Works Published in 2005

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Displaying all 14 works

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2005 journal article

Equine herpesvirus-1 infection induces IFN-γ production by equine T lymphocyte subsets

Veterinary Immunology and Immunopathology, 103(3-4), 207–215.

By: C. Breathnach*, G. Soboll*, M. Suresh* & D. Lunn*

author keywords: horses; EHV-1; intracellular staining; flow cytometry; interferon gamma
MeSH headings : Animals; Antibodies, Monoclonal / immunology; Flow Cytometry / veterinary; Herpesviridae Infections / immunology; Herpesviridae Infections / veterinary; Herpesviridae Infections / virology; Herpesvirus 1, Equid / immunology; Horse Diseases / immunology; Horse Diseases / virology; Horses; Interferon-gamma / biosynthesis; Interferon-gamma / immunology; Ionomycin / immunology; Lymphocyte Activation / immunology; Retrospective Studies; T-Lymphocyte Subsets / immunology; T-Lymphocyte Subsets / virology; T-Lymphocytes, Cytotoxic / immunology; Tetradecanoylphorbol Acetate / immunology
TL;DR: It is demonstrated that EHV-1 challenge infection of ponies results in increased production of IFN-γ by virus-specific T lymphocytes, and that this response can be quantitated using flow cytometry. (via Semantic Scholar)
Source: Crossref
Added: July 27, 2019

2005 journal article

Bartonella henselae and Rickettsia seroreactivity in a sick cat population from North Carolina

International Journal of Applied Research in Veterinary Medicine, 3(4), 287.

By: E. Breitschwerdt, J. Levine, S. Radulovic, S. Hanby, D. Kordick & K. Perle

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors

GENOME RESEARCH, 15(12), 1831–1837.

By: R. Thomas n, A. Scott n, C. Langford*, S. Fosmire*, C. Jubala*, T. Lorentzen*, C. Hitte*, E. Karlsson ...

MeSH headings : Animals; Cell Line, Tumor; Chromosomes, Artificial, Bacterial / genetics; Cloning, Molecular; Dogs; Genomic Library; In Situ Hybridization, Fluorescence; Nucleic Acid Hybridization / methods; Osteosarcoma / genetics; Osteosarcoma / pathology
TL;DR: Examples of the varied applications of the small-scale genomic microarray resource to tumor cytogenetics, in combination with other molecular cytogenetic techniques are provided. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

The dog as a sentinel for human infection: Prevalence of Borrelia burgdorferi C6 antibodies in dogs from southeastern and mid-Atlantic states

VECTOR-BORNE AND ZOONOTIC DISEASES, 5(2), 101–109.

author keywords: Borrelia burgdorferi C6; dogs; lyme disease
MeSH headings : Animals; Antibodies, Bacterial / blood; Arachnid Vectors / microbiology; Borrelia burgdorferi / immunology; Carrier State / veterinary; Disease Reservoirs / veterinary; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Enzyme-Linked Immunosorbent Assay / veterinary; Humans; Ixodes / microbiology; Lyme Disease / epidemiology; Lyme Disease / microbiology; Lyme Disease / transmission; Maryland / epidemiology; North Carolina / epidemiology; Pennsylvania / epidemiology; Sentinel Surveillance; Seroepidemiologic Studies; Virginia / epidemiology; Zoonoses
TL;DR: The hypothesis that B. burgdorferi transmission seems to occur infrequently in North Carolina dogs as compared to dogs residing in other southeastern and mid-Atlantic states is supported and the utility of dogs as a sentinel to characterize the risk of B. Burgdorferis transmission to humans in a defined geographical location is supported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

The effects of inhibiting cytochrome P450 3A, p-glycoprotein, and gastric acid secretion on the oral bioavailability of methadone in dogs

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 28(5), 461–466.

MeSH headings : ATP Binding Cassette Transporter, Subfamily B, Member 1 / drug effects; Administration, Oral; Animals; Area Under Curve; Biological Availability; Cross-Over Studies; Cytochrome P-450 CYP3A / drug effects; Cytochrome P-450 CYP3A Inhibitors; Dogs / metabolism; Enzyme Inhibitors / administration & dosage; Enzyme Inhibitors / pharmacology; Female; Gastric Acid / metabolism; Injections, Intravenous / veterinary; Ketoconazole / administration & dosage; Ketoconazole / pharmacology; Male; Methadone / administration & dosage; Methadone / blood; Methadone / pharmacokinetics; Omeprazole / administration & dosage; Omeprazole / pharmacology; Proton Pump Inhibitors
TL;DR: In contrast to its pharmacokinetics humans, methadone has a short elimination half-life, rapid clearance, and low oral bioavailability in dogs and the extent of absorption is not affected by inhibition of CYP3A, p-gp, and gastric acid secretion. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Pharmacokinetics and tissue fluid distribution of cephalexin in the horse after oral and i.v. administration

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 28(5), 425–431.

By: J. Davis, J. Salmon n & M. Papich*

MeSH headings : Administration, Oral; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Area Under Curve; Cephalexin / administration & dosage; Cephalexin / blood; Cephalexin / pharmacokinetics; Cross-Over Studies; Female; Horses / metabolism; Injections, Intravenous / veterinary; Male; Tissue Distribution
TL;DR: This study showed that cephalexin at a dose of 30 mg/kg administered orally at 8 h dosage intervals in horses can produce plasma and interstitial fluid drug concentrations that are in a range recommended to treat susceptible gram-positive bacteria (MIC < or = 0.5 microg/mL). (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Preferential and non-selective cyclooxygenase inhibitors reduce inflammation during lipopolysaccharide-induced synovitis

RESEARCH IN VETERINARY SCIENCE, 78(2), 189–192.

By: A. Morton n, N. Campbell n, F. Gayle n, W. Redding n & A. Blikslager n

author keywords: prostaglandin; synovitis; etodolac; phenylbutazone; thromboxane
MeSH headings : Animals; Anti-Inflammatory Agents / pharmacology; Cyclooxygenase Inhibitors / pharmacology; Dinoprostone / analysis; Enzyme-Linked Immunosorbent Assay / veterinary; Etodolac / pharmacology; Horse Diseases / drug therapy; Horse Diseases / enzymology; Horse Diseases / pathology; Horses; Leukocyte Count / veterinary; Lipopolysaccharides; Phenylbutazone / pharmacology; Random Allocation; Synovial Fluid / chemistry; Synovitis / drug therapy; Synovitis / enzymology; Synovitis / pathology; Synovitis / veterinary; T-Box Domain Proteins / analysis
TL;DR: Etodolac may serve as a more selective anti-inflammatory agent than phenylbutazone for treatment of equine synovitis, as compared to non-selective COX inhibitors. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Microarray data analysis of mouse neoplasia

TOXICOLOGIC PATHOLOGY, 33(1), 127–135.

By: D. Malarkey, J. Parker, C. Turman n, A. Scott n, R. Paules*, J. Collins*, R. Maronpot*

author keywords: liver; lung; mammary gland; rodent; microarray gene expression analysis; genomics; cancer; review; gene expression profiling; neoplasia
MeSH headings : Animals; Humans; Microarray Analysis; Neoplasms / etiology; Neoplasms / genetics; Neoplasms / pathology
TL;DR: It is clear that pathologists and toxicologists, in collaboration with molecular biologists, bioinformatists, and other scientists are making great strides in the design, analysis, and interpretation of microarray data for cancer studies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2005 article

Pharmacokinetics and tissue distribution of itraconazole after oral and intravenous administration to horses

Davis, J. L., Salmon, J. H., & Papich, M. G. (2005, October). AMERICAN JOURNAL OF VETERINARY RESEARCH, Vol. 66, pp. 1694–1701.

By: J. Davis n, J. Salmon* & M. Papich*

MeSH headings : Administration, Oral; Animals; Antifungal Agents / administration & dosage; Antifungal Agents / pharmacokinetics; Chromatography, High Pressure Liquid / veterinary; Horses / metabolism; Injections, Intravenous / veterinary; Itraconazole / administration & dosage; Itraconazole / blood; Itraconazole / pharmacokinetics; Protein Binding
TL;DR: Itraconazole administered orally as a solution had higher, more consistent absorption than orally administered capsules and attained plasma concentrations that are inhibitory against fungi that infect horses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Novel chemically modified liquid medium that will support the growth of seven Bartonella species

Journal of Clinical Microbiology, 43(6), 2651–2655.

By: R. Maggi n, A. Duncan n & E. Breitschwerdt n

MeSH headings : Angiomatosis, Bacillary / microbiology; Animals; Bacteriological Techniques; Bartonella / classification; Bartonella / growth & development; Bartonella / isolation & purification; Bartonella henselae / growth & development; Bartonella henselae / isolation & purification; Blood / microbiology; Cat Diseases / microbiology; Cats; Colony Count, Microbial; Culture Media / chemistry; Humans
TL;DR: A novel, chemically modified, insect-based liquid culture medium is described that supports the growth of at least seven Bartonella species and may provide an advantage over conventional direct blood agar plating for the diagnostic confirmation of bartonellosis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Immune-mediated keratitis in horses: 19 cases (1998-2004)

VETERINARY OPHTHALMOLOGY, 8(4), 233–239.

By: B. Gilger n, T. Michau n & J. Salmon n

author keywords: cornea; equine; immune-mediated diseases; keratitis
MeSH headings : Animals; Cyclosporine / administration & dosage; Dexamethasone / administration & dosage; Female; Horse Diseases / epidemiology; Horse Diseases / etiology; Horse Diseases / pathology; Horse Diseases / therapy; Horses; Immunosuppressive Agents / administration & dosage; Keratitis / epidemiology; Keratitis / veterinary; Male; North Carolina / epidemiology; Ophthalmic Solutions / administration & dosage; Ophthalmologic Surgical Procedures / veterinary; Records / veterinary; Retrospective Studies; Severity of Illness Index
TL;DR: Clinical and histologic findings, treatment, and outcome of horses with suspected immune-mediated keratitis (IMMK) are described, with horses with superficial IMMK responding to topical medical therapy, but responded best to surgical removal of the lesion. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

The effects of patient positioning and slice selection on canine acetabular angle assessment with computed tomography

VETERINARY RADIOLOGY & ULTRASOUND, 46(1), 39–43.

By: S. Wang n, K. Mathews, I. Robertson n, M. Stebbins* & B. Trumpatori*

author keywords: acetabular; angle; canine; computed tomography; pelvic tilt; slice
MeSH headings : Acetabulum / anatomy & histology; Acetabulum / diagnostic imaging; Animals; Dogs / anatomy & histology; Pelvis / anatomy & histology; Pelvis / diagnostic imaging; Posture; Reference Values; Tomography, X-Ray Computed / veterinary
TL;DR: Significant variation in AAs with small differences in pelvic tilt and slice selection is found, and the floor of the sacral vertebral canal may be a reasonable landmark for this purpose and deserves further study. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Anesthetic effects of progesterone are undiminished in progesterone receptor knockout mice

BRAIN RESEARCH, 1033(1), 96–101.

By: D. Reddy n & L. Apanites n

author keywords: progesterone; neurosteroid; allopregnanolone; progesterone receptor; sleep; righting reflex
MeSH headings : Analysis of Variance; Anesthetics / blood; Anesthetics / pharmacology; Animals; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors / pharmacology; Female; Finasteride / pharmacology; Mice; Mice, Inbred C57BL; Mice, Knockout; Pregnanolone / blood; Pregnanolone / pharmacology; Progesterone / pharmacology; Reaction Time / drug effects; Receptors, Progesterone / deficiency; Receptors, Progesterone / genetics; Reflex / drug effects
TL;DR: The neurosteroid allopregnanolone partially mediates the anesthetic activity of progesterone by potentiation of GABA(A) receptor function, but this activity is not mediated by its interaction with PRs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Purification of a novel arthropod defensin from the American oyster, Crassostrea virginica

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 338(4), 1998–2004.

By: J. Seo n, J. Crawford*, K. Stone* & E. Noga n

author keywords: innate immunity; antibacterial peptide; arthropod defensin; American oyster; Crassostrea virginica
MeSH headings : Amino Acid Sequence; Animals; Anti-Infective Agents / chemistry; Anti-Infective Agents / isolation & purification; Chromatography, High Pressure Liquid / methods; Crassostrea / chemistry; Defensins / chemistry; Defensins / isolation & purification; Electrophoresis, Polyacrylamide Gel; Molecular Sequence Data; Sequence Alignment; Spectrometry, Mass, Electrospray Ionization
TL;DR: This is the first antimicrobial peptide to be isolated from any oyster species and it is named American oyster defensin (AOD), which had high sequence homology to arthropod defensins, including those from other bivalves, the mussels MyTilus edulis and Mytilus galloprovincialis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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