Works Published in 2009

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Displaying works 1 - 20 of 24 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2009 thesis

Evolution on an interacting fitness landscape: The effects of the interplay of epistasis and recombination on genetic structure

University of California, Santa Barbara.

By: B. Callahan

Source: ORCID
Added: August 21, 2019

2009 chapter

The Equine Immune System

In S. Reed, W. Bayly, D. Sellon, & W. B. Saunders (Eds.), Equine Internal Medicine (3rd ed., pp. 2–56).

By: D. Lunn & D. Horohov

Ed(s): S. Reed, W. Bayly, D. Sellon & W. Saunders

Source: NC State University Libraries
Added: August 4, 2019

2009 journal article

Sensitization of skin mast cells with IgE antibodies to Culicoides allergens occurs frequently in clinically healthy horses

Veterinary Immunology and Immunopathology, 132(1), 53–61.

By: B. Wagner*, W. Miller*, H. Erb*, D. Lunn* & D. Antczak*

author keywords: IgE; IgG; Allergy; Sensitization; Horse
MeSH headings : Aging; Allergens / immunology; Animals; Antibodies, Anti-Idiotypic / immunology; Basophils / immunology; Ceratopogonidae / immunology; Female; Histamine / blood; Horse Diseases / diagnosis; Horse Diseases / immunology; Horses; Hypersensitivity / diagnosis; Hypersensitivity / immunology; Hypersensitivity / veterinary; Immunization; Immunoglobulin E / immunology; Immunoglobulin G / immunology; Insect Proteins / immunology; Intradermal Tests; Male; Mast Cells / immunology; Skin / immunology
TL;DR: IgE was the major immunoglobulin involved in the sensitization of mast cells and basophils in horses at various ages and results are useful to diagnose Culicoides-induced allergy only in horses with allergic conditions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: August 4, 2019

2009 journal article

Emergent gene order in a model of modular polyketide synthases

Proceedings of the National Academy of Sciences, 106(46), 19410–19415.

author keywords: polyketides; horizontal transfer; evolution; collinearity; evolvability
MeSH headings : Animals; Bacteria / enzymology; Bacteria / genetics; Computer Simulation; Evolution, Molecular; Gene Order; Macrolides / metabolism; Models, Genetic; Plants / enzymology; Plants / genetics; Polyketide Synthases / biosynthesis; Polyketide Synthases / genetics; Protein Biosynthesis / genetics; Selection, Genetic
TL;DR: This work proposes an evolutionary origin for collinearity and demonstrates the mechanism by using a computational model of PKS evolution in a population, and provides a mathematical framework describing the secondary selection mechanism, which generalizes beyond the context of the present model. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: July 28, 2019

2009 journal article

The role of leukocyte biology in laminitis

Veterinary Immunology and Immunopathology, 129(3-4), 158–160.

author keywords: Laminitis; Horse; Leukocyte; Inflammation
MeSH headings : Animals; Foot Diseases / immunology; Foot Diseases / pathology; Foot Diseases / veterinary; Hoof and Claw; Horse Diseases / immunology; Horse Diseases / pathology; Horses; Inflammation / immunology; Inflammation / pathology; Inflammation / veterinary; Leukocytes / cytology; Leukocytes / immunology
TL;DR: The role of leukocytes in the initiation of laminitis, or as an intermediary factor, is currently being investigated using a limited array of models, and future studies require both new reagent and model systems if to clearly define how leukocyte propagate this disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2009 journal article

Equine Herpesvirus-1 Consensus Statement

Journal of Veterinary Internal Medicine, 23(3), 450–461.

By: D. Lunn*, N. Davis-Poynter*, M. Flaminio*, D. Horohov*, K. Osterrieder*, N. Pusterla*, H. Townsend*

author keywords: Abortion; Horse; Immunology; Infectious diseases; Myeloencephalopathy; Respiratory tract; Viral
MeSH headings : Animals; Central Nervous System Diseases / veterinary; Central Nervous System Diseases / virology; Disease Outbreaks / prevention & control; Disease Outbreaks / veterinary; Female; Herpesviridae Infections / epidemiology; Herpesviridae Infections / prevention & control; Herpesviridae Infections / veterinary; Herpesvirus 1, Equid / classification; Herpesvirus 1, Equid / physiology; Horse Diseases / epidemiology; Horse Diseases / virology; Horses; Pregnancy; Pregnancy Complications, Infectious / veterinary; Pregnancy Complications, Infectious / virology; Risk Factors; Viral Vaccines / immunology
TL;DR: This consensus statement draws together current knowledge in the areas of pathogenesis, strain variation, epidemiology, diagnostic testing, vaccination, outbreak prevention and control, and treatment of herpesvirus-1. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2009 journal article

Comparison of Four Methods to Quantify Equid Herpesvirus 1 Load by Real-Time Polymerase Chain Reaction in Nasal Secretions of Experimentally and Naturally Infected Horses

Journal of Veterinary Diagnostic Investigation, 21(6), 836–840.

By: N. Pusterla*, S. Hussey*, S. Mapes*, C. Leutenegger*, J. Madigan*, G. Ferraro*, W. Wilson*, D. Lunn*

author keywords: Equid herpesvirus 1; horses; nasal secretions; real-time polymerase chain reaction; viral load quantitation methods
MeSH headings : Animals; Herpesviridae Infections / diagnosis; Herpesviridae Infections / genetics; Herpesviridae Infections / veterinary; Herpesvirus 1, Equid / genetics; Herpesvirus 1, Equid / isolation & purification; Horse Diseases / diagnosis; Horse Diseases / genetics; Horse Diseases / virology; Horses; Male; Nasal Mucosa / virology; Nose / virology; Orchiectomy / veterinary; Polymerase Chain Reaction / methods; RNA, Viral / blood; Viral Load / veterinary
TL;DR: Comparisons of 4 methods to quantify Equid herpesvirus 1 (EHV-1) by real-time polymerase chain reaction (PCR) in nasal secretions from experimentally and naturally infected horses showed that all 4 calculation methods yielded comparable results, and that the different methods were significantly correlated with each other. (via Semantic Scholar)
Source: Crossref
Added: July 27, 2019

2009 journal article

Morphogenesis of the Primitive Gut Tube Is Generated by Rho/ROCK/Myosin II-Mediated Endoderm Rearrangements

DEVELOPMENTAL DYNAMICS, 238(12), 3111–3125.

By: R. Reed n, M. Womble n, M. Dush n, R. Tull n, S. Bloom n, A. Morckel n, E. Devlin*, N. Nascone-Yoder n

author keywords: gut; Xenopus; morphogenesis; endoderm, intercalation; elongation
MeSH headings : Animals; Animals, Genetically Modified; Body Patterning / genetics; Cell Polarity / genetics; Cell Shape / genetics; Embryo, Nonmammalian; Endoderm / cytology; Endoderm / embryology; Endoderm / metabolism; Gastrointestinal Diseases / congenital; Gastrointestinal Diseases / embryology; Gastrointestinal Tract / abnormalities; Gastrointestinal Tract / embryology; Gastrula / embryology; Gastrula / metabolism; Models, Biological; Morphogenesis / genetics; Nonmuscle Myosin Type IIB / genetics; Nonmuscle Myosin Type IIB / metabolism; Nonmuscle Myosin Type IIB / physiology; Signal Transduction / genetics; Xenopus / embryology; Xenopus / genetics; Xenopus / metabolism; rho-Associated Kinases / genetics; rho-Associated Kinases / metabolism; rho-Associated Kinases / physiology; rhoA GTP-Binding Protein / genetics; rhoA GTP-Binding Protein / metabolism; rhoA GTP-Binding Protein / physiology
TL;DR: The results suggest that the cellular and molecular events driving tissue elongation in the PGT are mechanistically analogous to those that function during gastrulation, but occur within a novel cylindrical geometry to generate an epithelial‐lined tube. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2009 journal article

An Animated Model of Reticulorumen Motility

JOURNAL OF VETERINARY MEDICAL EDUCATION, 36(4), 444–450.

author keywords: animated model; eructation; reticulorumen motility; rumination; student preference
MeSH headings : Animals; Attitude of Health Personnel; Computer Simulation; Computer-Assisted Instruction / methods; Education, Veterinary / methods; Educational Measurement; Gastrointestinal Motility / physiology; Humans; Models, Biological; Reticulum / physiology; Rumen / physiology; Ruminants / anatomy & histology; Ruminants / physiology; Students / psychology
TL;DR: An animated model of reticulorumen motility was developed and hypothesized that veterinary students would prefer use of the model over traditional instructional methods and would recommend the model to other veterinary students. (via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 article

Water-flow variation and pharmacoepidemiology of tetracycline hydrochloride administration via drinking water in swine finishing farms

Dorr, P. M., Nemechek, M. S., Scheidt, A. B., Baynes, R. E., Gebreyes, W. A., & Almond, G. W. (2009, August 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 235, pp. 299–304.

By: P. Dorr, M. Nemechek*, A. Scheidt, R. Baynes*, W. Gebreyes & G. Almond*

MeSH headings : Animal Husbandry / instrumentation; Animal Husbandry / methods; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Chromatography, High Pressure Liquid / veterinary; Cohort Studies; Cross-Sectional Studies; Drinking / physiology; Drinking Behavior; Swine / blood; Swine / physiology; Tetracycline / administration & dosage; Tetracycline / blood; Water / chemistry
TL;DR: Medication of pigs with tetracycline through water as performed in this study had questionable therapeutic value and many factors affected drinker flow rates and therefore the amount of medication pigs might have received. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Eosinophilic esophagitis in a dog

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 235(1), 61–65.

By: M. Mazzei*, S. Bissett*, K. Murphy, S. Hunter* & J. Neel*

MeSH headings : Animals; Anti-Inflammatory Agents / therapeutic use; Dog Diseases / pathology; Dogs; Eosinophilia / diagnosis; Eosinophilia / therapy; Eosinophilia / veterinary; Esophagitis / diagnosis; Esophagitis / pathology; Esophagitis / therapy; Esophagitis / veterinary; Female; Gastrointestinal Agents / therapeutic use; Prednisone / therapeutic use
TL;DR: The first description of eosinophilic esophagitis (EE) in a dog with a history of allergic skin disease is reported, highlighting the need to consider EE as a differential diagnosis for esphagitis and esophageal strictures in dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Effect of nonsteroidal anti-inflammatory drugs with varied cyclooxygenase-2 selectivity on cyclooxygenase protein and prostanoid concentrations in pyloric and duodenal mucosa of dogs

AMERICAN JOURNAL OF VETERINARY RESEARCH, 70(10), 1243–1249.

MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / pharmacology; Dogs; Drug Administration Schedule; Female; Gastric Mucosa / drug effects; Gastric Mucosa / metabolism; Gene Expression Regulation / drug effects; Male; Prostaglandin-Endoperoxide Synthases / metabolism; Prostaglandins / metabolism
TL;DR: It is suggested that, for these experimental conditions, there were no differences among the preferential and selective COX-2 inhibitors with regard to adverse effects on the gastric and duodenal portions of the gastrointestinal tract of dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Anti-inflammatory effects of intravenously administered lidocaine hydrochloride on ischemia-injured jejunum in horses

AMERICAN JOURNAL OF VETERINARY RESEARCH, 70(10), 1259–1268.

MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / adverse effects; Clonixin / adverse effects; Clonixin / analogs & derivatives; Female; Gene Expression Regulation, Enzymologic / drug effects; Horse Diseases / chemically induced; Horse Diseases / drug therapy; Horses; Intestinal Diseases / chemically induced; Intestinal Diseases / veterinary; Ischemia / chemically induced; Jejunum / drug effects; Lidocaine / therapeutic use; Male; Prostaglandin-Endoperoxide Synthases / genetics; Prostaglandin-Endoperoxide Synthases / metabolism
TL;DR: In horses with ischemia-injured jejunum, lidocaine administered IV reduced plasma prostaglandin E(2) metabolite concentration and mucosal COX-2 expression and coadministration of lidocane with flunixin ameliorated the flunxin-induced increase in mucosal neutrophil counts. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

p38 mitogen-activated kinase (MAPK) is essential for equine neutrophil migration

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 129(3-4), 181–191.

author keywords: Other animals; Inflammation; Laminitis
MeSH headings : Animals; CD18 Antigens / metabolism; Cell Adhesion; Cells, Cultured; Chemotaxis, Leukocyte / physiology; Dose-Response Relationship, Drug; Enzyme Inhibitors / pharmacology; Gene Expression Regulation / physiology; Horses / physiology; Imidazoles / pharmacology; Inflammation / metabolism; Leukotriene B4 / metabolism; Neutrophils / metabolism; Pyridines / pharmacology; p38 Mitogen-Activated Protein Kinases / antagonists & inhibitors; p38 Mitogen-Activated Protein Kinases / metabolism
TL;DR: Findings support a function for p38 MAPK in equine neutrophil migration and suggest the potential for the ability of p38MAPK inhibition to limit neutrophilic inflammation in the laminae during acute laminitis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Terameprocol, a methylated derivative of nordihydroguaiaretic acid, inhibits production of prostaglandins and several key inflammatory cytokines and chemokines

JOURNAL OF INFLAMMATION-LONDON, 6.

By: D. Eads n, R. Hansen n, A. Oyegunwa n, C. Cecil n, C. Culver n, F. Scholle n, I. Petty n, S. Laster n

TL;DR: TMP inhibited the LPS-induced production of lipid mediators and several key inflammatory cytokines and chemokines, both in vitro and in vivo, raising the possibility that TMP might be useful as a treatment for a variety of inflammatory disorders. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Role of p38 MAPK in LPS induced pro-inflammatory cytokine and chemokine gene expression in equine leukocytes

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 129(3-4), 192–199.

author keywords: Endotoxemia; LPS; p38 MAPK; Equine; Leukocytes; Inflammation
MeSH headings : Animals; Cells, Cultured; Chemokines / genetics; Chemokines / metabolism; Cytokines / genetics; Cytokines / metabolism; Gene Expression Regulation / physiology; Horses / blood; Horses / immunology; Horses / metabolism; Leukocytes / drug effects; Leukocytes / metabolism; Lipopolysaccharides / pharmacology; RNA, Messenger / metabolism; Signal Transduction / drug effects; Signal Transduction / physiology; p38 Mitogen-Activated Protein Kinases / metabolism
TL;DR: TNFalpha,IL-1beta, IL-6 and IL-8 are induced upon LPS stimulation of equine leukocytes and that this induction of gene expression is dependent on the p38 MAPK pathway, however, there are differences in the efficacy of the p 38 inhibitors tested here that may be explained by differences in specificity or potency. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Assessment of the Microbial Quality of Water Offered to Captive Psittacine Birds

JOURNAL OF AVIAN MEDICINE AND SURGERY, 23(1), 10–17.

author keywords: water quality; microbial; coliforms; heterotrophs; Pseudomonas; water; avian; Psittaciformes; psittacine birds
MeSH headings : Animal Husbandry; Animals; Animals, Domestic; Bacteria / classification; Bacteria / isolation & purification; Psittaciformes; Water Microbiology
TL;DR: Results suggest that potentially pathogenic bacteria can be found in water offered to companion psittacine birds, and additional studies are needed to assess whether these bacteria are clinically important causes of disease and to develop husbandry methods that will reduce contamination. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Assessment of clotrimazole gels for in vitro stability and in vivo retention in the frontal sinus of dogs

AMERICAN JOURNAL OF VETERINARY RESEARCH, 70(5), 640–647.

MeSH headings : Animals; Antifungal Agents / chemistry; Antifungal Agents / metabolism; Antifungal Agents / pharmacokinetics; Clotrimazole / chemistry; Clotrimazole / metabolism; Clotrimazole / pharmacokinetics; Dogs / metabolism; Drug Stability; Frontal Sinus / diagnostic imaging; Frontal Sinus / metabolism; Gels / chemistry; Gels / metabolism; Male; Poloxamer / chemistry; Poloxamer / metabolism; Tomography, X-Ray Computed / veterinary
TL;DR: Poloxamer gels had the most promise for improving drug contact within the frontal sinus of dogs, while limiting the inflammatory response. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2009 journal article

PCR detection of Bartonella bovis and Bartonella henselae in the blood of beef cattle

VETERINARY MICROBIOLOGY, 135(3-4), 308–312.

author keywords: Cattle; Bartonella bovis; Bartonella henselae; Co-infection; Bacteremia
MeSH headings : Angiomatosis, Bacillary / diagnosis; Angiomatosis, Bacillary / veterinary; Animals; Bacteremia / diagnosis; Bacteremia / veterinary; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Bartonella Infections / veterinary; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Cattle; Cattle Diseases / diagnosis; Cattle Diseases / microbiology; DNA Primers; DNA, Bacterial / genetics; DNA, Bacterial / isolation & purification; Introns; Meat / microbiology; North Carolina; Polymerase Chain Reaction / methods; RNA, Bacterial / genetics; RNA, Bacterial / isolation & purification; RNA, Ribosomal / genetics; RNA, Ribosomal / isolation & purification
TL;DR: This study describes the first detection of B. henselae in any large ruminant species in the world and supports the need for further investigation of prevalence and pathogenic potential of b. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 article

Carboxymethylcellulose and adhesion formation in horses reply

Veterinary Surgery, Vol. 38, pp. 429–429.

By: C. Fogle n

UN Sustainable Development Goal Categories
Sources: NC State University Libraries, ORCID
Added: August 6, 2018

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