Works Published in 2014

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Displaying works 41 - 60 of 125 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2014 journal article

Prevalence of Rickettsiales in ticks removed from the skin of outdoor workers in North Carolina

PARASITES & VECTORS, 7.

By: S. Lee n, M. Kakumanu n, L. Ponnusamy n, M. Vaughn*, S. Funkhouser*, H. Thornton n, S. Meshnick*, C. Apperson n

author keywords: Ticks; Rickettsiales pathogens; Rickettsia; Ehrlichia; Reverse line blot hybridization
MeSH headings : Animals; Arachnid Vectors / microbiology; Base Sequence; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; DNA, Ribosomal / chemistry; DNA, Ribosomal / genetics; Double-Blind Method; Female; Humans; Ixodidae / microbiology; Male; Molecular Sequence Data; North Carolina / epidemiology; Polymerase Chain Reaction; Prevalence; Rickettsia / genetics; Rickettsia / isolation & purification; Rickettsia Infections / epidemiology; Rickettsia Infections / microbiology; Sequence Analysis, DNA; Tick Infestations / epidemiology
TL;DR: It is concluded that in North Carolina, the most common rickettsial exposure is to R. amblyommii carried by A. americanum, and Rickettsiales bacteria, including novel species of Rickettsia, were less frequently detected in A.Americanum. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Microbiological analysis of environmental samples collected from child care facilities in North and South Carolina

AMERICAN JOURNAL OF INFECTION CONTROL, 42(10), 1049–1055.

By: Y. Li n, A. Fraser*, . Chen*, S. Cates*, K. Wohlgenant* & L. Jaykus n

author keywords: Childcare facilities; Day care; Environmental sampling; Microbiological indicators; Enteric pathogens
MeSH headings : Bacteria / isolation & purification; Caregivers; Child Day Care Centers; Child, Preschool; Environmental Microbiology; Female; Hand / microbiology; Hand / virology; Humans; Infant; Infection Control / methods; Male; Norovirus / isolation & purification; North Carolina; South Carolina
TL;DR: The relative absence of pathogens and biotype I E coli in environmental samples suggests the child care facilities sampled in this study managed fecal contamination well. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 article

A need for a transdisciplinary environment: the Plant Pathways Elucidation Project

Reid, R. W., Brouwer, C. R., Jackson, E. W., & Lila, M. A. (2014, August). TRENDS IN PLANT SCIENCE, Vol. 19, pp. 485–487.

By: R. Reid, C. Brouwer, E. Jackson* & M. Lila n

MeSH headings : Humans; Industry; Interdisciplinary Communication; Knowledge Bases; Metabolic Networks and Pathways; Plants / metabolism; Universities
TL;DR: The Plant Pathways Elucidation Project (P2EP) is a multi-institutional project that utilizes cutting-edge genomics research and related disciplines to provide greater understanding of the relation between plant-pathway products and human health. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 article

A CRISPR design for next-generation antimicrobials

GENOME BIOLOGY, Vol. 15.

By: C. Beisel n, A. Gomaa n & R. Barrangou n

MeSH headings : Animals; Anti-Infective Agents / administration & dosage; CRISPR-Cas Systems; Drug Resistance, Microbial / genetics; Enterohemorrhagic Escherichia coli / genetics; Gene Targeting; RNA, Guide, Kinetoplastida / genetics; Ribonucleases / genetics
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2014 journal article

Tracing Temperature Patterns of Cut Leafy Greens during Service in North Carolina School Food Service

JOURNAL OF FOOD PROTECTION, 77(9), 1495–1500.

By: E. Thomas*, B. Chapman n, L. Jaykus* & T. Phister*

MeSH headings : Food Contamination / analysis; Food Handling / instrumentation; Food Handling / methods; Food Handling / standards; Food Services / standards; Humans; Lettuce / microbiology; North Carolina; Plant Leaves / microbiology; Schools / statistics & numerical data; Spinacia oleracea / microbiology; Temperature; Vegetables / microbiology
TL;DR: The results demonstrate the importance of developing a protocol for continuous temperature monitoring of leafy greens served in school lunch programs and demonstrate the two policies that North Carolina has in place to control the temperature of these products. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 journal article

The three major types of CRISPR-Cas systems function independently in CRISPR RNA biogenesis in Streptococcus thermophilus

MOLECULAR MICROBIOLOGY, 93(1), 98–112.

By: J. Carte*, R. Christopher*, J. Smith*, S. Olson*, R. Barrangou n, S. Moineau*, C. Glover*, B. Graveley*, R. Terns*, M. Terns*

MeSH headings : Bacterial Proteins / metabolism; CRISPR-Cas Systems; Models, Genetic; RNA, Bacterial / metabolism; Sequence Analysis, RNA; Streptococcus thermophilus / genetics; Streptococcus thermophilus / metabolism
TL;DR: Investigation of the features and biogenesis of the CRISPR (cr)RNAs in Streptococcus thermophilus (Sth) strain DGCC7710 indicates that multipleCRISPR‐Cas systems can function independently in crRNA biogenesis within a given organism. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2014 journal article

Peanut fractions boost the growth of Lactobacillus casei that alters the interactions between Campylobacter jejuni and host epithelial cells

FOOD RESEARCH INTERNATIONAL, 62, 1141–1146.

By: S. Salaheen, B. White n, B. Bequette* & D. Biswas*

author keywords: Probiotic; Fatty acid; Peanut; Campylobacteriosis; Co-culture
TL;DR: It is hypothesize that regular consumption of peanuts may positively impact on the composition of human gut microbiota and decrease the burden of gastrointestinal infections by enteric bacterial pathogens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Novel Strategy To Create Hypoallergenic Peanut Protein-Polyphenol Edible Matrices for Oral Immunotherapy

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 62(29), 7010–7021.

By: N. Plundrich n, M. Kulis*, B. White, M. Grace n, R. Guo*, A. Burks*, J. Davis, M. Lila n

author keywords: basophil; cranberry; mouse model; peanut allergy; polyphenols
MeSH headings : Administration, Oral; Arachis / immunology; Arachis / metabolism; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Humans; Immunotherapy; Peanut Hypersensitivity / prevention & control; Plant Proteins / administration & dosage; Plant Proteins / immunology; Polyphenols / administration & dosage; Polyphenols / immunology; Spectroscopy, Fourier Transform Infrared
TL;DR: Polyphenol fortification of peanut flour resulted in a hypoallergenic matrix with reduced IgE binding and degranulation capacity, likely due to changes in protein secondary structure or masking of epitopes, suggesting potential applications for oral immunotherapy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Inhibitory Effects of Wild Blueberry Anthocyanins and Other Flavonoids on Biomarkers of Acute and Chronic Inflammation in Vitro

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 62(29), 7022–7028.

By: D. Esposito n, A. Chen n, M. Grace n, S. Komarnytsky n & M. Lila n

author keywords: Vaccinium angustifolium; lowbush blueberry; polyphenols; proanthocyanidins; chlorogenic acid
MeSH headings : Acute Disease; Animals; Anthocyanins / pharmacology; Base Sequence; Biomarkers / metabolism; Blueberry Plants / chemistry; Cell Line; Chromatography, High Pressure Liquid; Chronic Disease; DNA Primers; In Vitro Techniques; Inflammation / metabolism; Macrophages / drug effects; Macrophages / metabolism; Mice; Polymerase Chain Reaction
TL;DR: Among major polyphenols found in the wild blueberries, malvidin-3-glucoside was significantly more effective than epicatechin or chlorogenic acid in reducing the expression of pro-inflammatory genes in vitro. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Impact of Oil-in-Water Emulsion Composition and Preparation Method on Emulsion Physical Properties and Friction Behaviors

TRIBOLOGY LETTERS, 56(1), 143–160.

author keywords: Soft tribology; Food; Emulsion; Physical properties
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Guide RNA Functional Modules Direct Cas9 Activity and Orthogonality

MOLECULAR CELL, 56(2), 333–339.

By: A. Briner n, P. Donohoue*, A. Gomaa n, K. Selle n, E. Slorach*, C. Nye*, R. Haurwitz*, C. Beisel n, A. May*, R. Barrangou n

MeSH headings : Bacterial Proteins / chemistry; CRISPR-Associated Protein 9; CRISPR-Associated Proteins / chemistry; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; DNA / chemistry; DNA Cleavage; Endonucleases / chemistry; Genetic Engineering / methods; HEK293 Cells; Humans; Nucleic Acid Conformation; RNA, Guide, Kinetoplastida / chemistry; RNA, Guide, Kinetoplastida / genetics; RNA, Guide, Kinetoplastida / ultrastructure
TL;DR: Six conserved modules within native crRNA:tracrRNA duplexes and single guide RNAs that direct Cas9 endonuclease activity are identified and characterized and it is shown the bulge and nexus are necessary for DNA cleavage and the nexus and hairpins are instrumental in defining orthogonality between systems. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2014 journal article

Genomic Encyclopedia of Type Strains of the Genus Bifidobacterium

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 80(20), 6290–6302.

By: C. Milani*, G. Lugli*, S. Duranti*, F. Turroni*, F. Bottacini*, M. Mangifesta*, B. Sanchez*, A. Viappiani* ...

MeSH headings : Animals; Bifidobacterium / genetics; Bifidobacterium / metabolism; Bifidobacterium / physiology; Biological Evolution; Clustered Regularly Interspaced Short Palindromic Repeats; Computer Simulation; Gastrointestinal Tract / microbiology; Genome, Bacterial; Molecular Sequence Data; Phylogeny; Sequence Analysis, DNA; Species Specificity
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2014 journal article

Genetic Characterization of Plasmid-Associated Triphenylmethane Reductase in Listeria monocytogenes

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 80(17), 5379–5385.

MeSH headings : Benzalkonium Compounds / metabolism; Benzalkonium Compounds / toxicity; Biotransformation; DNA Transposable Elements; Gene Order; Gentian Violet / metabolism; Gentian Violet / toxicity; Listeria monocytogenes / enzymology; Listeria monocytogenes / genetics; Listeria monocytogenes / isolation & purification; Oxidation-Reduction; Oxidoreductases / genetics; Oxidoreductases / metabolism; Plasmids; Rosaniline Dyes / metabolism; Rosaniline Dyes / toxicity; Trityl Compounds / metabolism
TL;DR: A potential role of TMR as a previously unknown adaptive attribute for environmental persistence of L. monocytogenes is suggested. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Cytotoxic Effects of Ellagitannins Isolated from Walnuts in Human Cancer Cells

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 66(8), 1304–1314.

By: V. Le*, D. Esposito n, M. Grace n, D. Ha*, A. Pham*, A. Bortolazzo*, Z. Bevens*, J. Kim* ...

MeSH headings : 3T3 Cells; Animals; Apoptosis / drug effects; Cell Line, Tumor; Cyclin B1 / metabolism; Cytochromes c / metabolism; Diet; HeLa Cells; Humans; Hydrogen-Ion Concentration; Hydrolyzable Tannins / pharmacology; Juglans / chemistry; MCF-7 Cells; Mice; Mice, Nude; Mitochondria / drug effects; Nuts / chemistry; Plant Extracts / pharmacology
TL;DR: The results suggest impairment of mitochondrial function and apoptosis as relevant mechanism of anticancer effects of the walnut extract as well as antimitogenic effects of walnuts. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Sanitation in classroom and food preparation areas in child-care facilities in North Carolina and South Carolina

Journal of Environmental Health, 77(4), 20–27.

By: K. Wohlgenant, S. Cates, A. Fraser, B. Chapman, L. Jaykus & X. Chen

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Phlorotannins from Alaskan Seaweed Inhibit Carbolytic Enzyme Activity

MARINE DRUGS, 12(10), 5277–5294.

By: J. Kellogg n, M. Grace n & M. Lila n

author keywords: Alaska; seaweed; diabetes; glucosidase; hyperglycemia; amylase; type 2 diabetes mellitus; phlorotannin; polyphenol; ethnopharmacology
MeSH headings : Animals; Biological Factors / metabolism; Biological Factors / pharmacology; Carbohydrates; Enzyme Inhibitors / metabolism; Enzyme Inhibitors / pharmacology; Fucus / metabolism; Kinetics; Saccharomyces cerevisiae / metabolism; Seaweed / metabolism; Swine / metabolism; Tannins / metabolism; Tannins / pharmacology; alpha-Amylases / antagonists & inhibitors; alpha-Glucosidases / metabolism
TL;DR: It is suggested that coastal Alaskan seaweeds are sources of α-glucosidase and α-amylase inhibitory phlorotannins, and thus have potential to limit the release of sugar from carbohydrates and thus alleviate postprandial hyperglycemia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Ligularia fischeri Extract Protects Against Oxidative-Stress-Induced Neurotoxicity in Mice and PC12 Cells

JOURNAL OF MEDICINAL FOOD, 17(11), 1222–1231.

By: S. Choi n, J. Kim*, S. Suh n, C. Kim*, H. Kim*, C. Kim*, G. Park*, C. Park*, D. Shin*

author keywords: Ligularia fischeri; amyloid beta peptide; 3-O-caffeoylquinic acid; oxidative stress
MeSH headings : Alzheimer Disease / metabolism; Alzheimer Disease / prevention & control; Amyloid beta-Peptides / metabolism; Amyloid beta-Peptides / toxicity; Animals; Antioxidants / pharmacology; Antioxidants / therapeutic use; Asteraceae / chemistry; Avoidance Learning / drug effects; Brain / drug effects; Chlorogenic Acid / pharmacology; Chlorogenic Acid / therapeutic use; Cognition Disorders / chemically induced; Cognition Disorders / genetics; Cognition Disorders / prevention & control; DNA Fragmentation / drug effects; Hydrogen Peroxide / metabolism; Hydrogen Peroxide / toxicity; Learning Disabilities / chemically induced; Learning Disabilities / prevention & control; Lipid Peroxidation / drug effects; Male; Memory / drug effects; Memory Disorders / chemically induced; Memory Disorders / prevention & control; Mice, Inbred ICR; Neuroprotective Agents / pharmacology; Neuroprotective Agents / therapeutic use; Neurotoxicity Syndromes / genetics; Neurotoxicity Syndromes / prevention & control; Oxidative Stress / drug effects; PC12 Cells; Phytotherapy; Plant Extracts / pharmacology; Plant Extracts / therapeutic use; Rats
TL;DR: Results suggest that L. fischeri extract could be protective against Aβ-induced neurotoxicity, possibly due to the antioxidative capacity of its constituent, 3-O-caffeoylquinic acid. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 article

Enzymatic bleaching in commercial colored Cheddar whey retentates

Campbell, R. E., & Drake, M. A. (2014, October). INTERNATIONAL DAIRY JOURNAL, Vol. 38, pp. 148–153.

UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 journal article

DETERMINING CHILDREN'S PERCEPTIONS, OPINIONS AND ATTITUDES FOR SLICED SANDWICH BREADS

JOURNAL OF SENSORY STUDIES, 29(5), 351–361.

UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 conference paper

Capitalizing on the health benefits of berryfruit: Science versus the marketplace

Ii international symposium on biotechnology of fruit species, 1048, 123–128.

By: M. Lila n

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

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