Works Published in 2000
Displaying all 10 works
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2000 chapter
Air-liquid interface culture systems for exposure of differentiated cells to oxidant stress.
In Models and methods in cell signaling and gene expression applications to oxidative stress research. (pp. 15–30).
Source: NC State University Libraries
Added: August 6, 2018
2000 article
Response of human airway epithelium in vitro to inflammatory mediators - Dependence on the state of cellular differentiation
Martin, L. D., Norford, D., Voynow, J., & Adler, K. B. (2000, May). CHEST, Vol. 117, pp. 267S–267S.
TL;DR:
The data suggest that the response of the airway epithelium to inflammatory mediators may be markedly different in undifferentiated vs fully differentiated cells, and these responses may play a role in further exacerbation of airway inflammation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 article
Myristoylated alanine-rich C-kinase substrate protein: A major intracellular regulatory molecule controlling secretion of mucin by human airway goblet cells.
Chest, Vol. 117, pp. 266S–267S.
Source: NC State University Libraries
Added: August 6, 2018
2000 article
Mechanisms of human neutrophil elastase-induced mucin hypersecretion by human airway epithelial cells in vitro.
American Journal of Respiratory and Critical Care Medicine, Vol. 161, p. A155.
Source: NC State University Libraries
Added: August 6, 2018
2000 article
MARCKS protein: a key intracellular molecule controlling mucin secretion by human airway goblet cells.
American Journal of Respiratory and Critical Care Medicine, Vol. 161, p. A259.
Source: NC State University Libraries
Added: August 6, 2018
2000 article
Interaction of TGF? and EGF receptor mediates IL-13 induced mucous cell hyperplasia in human airway epithelium in vitro.
American Journal of Respiratory and Critical Care Medicine, Vol. 161, p. A779.
Source: NC State University Libraries
Added: August 6, 2018
2000 article
Induction of heparin-binding epidermal growth factor (HB-EGF) mRNA in normal human bronchial epithelial cells by metal-induced oxidative stress.
American Journal of Respiratory and Critical Care Medicine, Vol. 161, p. A149.
Source: NC State University Libraries
Added: August 6, 2018
2000 article
Differential generation of intracellular oxidants by TNF? and exogenous superoxide affords distinct expression of IL-6 in human airway epithelium in vitro.
American Journal of Respiratory and Critical Care Medicine, Vol. 161, p. A152.
Source: NC State University Libraries
Added: August 6, 2018
2000 journal article
Residual oil fly ash induces cytotoxicity and mucin secretion by guinea pig tracheal epithelial cells via an oxidant-mediated mechanism
TOXICOLOGY AND APPLIED PHARMACOLOGY, 163(3), 221–230.
author keywords: mucin; cytotoxicity; residual oil fly ash; oxidant
MeSH headings : Animals; Antioxidants / pharmacology; Carbon / toxicity; Cell Survival / drug effects; Cells, Cultured; Coal Ash; Dust / adverse effects; Epithelial Cells / drug effects; Gene Expression / drug effects; Guinea Pigs; Industrial Waste; Metals / toxicity; Mucins / biosynthesis; Mucins / genetics; Mucins / metabolism; Oxidants / pharmacology; Particulate Matter; RNA, Messenger / biosynthesis; RNA, Messenger / genetics; Trachea / cytology; Trachea / drug effects; Trachea / metabolism
TL;DR:
ROFA enhances mucin secretion and generates toxicity in vitro to airway epithelium via a mechanism(s) involving generation of oxidant stress, perhaps related to depletion of cellular antioxidant capacity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Effects of TNF-alpha on expression of ICAM-1 in human airway epithelial cells in vitro - Signaling pathways controlling surface and gene expression
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 22(6), 685–692.
MeSH headings : Antibodies, Monoclonal; Bronchi / cytology; Cell Line; Epithelial Cells / enzymology; Epithelial Cells / immunology; Flow Cytometry; Gene Expression / immunology; Humans; In Vitro Techniques; Intercellular Adhesion Molecule-1 / genetics; Intercellular Adhesion Molecule-1 / immunology; L-Lactate Dehydrogenase / metabolism; NF-kappa B / genetics; NF-kappa B / metabolism; Promoter Regions, Genetic / physiology; RNA Processing, Post-Transcriptional / physiology; RNA, Messenger / genetics; RNA, Messenger / metabolism; Respiratory Mucosa / cytology; Signal Transduction / immunology; Tumor Necrosis Factor-alpha / pharmacology
TL;DR:
The intracellular signaling pathway leading to enhanced expression appeared to involve activation of a phospholipase C that hydrolyzes phosphatidylcholine (PC-PLC) becaus...
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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