Works Published in 2019
Displaying works 41 - 60 of 133 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2019 journal article
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells
NATURE BIOTECHNOLOGY, 37(12), 1493-+.
MeSH headings : CRISPR-Cas Systems / genetics; Escherichia coli / genetics; Genetic Engineering / methods; HEK293 Cells; Humans; Listeria monocytogenes / genetics; RNA, Guide, Kinetoplastida / genetics; Transcription, Genetic / genetics
TL;DR:
This study repurposes type I variants of class 1 CRISPR–Cas systems from Escherichia coli and Listeria monocytogenes, which target DNA via a multi-component RNA-guided complex termed Cascade, and demonstrates the use of Cascade as a CRISpr-based technology for targeted eukaryotic gene regulation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: December 30, 2019
2019 journal article
Gut microbiota dysbiosis in a cohort of patients with psoriasis
BRITISH JOURNAL OF DERMATOLOGY, 181(6), 1287–1295.
MeSH headings : Adult; Cohort Studies; DNA, Bacterial / isolation & purification; Dysbiosis / complications; Dysbiosis / diagnosis; Dysbiosis / immunology; Dysbiosis / microbiology; Feces / microbiology; Female; Gastrointestinal Microbiome / genetics; Gastrointestinal Microbiome / immunology; Healthy Volunteers; Humans; Male; Middle Aged; Psoriasis / immunology; Psoriasis / microbiology; RNA, Ribosomal, 16S / genetics
TL;DR:
There is increasing evidence of the key role that the gut microbiota plays in inflammatory diseases and the importance of knowing your gut microbiota to understand and treat inflammatory diseases is increasing.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: December 30, 2019
2019 journal article
Steeping of Biofortified Orange Maize Genotypes for Ogi Production Modifies Pasting Properties and Carotenoid Stability
AGRONOMY-BASEL, 9(11).
author keywords: biofortified maize; pro-vitamin A; lutein; zeaxanthin; carotenoids; degradation; retention; steeping; fermentation; food processing; nutritional impact
www.mdpi.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: December 30, 2019
2019 journal article
Requirement of lmo1930, a Gene in the Menaquinone Biosynthesis Operon, for Esculin Hydrolysis and Lithium Chloride Tolerance in Listeria monocytogenes
MICROORGANISMS, 7(11).
author keywords: esculin; Listeria monocytogenes; menaquinone; selective enrichment
TL;DR:
Transposon-based inactivation of lmo1930, one of the genes in the menaquinone biosynthesis operon, via transposon mutagenesis severely impaired the ability of L. monocytogenes to grow in the presence of lithium chloride or hydrolyze esculin, and conferred reduced growth and colony size.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: December 30, 2019
2019 article
Predicting and visualizing features of CRISPR-Cas systems
CRISPR-CAS ENZYMES, Vol. 616, pp. 1–25.
MeSH headings : Animals; Bacteria / genetics; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; Computer Simulation; Gene Editing / methods; Genomics / methods; Humans; RNA, Guide, Kinetoplastida / genetics; Software
TL;DR:
In silico methods for predicting and visualizing notable features of CRISPR-Cas systems, including Cas domain determination,CRISPR array visualization, and inference of the protospacer-adjacent motif are described.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: December 30, 2019
2019 journal article
Strain-Specific Differences in Survival of Campylobacter spp. in Naturally Contaminated Turkey Feces and Water
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 85(22).
author keywords: Campylobacter; Campylobacter coli; Campylobacter jejuni; turkey; antimicrobial resistance; feces; survival; water
MeSH headings : Animals; Bacterial Typing Techniques; Campylobacter / classification; Campylobacter / physiology; Campylobacter Infections / microbiology; Campylobacter Infections / veterinary; Campylobacter coli / physiology; Campylobacter jejuni / physiology; Cold Temperature; Drug Resistance, Multiple, Bacterial; Feces / microbiology; Microbial Viability; Multilocus Sequence Typing; Polymorphism, Restriction Fragment Length; Turkeys; Water Microbiology
TL;DR:
Examination of survival of Campylobacter, including different strains, in freshly excreted feces from naturally colonized commercial turkey flocks and in suspensions of turkey feces in water from the turkey house revealed that C. jejuni survived longer than C. coli in feces, while the reverse was observed in water.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: December 16, 2019
2019 journal article
Comparative genomics of eight Lactobacillus buchneri strains isolated from food spoilage
BMC GENOMICS, 20(1).
author keywords: Lactobacillus buchneri; Comparative genomics; Lactic acid bacteria; CRISPR-Cas systems; Fermentation; Spoilage; Food microbiology
MeSH headings : Computational Biology / methods; Evolution, Molecular; Fermentation; Food Microbiology; Genome, Bacterial; Genomics / methods; Lactobacillus / classification; Lactobacillus / genetics; Lactobacillus / isolation & purification; Molecular Sequence Annotation; Phylogeny; Whole Genome Sequencing
TL;DR:
The findings from the comparison of eight newly-sequenced and assembled genomes against two publicly available closed reference genomes provide new insights into the genomics of L. buchneri, building a platform for future studies and identifying elements for potential strain manipulation or engineering.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: December 16, 2019
2019 journal article
A qualitative exploration of potential determinants of accelerated summer weight gain among school-age children: perspectives from parents
BMC PEDIATRICS, 19(1).
author keywords: Child obesity; Summer weight gain; Diet; Physical activity; Parents; Qualitative research
MeSH headings : Child; Diet; Exercise; Female; Humans; Interviews as Topic; Male; Massachusetts; Parents; Seasons; Weight Gain
TL;DR:
Parents perceived their children to be more physically active in the summer and consume more fruits and vegetables than during the school year, however, they also perceived children to consume more energy-dense, nutrient poor foods, engage in more screen time, and have later bedtimes during the summer, which are important targets for summertime obesity prevention interventions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: December 9, 2019
2019 journal article
Draft Genome Sequence of Multidrug-Resistant Listeria innocua Strain UAM003-1A, Isolated from a Wild Black Bear (Ursus americanus)
MICROBIOLOGY RESOURCE ANNOUNCEMENTS, 8(47).
TL;DR:
The draft genome sequence and associated genome information of an antibiotic-resistant Listeria innocua strain, UAM003-1A, isolated from the feces of a black bear in California, USA is reported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Source: Web Of Science
Added: December 9, 2019
2019 journal article
Blueberries improve biomarkers of cardiometabolic function in participants with metabolic syndrome—results from a 6-month, double-blind, randomized controlled trial
The American Journal of Clinical Nutrition, 109(6), 1535–1545.
author keywords: metabolic syndrome; blueberry anthocyanins; flavonoids; cardiovascular disease risk; anthocyanin-derived phenolic acid metabolites
MeSH headings : Aged; Apolipoproteins / blood; Biomarkers / blood; Blood Pressure; Blueberry Plants / metabolism; Cholesterol, HDL / blood; Cholesterol, LDL / blood; Double-Blind Method; Female; Fruit / metabolism; Heart / physiopathology; Humans; Insulin Resistance; Male; Metabolic Syndrome / blood; Metabolic Syndrome / diet therapy; Metabolic Syndrome / physiopathology; Middle Aged; Prospective Studies; Pulse Wave Analysis
TL;DR:
Despite insulin resistance remaining unchanged, blueberries should be included in dietary strategies to reduce individual and population CVD risk, and first sustained improvements in vascular function, lipid status, and underlying NO bioactivity following 1 cup blueberries/d are shown.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: December 5, 2019
2019 article
Casein as a Modifier of Whey Protein Isolate Gel: Sensory Texture and Rheological Properties
JOURNAL OF FOOD SCIENCE.
MeSH headings : Caseins / chemistry; Caseins / metabolism; Elasticity; Gels / chemistry; Gels / metabolism; Hot Temperature; Humans; Mastication; Rheology; Taste; Whey Proteins / chemistry; Whey Proteins / metabolism
TL;DR:
It was demonstrated that casein can be used to alter whey protein gel structure such that sensory firmness and fracturability are decreased and cohesiveness is increased, while preventing a large increase in moisture release.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: December 2, 2019
2019 article
Blueberries Topical Application Prevents Ozone Induced Cutaneous Inflammasome Activation
Pambianchi, E., Francesca, F., Pecorelli, A., Woodby, B., Lila, M., & Valacchi, G. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S148–S148.
Sources: Web Of Science, NC State University Libraries
Added: December 2, 2019
2019 article
Listeria monocytogenes at the human-wildlife interface: black bears (Ursus americanus) as potential vehicles for Listeria
MICROBIAL BIOTECHNOLOGY.
MeSH headings : Animals; Animals, Wild / microbiology; Listeria monocytogenes / isolation & purification; Listeria monocytogenes / physiology; Listeriosis / epidemiology; Listeriosis / microbiology; Listeriosis / transmission; Southeastern United States / epidemiology; Ursidae / microbiology
TL;DR:
The results suggest that the ursine host may preferentially select for L. monocytogenes of clinically relevant lineages over the diverse listerial populations in the environment, and highlight the public health significance of the human–wildlife interface.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: November 25, 2019
2019 journal article
Teachers' perceptions of sustainable integration of garden education into Head Start classrooms: A grounded theory approach
JOURNAL OF EARLY CHILDHOOD RESEARCH, 17(4), 392–407.
author keywords: early childhood education; garden education; grounded theory; Head Start; preschool teachers; qualitative research methods
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
4. Quality Education
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 25, 2019
2019 journal article
Contribution of Berry Polyphenols to the Human Metabolome
Molecules.
author keywords: mass spectrometry; metabolome; metabolomics; microbiome; (poly)phenol
MeSH headings : Anthocyanins / chemistry; Anthocyanins / pharmacokinetics; Blueberry Plants / chemistry; Fragaria / chemistry; Fruit / chemistry; Humans; Metabolome; Polyphenols / chemistry; Polyphenols / pharmacokinetics
TL;DR:
Berry consumption in general appears to cause a fluctuation in the pools of small molecule metabolites already present at baseline, rather than the appearance of unique berry-derived metabolites, which likely reflects the ubiquitous nature of (poly)phenols in the background diet.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: November 25, 2019
2019 journal article
One thousand plant transcriptomes and the phylogenomics of green plants
NATURE, 574(7780), 679-+.
TL;DR:
It is found that large expansions of gene families preceded the origins of green plants, land plants and vascular plants, whereas whole-genome duplications are inferred to have occurred repeatedly throughout the evolution of flowering plants and ferns.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science; OpenAlex)
Source: Web Of Science
Added: November 18, 2019
2019 article
Collaborative networks in gene editing
Huang, Y., Porter, A., Zhang, Y., & Barrangou, R. (2019, October). NATURE BIOTECHNOLOGY, Vol. 37, pp. 1107–1109.
MeSH headings : Biomedical Research / trends; Gene Editing; Humans; International Cooperation; Leadership; Publishing / trends
TL;DR:
Of the literature on gene-editing modalities, CRISPR–Cas continues to grow, whereas publications describing meganucleases, zinc finger nucleases and transcription activator–like effector nuclease (TALENs) have been decreasing since 2016.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 18, 2019
2019 journal article
Efficient stabilisation of curcumin microencapsulated into yeast cells via osmoporation
Applied Microbiology and Biotechnology, 103(23-24), 9659–9672.
author keywords: Curcumin; Osmoporation; S; cerevisiae; Antioxidant activity; Stability; Microencapsulation
MeSH headings : Cell Membrane Permeability; Curcumin / chemistry; Ethanol; Industrial Microbiology / methods; Osmotic Pressure; Saccharomyces cerevisiae / metabolism
TL;DR:
Results showed that encapsulation efficiency was favoured by the increase of cells/curcumin ratio and ethanol concentration up to 60%.
(via Semantic Scholar)
Source: ORCID
Added: November 12, 2019
2019 journal article
Estimation of Ascorbic Acid in Intact Acerola (<i>Malpighia emarginata</i> DC) Fruit by NIRS and Chemometric Analysis
Horticulturae.
author keywords: Acerola; NIRS; PLS; iPLS; GA-PLS; ascorbic acid
TL;DR:
A non-destructive, reliable, and fast method to measure the ascorbic acid content in intact acerola, using near-infrared spectroscopy (NIRS) associated with multivariate calibration methods and chemometrics.
(via Semantic Scholar)
Source: ORCID
Added: November 12, 2019
2019 journal article
Contamination of eggs by Salmonella Enteritidis in experimentally infected laying hens of four commercial genetic lines in conventional cages and enriched colony housing
POULTRY SCIENCE, 98(10), 5023–5027.
author keywords: Salmonella Enteritidis; laying hens; eggs; housing systems; genetic lines
MeSH headings : Animal Husbandry; Animals; Chickens / genetics; Color; Female; Housing, Animal; Incidence; North Carolina / epidemiology; Ovum / microbiology; Ovum / physiology; Pigmentation; Poultry Diseases / epidemiology; Poultry Diseases / microbiology; Salmonella Infections, Animal / epidemiology; Salmonella Infections, Animal / microbiology; Salmonella enteritidis / physiology
TL;DR:
Results demonstrate that S. Enteritidis deposition inside eggs can vary between genetic lines of infected laying hens, but housing these hens in 2 different systems did not affect the production of contaminated eggs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: November 4, 2019
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