Works Published in 2001
Displaying all 11 works
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2001 chapter
MARCKS protein: a potential modulator of airway mucin secretion.
In Cilia and mucus: from development to respiratory disease. (pp. 179–193).
Source: NC State University Libraries
Added: August 6, 2018
2001 chapter
Interleukin-13 induced mucous cell hyperplasia in airway epithelium.
In Cilia and mucus: from development to respiratory disease. (pp. 253–263).
Source: NC State University Libraries
Added: August 6, 2018
2001 article
MARCKS protein interaction with the cellular contractile machinery may regulate mucin secretion by human airway epithelium.
American Journal of Respiratory and Critical Care Medicine, Vol. 163, p. A225.
Source: NC State University Libraries
Added: August 6, 2018
2001 article
Differentiation of murine tracheal epithelial cells in vitro.
American Journal of Respiratory and Critical Care Medicine, Vol. 163, p. A225.
Source: NC State University Libraries
Added: August 6, 2018
2001 article
Autocrine production of TGFa mediates interleukin 13-induced proliferation of human airway epithelial cells during development of a mucous phenotype in vitro.
American Journal of Respiratory and Critical Care Medicine, Vol. 163, p. A738.
Source: NC State University Libraries
Added: August 6, 2018
2001 journal article
Interleukin-13 induces proliferation of human airway epithelial cells in vitro via a mechanism mediated by transforming growth factor-alpha
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 25(6), 739–743.
MeSH headings : Bronchi / cytology; Bronchi / drug effects; Cell Division / drug effects; Cells, Cultured / cytology; Cells, Cultured / drug effects; Enzyme Inhibitors / pharmacology; Epithelial Cells / cytology; Epithelial Cells / drug effects; Epithelial Cells / metabolism; ErbB Receptors / antagonists & inhibitors; ErbB Receptors / physiology; Humans; Interleukin-13 / pharmacology; Models, Biological; Quinazolines; Signal Transduction / drug effects; Signal Transduction / physiology; Transforming Growth Factor alpha / antagonists & inhibitors; Transforming Growth Factor alpha / immunology; Transforming Growth Factor alpha / metabolism; Tyrphostins / pharmacology
TL;DR:
This study provides the first experimental evidence that IL-13 can initiate a proliferative response of human airway epithelium in the absence of inflammatory cells or other cell types.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2001 article
Interleukin-13, a mediator of subepithelial fibrosis, enhances growth factor production and proliferation in human airway epithelial cells
Booth, B., Bonner, J., Akley, N., Macchione, M., Adler, K., & Martin, L. D. (2001, July). CHEST, Vol. 120, pp. 15S–15S.
TL;DR:
Injured airways with regions of regenerating/differentiating cells and regions of normal fully differentiated cells have been mimicked by examining the effects of IL-13 on normal human bronchial epithelial cells during mucociliary differentiation in air/liquid interface culture.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2001 journal article
Enhanced expression of mucin genes in a guinea pig model of allergic asthma
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 25(5), 644–651.
MeSH headings : Amino Acid Sequence; Animals; Antineoplastic Agents / pharmacology; Asthma / physiopathology; Base Sequence; Bronchial Hyperreactivity / physiopathology; Cells, Cultured; Chemokine CCL11; Chemokines, CC / genetics; Cloning, Molecular; Conserved Sequence; Disease Models, Animal; Eosinophils / immunology; Gene Expression / physiology; Guinea Pigs; Histamine / pharmacology; Hypersensitivity / physiopathology; Inflammation Mediators / pharmacology; Molecular Sequence Data; Mucin 5AC; Mucin-2; Mucins / genetics; Ovalbumin / immunology; Ovalbumin / pharmacology; RNA, Messenger / analysis; Respiratory Mucosa / cytology; Respiratory Mucosa / physiology; Trachea / cytology; Tumor Necrosis Factor-alpha / pharmacology
TL;DR:
Results of these studies suggest that the OVA-sensitized guinea pig responds to allergic challenge with enhanced expression of genes that likely play a role in increased airway inflammation and mucin overproduction, and enhanced mucin gene expression appears to occur before eosinophil infiltration.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2001 journal article
Encapsulation, permeability, and cellular uptake characteristics of hollow nanometer-sized conductive polymer capsules
JOURNAL OF PHYSICAL CHEMISTRY B, 105(37), 8872–8876.
Source: Web Of Science
Added: August 6, 2018
2001 journal article
Vanadium stimulates human bronchial epithelial cells to produce heparin-binding epidermal growth factor-like growth factor - A mitogen for lung fibroblasts
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 24(2), 123–131.
MeSH headings : Blotting, Northern; Blotting, Western; Bronchi / drug effects; Bronchi / metabolism; Cells, Cultured; DNA Primers / chemistry; Enzyme Inhibitors / pharmacology; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor / biosynthesis; Epidermal Growth Factor / genetics; Epithelial Cells / drug effects; Epithelial Cells / metabolism; ErbB Receptors / antagonists & inhibitors; Fibroblast Growth Factor 2 / metabolism; Fibroblasts / drug effects; Heparin-binding EGF-like Growth Factor; Humans; Immunoenzyme Techniques; Intercellular Signaling Peptides and Proteins; Lung / physiology; Mitogen-Activated Protein Kinase Kinases / antagonists & inhibitors; Mitogen-Activated Protein Kinases / antagonists & inhibitors; Protein Tyrosine Phosphatases / antagonists & inhibitors; RNA, Messenger / metabolism; Receptors, Platelet-Derived Growth Factor / antagonists & inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Vanadium / pharmacology; p38 Mitogen-Activated Protein Kinases
TL;DR:
It is reported that conditioned medium from normal human bronchial epithelial cells (NHBECs) contains mitogenic activity for human lung fibroblasts that is blocked by the epidermal growth factor receptor (EGF-R) tyrosine kinase inhibitor AG1478 and by neutralizing antibodies raised against heparin-binding epidermis growth factor-like growth factor (HB-EGF).
(via Semantic Scholar)
citeseerx.ist.psu.edu (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2001 journal article
MARCKS protein is a key molecule regulating mucin secretion by human airway epithelial cells in vitro
JOURNAL OF BIOLOGICAL CHEMISTRY, 276(44), 40982–40990.
MeSH headings : Actins / metabolism; Amino Acid Sequence; Cyclic GMP-Dependent Protein Kinases / metabolism; Cytoplasm / metabolism; Down-Regulation; Enzyme Activation; Epithelial Cells / enzymology; Epithelial Cells / metabolism; Exocytosis; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Molecular Sequence Data; Mucins / metabolism; Myosins / metabolism; Myristoylated Alanine-Rich C Kinase Substrate; Phosphorylation; Protein Kinase C / metabolism; Proteins / physiology; Trachea / cytology; Trachea / enzymology; Trachea / metabolism
TL;DR:
Several novel intracellular targets for pharmacological intervention in disorders involving aberrant secretion of respiratory mucin are suggested and may relate to other lesions involving exocytosis of membrane-bound granules in various cells and tissues.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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