Rich*, H. Koch*, K. Croft*, M. Ferruzzi n, C. Kay n, J. Hodgson*, N. Ward*

MeSH headings : Adult; Animals; Blood Pressure; Brachial Artery / physiology; Camellia sinensis / chemistry; Camellia sinensis / metabolism; Cross-Over Studies; Female; Heart Rate; Humans; Male; Milk / metabolism; Tea / metabolism; Vasodilation; Young Adult
TL;DR: The addition of milk to black tea alters the acute/short-term impact of regular tea consumption on vascular function and blood pressure in young healthy men and women. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, ORCID
Added: December 8, 2019

2018 journal article

The Bioavailability, Transport, and Bioactivity of Dietary Flavonoids: A Review from a Historical Perspective

Comprehensive Reviews in Food Science and Food Safety, 17(5), 1054–1112.

author keywords: bioactivity; bioavailability; dietary flavonoids; metabolism; transport
TL;DR: This review traces the development of the field over the past 8 decades, and indicates the current state of the art, and how it was reached. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: December 5, 2019

2018 journal article

Cardiovascular Mechanisms of Action of Anthocyanins May Be Associated with the Impact of Microbial Metabolites on Heme Oxygenase-1 in Vascular Smooth Muscle Cells

Molecules, 23(4), 898.

By: E. Warner*, I. Rodriguez-Ramiro*, M. O’Connell* & C. Kay*

author keywords: anthocyanin; smooth muscle cells; metabolism; antioxidant; atherosclerosis
MeSH headings : Animals; Anthocyanins / chemistry; Anthocyanins / pharmacology; Aorta; Cell Proliferation / drug effects; Cells, Cultured; Gene Expression Regulation / drug effects; Heme Oxygenase (Decyclizing) / metabolism; Molecular Structure; Muscle, Smooth, Vascular / cytology; Muscle, Smooth, Vascular / drug effects; Muscle, Smooth, Vascular / metabolism; Phenols / chemistry; Phenols / pharmacology; Rats; Rats, Sprague-Dawley
TL;DR: It is demonstrated that phenolic metabolites of anthocyanins differentially affect HO-1 activity, often having additive, synergistic or nullifying effects. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: December 5, 2019

2018 journal article

Increased Plasma Levels of Gut-Derived Phenolics Linked to Walking and Running Following Two Weeks of Flavonoid Supplementation

Nutrients.

By: D. Nieman*, C. Kay n, A. Rathore n, M. Grace n, R. Strauch n, E. Stephan*, C. Sakaguchi*, M. Lila n

author keywords: exercise; polyphenol; metabolite; hippurate; intestinal tract; colon
TL;DR: Data indicate that acute exercise bouts (brisk walking, intensive running) are linked to an increased translocation of gut-derived phenolics into circulation, an effect that is amplified when combined with a two-week period of increased flavonoid intake or chronic training as a runner. (via Semantic Scholar)
Source: ORCID
Added: November 13, 2019

2018 article

Increased Plasma Levels of Gut-Derived Phenolics Linked to Walking and Running Following 2-Weeks Flavonoid Supplementation

Nieman, D. C., Kay, C. D., Rathore, A. S., Grace, M. H., Strauch, R. C., Stephan, E. H., … Lila, M. A. (2018, October 15). (Vol. 10). Vol. 10.

By: D. Nieman*, C. Kay n, A. Rathore n, M. Grace n, R. Strauch n, E. Stephan*, C. Sakaguchi*, M. Lila n

Source: ORCID
Added: November 13, 2019

2018 journal article

Computer-aided design and experimental testing of continuous flow cooling of viscous foods

JOURNAL OF FOOD PROCESS ENGINEERING, 41(8).

By: G. Stoforos n & J. Simunovic n

Sources: Web Of Science, ORCID
Added: March 25, 2019

2018 journal article

CRISPRdisco: An Automated Pipeline for the Discovery and Analysis of CRISPR-Cas Systems

CRISPR JOURNAL, 1(2), 171–181.

By: A. Crawley n, J. Henriksan & R. Barranaou

TL;DR: An automated pipeline is developed, named CRISprdisco (CRISPR discovery), to identify CRISPR repeats and cas genes in genome assemblies, determine type and subtype, and describe system completeness, which opens new avenues to enable classification within a complex nomenclature. (via Semantic Scholar)
Sources: ORCID, Web Of Science
Added: February 25, 2019

2018 article

Keep Calm and CRISPR On

Barrangou, R. (2018, February). CRISPR JOURNAL, Vol. 1, pp. 1–3.

By: R. Barrangou*

UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: February 25, 2019

2018 journal article

Enabling the Rise of a CRISPR World

The CRISPR Journal, 1(3), 205–208.

By: C. LaManna n & R. Barrangou n

TL;DR: This work states that a key driver of the technology's adoption is the easy, fast, and inexpensive access to vectors and the resulting next-generation tools by the nonprofit plasmid repository Addgene. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: NC State University Libraries, ORCID
Added: February 18, 2019

2018 journal article

Lack of Evidence for erm(B) Infiltration Into Erythromycin-Resistant Campylobacter coli and Campylobacter jejuni from Commercial Turkey Production in Eastern North Carolina: A Major Turkey-Growing Region in the United States

FOODBORNE PATHOGENS AND DISEASE, 15(11), 698–700.

By: H. Bolinger n, Q. Zhang*, W. Miller* & S. Kathariou n

author keywords: campylobacter; erythromycin; erm(B); turkeys; antimicrobial; resistance
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Campylobacter coli / genetics; Campylobacter coli / isolation & purification; Campylobacter jejuni / genetics; Campylobacter jejuni / isolation & purification; Drug Resistance, Bacterial; Erythromycin / pharmacology; Macrolides / pharmacology; Microbial Sensitivity Tests; North Carolina; RNA, Ribosomal, 23S / genetics; Turkeys / microbiology
TL;DR: Data fail to provide evidence for infiltration of erm(B) into erythromycin-resistant Campylobacter from commercial turkey production in this region and suggest the need for continuing surveillance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: January 28, 2019

2018 personal communication

Disinfectant testing against human norovirus surrogates-What infection preventionists need to know

Clayton, J. S., Bolinger, H. K., & Jaykus, L.-A. (2018, November).

By: J. Clayton, H. Bolinger* & L. Jaykus n

MeSH headings : Caliciviridae Infections / prevention & control; Calicivirus, Feline / drug effects; Disinfectants / pharmacology; Humans; Norovirus / drug effects; United States; United States Environmental Protection Agency; Virus Inactivation / drug effects
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: January 21, 2019

2018 journal article

RNA Helicase Mediates Competitive Fitness of Listeria monocytogenes on the Surface of Cantaloupe

HORTICULTURAE, 4(4).

author keywords: Listeria monocytogenes; competitive fitness; produce; RNA helicase
TL;DR: The findings suggest that the DEAD-box RNA helicase encoded by the lmo0866 homolog is critical for relative fitness of L. monocytogenes on cantaloupe. (via Semantic Scholar)
Source: Web Of Science
Added: January 21, 2019

2018 journal article

A pilot study on nutrients, antimicrobial proteins, and bacteria in commerce-free models for exchanging expressed human milk in the USA

MATERNAL AND CHILD NUTRITION, 14.

By: M. Perrin n, A. Fogleman n, D. Davis n, C. Wimer n, K. Vogel n & A. Palmquist*

author keywords: human milk analysis; milk sharing; peer-to-peer milk sharing
MeSH headings : Anti-Infective Agents / analysis; Bacteria, Aerobic / isolation & purification; Breast Milk Expression; Enterobacteriaceae / isolation & purification; Fats / analysis; Female; Humans; Immunoglobulin A / analysis; Lactose / analysis; Milk Banks; Milk Proteins / analysis; Milk, Human / chemistry; Milk, Human / microbiology; Muramidase / analysis; Nutrients / analysis; Pilot Projects; Staphylococcus aureus / isolation & purification; Tissue Donors
TL;DR: Evaluating the macronutrient, antimicrobial protein, and bacteria composition in expressed human milk acquired via commerce-free arrangements contributes to growing literature on the risks and benefits of uncompensated, peer-to-peer milk sharing. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: January 14, 2019

2018 journal article

Deletion-based escape of CRISPR-Cas9 targeting in Lactobacillus gasseri

MICROBIOLOGY-SGM, 164(9), 1098–1111.

By: E. Stout n, R. Sanozky-Dawes n, Y. Goh n, A. Crawley n, T. Klaenhammer n & R. Barrangou n

author keywords: Lactobacillus; CRISPR; Cas; Cas9; interference; spacer
MeSH headings : CRISPR-Associated Protein 9 / metabolism; Clustered Regularly Interspaced Short Palindromic Repeats; Interspersed Repetitive Sequences; Lactobacillus gasseri / genetics; Mutation; Plasmids; Recombination, Genetic; Sequence Deletion; Transformation, Bacterial
TL;DR: It is shown that deletions of spacers within CRISPR arrays constitute a key escape mechanism to evadeCRISPR targeting, while preserving the functionality of the CRISpr-Cas system. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: December 31, 2018

2018 article

Next generation microbiological risk assessment-Potential of omics data for hazard characterisation

Haddad, N., Johnson, N., Kathariou, S., Metris, A., Phister, T., Pielaat, A., … Zwietering, M. H. (2018, December 20). INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, Vol. 287, pp. 28–39.

By: N. Haddad*, N. Johnson*, S. Kathariou n, A. Metris*, T. Phister*, A. Pielaat*, C. Tassou, M. Wells-Bennikh, M. Zwietering*

author keywords: Dose-response; Virulence; Pathogenicity; Functional genomics; Quantitative transcriptomics and proteomics; Risk analysis; Food safety; Public health
MeSH headings : Biomarkers; Computational Biology; Food Microbiology / standards; Food Microbiology / trends; Genomics; Humans; Metabolomics; Microbiota / genetics; Proteomics; Risk Assessment; Systems Biology
TL;DR: How Next Generation Omics can impact hazard characterisation and, more precisely, how it can improve the understanding of variability and limit the uncertainty in the dose-response relation is discussed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: December 10, 2018

2018 article

Next generation microbiological risk assessment: opportunities of whole genome sequencing (WGS) for foodborne pathogen surveillance, source tracking and risk assessment

Rantsiou, K., Kathariou, S., Winkler, A., Skandamis, P., Saint-Cyr, M. J., Rouzeau-Szynalski, K., & Amezquita, A. (2018, December 20). INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, Vol. 287, pp. 3–9.

By: K. Rantsiou*, S. Kathariou n, A. Winkler*, P. Skandamis*, M. Saint-Cyr*, K. Rouzeau-Szynalski*, A. Amezquita*

author keywords: Whole genome sequencing; Surveillance; Epidemiology; Foodborne pathogens; Source tracking
MeSH headings : Food Safety; Foodborne Diseases / microbiology; Foodborne Diseases / prevention & control; Genome, Bacterial / genetics; Humans; Public Health; Risk Assessment / trends; Whole Genome Sequencing
TL;DR: The contribution of WGS in diverse areas important to food safety and public health and an outlook of future WGS applications, which should contribute to the understanding of the ecology and physiology of foodborne microorganisms, are discussed. (via Semantic Scholar)
Source: Web Of Science
Added: December 10, 2018

2018 journal article

Nutritional Comparison of Raw, Holder Pasteurized, and Shelf-stable Human Milk Products

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 67(5), 649–653.

By: H. Lima n, K. Vogel n, M. Wagner-Gillespie n, C. Wimer n, L. Dean n & A. Fogleman n

author keywords: commercial sterilization; donor human milk; heat processing; infant nutrition
MeSH headings : Dietary Fats / analysis; Food Handling / methods; Humans; Lactose / analysis; Lysine / analysis; Milk Proteins / analysis; Milk, Human / chemistry; Nutritive Value; Pasteurization / methods; Raw Foods / analysis; Thiamine / analysis
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: December 10, 2018

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