Works Published in 2012

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Displaying works 1 - 20 of 111 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2012 conference paper

Isolation processes for Bovine Milk Fat Globules (MFGs) induce structural and compositional changes

Presented at the Riddet Institute Research Colloquium, Palmerston North, New Zealand.

By: H. Zheng

Event: Riddet Institute Research Colloquium at Palmerston North, New Zealand

Source: NC State University Libraries
Added: September 30, 2021

2012 journal article

P3-342: Intranasal delivery of bioactive polyphenol metabolites to prevent and/or treat Alzheimer's disease and other forms of dementia

Alzheimer's & Dementia, 8(4S_Part_16), P577–P577.

By: L. Knable*, P. Vempati*, D. Freire*, M. Ferruzzi* & G. Pasinetti*

Source: Crossref
Added: August 16, 2021

2012 journal article

Different concentrations of grape seed extract affectin vitrostarch fermentation by porcine small and large intestinal inocula

Journal of the Science of Food and Agriculture, 93(2), 276–283.

author keywords: Grape seed extract; pig; intestinal microbiota; in vitro fermentation; short-chain fatty acids; cumulative gas production; ammonia
MeSH headings : Ammonia / metabolism; Animals; Dietary Supplements; Fatty Acids, Volatile / metabolism; Feces / microbiology; Fermentation; Gastrointestinal Agents / metabolism; Gram-Negative Bacteria / isolation & purification; Gram-Negative Bacteria / metabolism; Gram-Positive Bacteria / isolation & purification; Gram-Positive Bacteria / metabolism; Grape Seed Extract / metabolism; Ileum / microbiology; Intestine, Large / microbiology; Intestine, Small / microbiology; Kinetics; Queensland; Seeds / chemistry; Starch / metabolism; Sus scrofa / microbiology; Vitis / chemistry
TL;DR: It is shown that GSE phenolics at a concentration over 250 µg ml⁻¹ can have measurable effects on microbial activity in an in vitro fermentation system, as evidenced by the changes in kinetics and end-products from starch fermentation. (via Semantic Scholar)
Source: Crossref
Added: January 24, 2021

2012 journal article

Continuous Infusion of 20-Hydroxyecdysone Increased Mass of Triceps Brachii in C57BL/6 Mice

Phytotherapy Research, 27(1), 107–111.

By: D. Cheng*, L. Kutzler*, D. Boler*, J. Drnevich*, J. Killefer* & M. Lila*

author keywords: 20-hydroxyecdysone; infusion; mice; microarray; phytoecdysteroids; skeletal muscle
MeSH headings : Anabolic Agents / pharmacology; Animals; Ecdysterone / pharmacology; Gene Expression; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal / drug effects; Muscle, Skeletal / physiology; Oligonucleotide Array Sequence Analysis; Organ Size; Transcriptome
TL;DR: Overall, the data suggest that 20E does not have potent anabolic properties, however, a muscle‐specific increase was observed and genes were identified to provide an explanation for the muscle accretion. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 21, 2021

2012 journal article

Porcine parvovirus removal using trimer and biased hexamer peptides

Biotechnology Journal, 7(4), 558–565.

By: C. Heldt n, P. Gurgel n, L. Jaykus n & R. Carbonell n

author keywords: Affinity adsorption; Biosafety; Bioseparation; Ligand; Virus removal
MeSH headings : Adsorption; Chromatography, Affinity; Humans; Parvovirus, Porcine / chemistry; Parvovirus, Porcine / isolation & purification; Peptides / chemical synthesis; Peptides / chemistry; Plasma / chemistry; Plasma / virology
TL;DR: This study demonstrates that trimeric and hexameric peptides may have different, matrix‐specific roles to play in virus removal applications, and in general, the hexamer ligand may perform better for binding of specific viruses, whereas the trimer ligand might have more broadly reactive virus‐binding properties. (via Semantic Scholar)
Source: Crossref
Added: January 14, 2021

2012 journal article

Synthesis of [6, 8, 10, 3’, 5’-C-13 (5)]-cyanidin-3-glucoside, for human in vivo metabolism studies

Journal of Labelled Compounds & Radiopharmaceuticals, 55(3), 131–132.

By: Q. Zhang, N. Botting & C. Kay

Source: NC State University Libraries
Added: November 6, 2020

2012 journal article

Effects of pistachios and walnuts on hemodynamic reactivity to stress: Clinical trials in adults with dyslipidemia

Australasian Medical Journal (Online, 5(12), 676.

By: S. West, S. Gebauer, C. Kay, A. Skulas-Ray & P. Kris-Etherton

Source: NC State University Libraries
Added: November 6, 2020

2012 journal article

Cucurbitacin glycosides from Datisca glomerata with antiplasmodial activity

Planta Medica, 78(11).

By: R. Graziose*, M. Grace n, T. Rathinasabapathy*, P. Rojas-Silva*, C. Dekock*, A. Poulev*, M. Lila n, P. Smith*, I. Raskin*

Source: Crossref
Added: September 9, 2020

2012 journal article

Seeking novel Leishmanicidal natural products from common medicinal plants, the example of Eryngium foetidum L

Planta Medica, 78(11).

By: P. Rojas-Silva*, R. Graziose*, A. Poulev*, F. Mbeunkui n, M. Grace n, M. Lila n, I. Raskin*

Source: Crossref
Added: September 9, 2020

2012 journal article

In vitro and in vivo anti-diabetic effects of anthocyanins from Maqui Berry (Aristotelia chilensis)

Food Chemistry, 131(2), 387–396.

By: L. Rojo*, D. Ribnicky*, S. Logendra*, A. Poulev*, P. Rojas-Silva*, P. Kuhn*, R. Dorn*, M. Grace n, M. Lila n, I. Raskin*

author keywords: Dietary anthocyanins; Metabolic syndrome; Glucose metabolism; Maqui Berry
TL;DR: It is observed that oral administration of ANC improved fasting blood glucose levels and glucose tolerance in hyperglycaemic obese C57BL/6J mice fed a high fat diet and D3S5G also increased glucose uptake in L6 myotubes and is at least partially responsible for ANC's anti-diabetic properties. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 9, 2020

2012 journal article

Kinetic Study of Catechin Stability: Effects of pH, Concentration, and Temperature

Journal of Agricultural and Food Chemistry, 60(51), 12531–12539.

author keywords: EGCG; stability; pH; kinetic model; shelf life; tea
MeSH headings : Catechin / analogs & derivatives; Catechin / chemistry; Drug Stability; Food Preservation; Hydrogen-Ion Concentration; Kinetics; Solutions / chemistry; Tea / chemistry; Temperature
TL;DR: An empirical model for catechin content was established as a function of pH and temperature and showed good correlation between green tea concentrated solutions and previous reports of catechine stability in powder systems, providing useful approaches for shelf life calculations and catechchin loss predictions at given temperature and pH conditions in green tea concentrates. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2012 journal article

Does flavor impact function? Potential consequences of polyphenol–protein interactions in delivery and bioactivity of flavan-3-ols from foods

Physiology & Behavior, 107(4), 591–597.

author keywords: Polyphenols; Proteins; Astringency; Binding; Flavan-3-ols; Bioaccessibility; Bioavailability
MeSH headings : Astringents / metabolism; Biological Availability; Digestive System / drug effects; Digestive System / enzymology; Enzyme Inhibitors / pharmacokinetics; Enzyme Inhibitors / pharmacology; Flavonoids / chemistry; Flavonoids / pharmacokinetics; Flavonoids / pharmacology; Humans; Molecular Structure; Polyphenols / chemistry; Polyphenols / pharmacokinetics; Polyphenols / pharmacology; Protein Binding; Proteins / metabolism; Taste
TL;DR: The physiological implications of these interactions in food and through the gut will be discussed in relation to manipulation of flavan-3-ol bioavailability, metabolism and biological activities including inhibition of digestive enzymes in the gut. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Crossref
Added: August 28, 2020

2012 journal article

Effect of a flash vacuum expansion process on grape juice yield and quality

LWT - Food Science and Technology, 48(2), 147–155.

By: S. Paranjpe*, M. Ferruzzi* & M. Morgan*

author keywords: Flash vacuum expansion; Pectinase; Grape juice quality; Juice yield; Polyphenols
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Crossref
Added: August 28, 2020

2012 journal article

Quantification of anthocyanidins in the grapes and grape juice products with acid assisted hydrolysis using LC/MS

Journal of Functional Foods, 4(4), 710–717.

author keywords: Grape; LC-MS; Polyphenols; Anthocyanins; Anthocyanidins; Acidic hydrolysis
Source: Crossref
Added: August 28, 2020

2012 journal article

Enzymatic synthesis of substituted epicatechins for bioactivity studies in neurological disorders

Biochemical and Biophysical Research Communications, 417(1), 457–461.

By: J. Blount*, M. Ferruzzi*, D. Raftery*, G. Pasinetti* & R. Dixon*

author keywords: Alzheimer's disease; Grape seed extract; Polyphenols; Glucuronosyl transferase; Epicatechin glucuronides
MeSH headings : Alzheimer Disease / blood; Alzheimer Disease / metabolism; Animals; Catechin / analogs & derivatives; Catechin / biosynthesis; Catechin / chemistry; Catechin / isolation & purification; Chromatography, High Pressure Liquid; Glucuronates / biosynthesis; Glucuronates / chemistry; Glucuronates / isolation & purification; Glucuronosyltransferase / chemistry; Humans; Mice; Proanthocyanidins / biosynthesis; Proanthocyanidins / blood; Proanthocyanidins / chemistry; Recombinant Proteins / chemistry; UDP-Glucuronosyltransferase 1A9
TL;DR: These studies form a basis for generation of mg quantities of pure epicatechin (methyl) glucuronides of biological significance, and provide clarification of structure of previously identified epicateschin metabolites. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2012 journal article

Meal triacylglycerol profile modulates postprandial absorption of carotenoids in humans

Molecular Nutrition & Food Research, 56(6), 866–877.

By: S. Goltz*, W. Campbell*, C. Chitchumroonchokchai*, M. Failla* & M. Ferruzzi*

author keywords: Bioavailability; Carotenoids; Clinical trial; Dietary triacylglycerol; Postprandial absorption
MeSH headings : Adolescent; Adult; Butter; Carotenoids / administration & dosage; Carotenoids / blood; Carotenoids / metabolism; Cross-Over Studies; Diet, High-Fat; Fatty Acids, Monounsaturated / administration & dosage; Female; Humans; Intestinal Absorption; Lutein / administration & dosage; Lutein / blood; Lutein / metabolism; Male; Middle Aged; Nutritive Value; Postprandial Period; Rapeseed Oil; Soybean Oil / administration & dosage; Triglycerides / administration & dosage; Triglycerides / blood; Vegetables / chemistry; Young Adult
TL;DR: While both amount and source of co-consumed lipid affect carotenoid bioavailability from vegetables, amount appears to exert a stronger effect. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2012 journal article

Relative impact of flavonoid composition, dose and structure on vascular function: A systematic review of randomised controlled trials of flavonoid-rich food products

Molecular Nutrition & Food Research, 56(11), 1605–1616.

author keywords: Blood pressure; Cardiovascular disease; Dose response; Flavonoids; Flow-mediated dilation
MeSH headings : Biomarkers / metabolism; Blood Pressure / drug effects; Cardiovascular Diseases / diet therapy; Cardiovascular Diseases / drug therapy; Cardiovascular Diseases / metabolism; Catechin / pharmacology; Dose-Response Relationship, Drug; Endothelium, Vascular / drug effects; Endothelium, Vascular / physiology; Flavonoids / chemistry; Flavonoids / pharmacology; Flavonoids / therapeutic use; Humans; Proanthocyanidins / pharmacology; Randomized Controlled Trials as Topic; Regression Analysis; Structure-Activity Relationship; United States
TL;DR: The present analysis suggests that flavonoid bioactivity does not follow a classical linear dose-response association and this may have important biological implications. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Crossref
Added: March 8, 2020

2012 journal article

Promoting wellness in Alaskan villages: Integrating traditional knowledge and science of wild berries

Ecohealth, 8(2), 199–209.

By: C. Flint*, E. Robinson*, J. Kellogg n, G. Ferguson*, L. BouFajreldin*, M. Dolan*, I. Raskin*, M. Lila n

author keywords: traditional ecological knowledge; wild berries; environmental change; participatory research; youth; health; community wellness
MeSH headings : Alaska; Alcoholism / ethnology; Analysis of Variance; Climate Change; Community-Based Participatory Research; Environmental Pollution / adverse effects; Ethnobotany / methods; Feeding Behavior / ethnology; Focus Groups; Fruit / chemistry; Fruit / physiology; Health Knowledge, Attitudes, Practice / ethnology; Health Promotion / methods; Humans; Indians, North American; Interviews as Topic; Inuit; Social Behavior
TL;DR: Multiple berry species were found to have powerful bioactive health properties for ameliorating metabolic syndrome as well as importance for community wellness and suggest the importance of incorporating locally available foods and socio-cultural traditions into community wellness programming. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Source: NC State University Libraries
Added: February 17, 2020

2012 journal article

Flavonoid metabolism: the synthesis of phenolic glucuronides and sulfates as candidate metabolites for bioactivity studies of dietary flavonoids

Tetrahedron, 68(22), 4194–4201.

author keywords: Flavanoids; Metabolites; Phenolic glucuronides; Phenolic sulfates; Synthesis
TL;DR: The synthesis of a series of phenolic glucuronide 1a–e and sulfate 2a-e derivates as candidate metabolites for use as reference compounds in metabolic profiling studies and for the exploration of flavonoid bioactivity are detailed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020

2012 journal article

Vascular bioactivity of anthocyanins and phenolic acid degradants: modulation of superoxide and nitric oxide

Proceedings of the Nutrition Society, 71(OCE2).

By: M. Edwards*, C. Czank*, A. Cassidy* & C. Kay*

TL;DR: Investigation of vascular bioactivity of selected anthocyanins and phenolic degradants, and potential synergy between flavonoids and ascorbic acid found superoxide was significantly decreased by protocatechuic acid in combination with two Flavonoids, epicatechin and quercetin, and asCorbic Acid; although to a lesser extent than with protocatechaic acid alone. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020

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