Works Published in 2010

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Displaying works 1 - 20 of 27 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2010 journal article

Terminology Challenges: Defining Modified Release Dosage Forms in Veterinary Medicine

Journal of Pharmaceutical Sciences, 99(8), 3281–3290.

By: M. Martinez*, D. Lindquist* & S. Modric*

TL;DR: This manuscript reflects an initial effort to suggest definitions that may be appropriate for describing formulation effects in veterinary medicine. (via Semantic Scholar)
Source: ORCID
Added: February 1, 2024

2010 journal article

Evaluation of IgG concentration and IgG subisotypes in foals with complete or partial failure of passive transfer after administration of intravenous serum or plasma

Equine Veterinary Journal, 33(7), 681–686.

By: J. McClure*, J. DeLuca*, D. Lunn* & J. Miller*

author keywords: horse; foal; failure of passive transfer; transfusion; IgG subisotype; plasma; serum
MeSH headings : Animals; Animals, Newborn / blood; Animals, Newborn / immunology; Horse Diseases / immunology; Horses / blood; Horses / immunology; Immunity, Maternally-Acquired / immunology; Immunization, Passive / methods; Immunization, Passive / veterinary; Immunoglobulin G / administration & dosage; Immunoglobulin G / blood; Immunoglobulin Isotypes / administration & dosage; Immunoglobulin Isotypes / blood; Influenza Vaccines / administration & dosage; Injections, Intravenous / veterinary; Orthomyxoviridae Infections / immunology; Orthomyxoviridae Infections / veterinary; Tetanus / immunology; Tetanus / veterinary; Tetanus Toxoid / administration & dosage
TL;DR: The results of this study suggest that similar foal serum IgG concentrations can be achieved 3 days post-transfusion by administering 1 unit of plasma or 2-3 units of serum product. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: August 4, 2019

2010 journal article

Low-dose DNA vaccination into the submandibular lymph nodes in ponies

Veterinary Record, 167(8), 302–303.

By: G. Landolt*, S. Hussey*, K. Kreutzer*, A. Quintana* & D. Lunn*

MeSH headings : Animals; Cost-Benefit Analysis; Dose-Response Relationship, Immunologic; Hemagglutinin Glycoproteins, Influenza Virus / genetics; Hemagglutinin Glycoproteins, Influenza Virus / immunology; Horse Diseases / prevention & control; Horses; Immunotherapy / veterinary; Influenza A Virus, H3N8 Subtype / genetics; Influenza A Virus, H3N8 Subtype / immunology; Lymph Nodes; Orthomyxoviridae Infections / prevention & control; Pilot Projects; Random Allocation; Vaccination / methods; Vaccination / veterinary; Vaccines, DNA / administration & dosage; Vaccines, DNA / immunology
TL;DR: The ability to elicit an antigen-specific immune response in horses is desirable, either for protecting them against a pathogen, or for immunomodulation as a means of treating hypersensitivity diseases. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

Evidence for MHC class-l restricted cytotoxicity in the one-way, primary mixed lymphocyte reaction

Equine Veterinary Journal, 23(S12), 30–34.

By: M. O'Brien*, M. Holmes*, D. Lunn* & W. Duffus*

TL;DR: Allospecific cytotoxicity, demonstrated against Con A stimulated peripheral blood mononuclear cells (PBMC) in a 6 h chromium-release assay, was present from approximately 72 to 168 h of primary culture and peaked between 120 and 168 h. (via Semantic Scholar)
Source: Crossref
Added: July 27, 2019

2010 journal article

Haematological changes and equine lymphocyte subpopulation kinetics during primary infection and attempted re-infection of specific pathogen free foals with EHV-1

Equine Veterinary Journal, 23(S12), 35–40.

By: D. Lunn*, M. Holmes*, J. Gibson*, H. Field*, J. Kydd* & W. Duffus*

TL;DR: Four specific pathogen- (Equid Herpesvirus type 1 [EHV-1]) free foals aged 2 to 3 months were intranasally inoculated with 7 times 107 p.f.u. of EHV- 1, suggesting an effective immune response or subclinical infection. (via Semantic Scholar)
Source: Crossref
Added: July 27, 2019

2010 journal article

Pharyngeal lymphoid tissue: gatekeeper or showstopper?

Equine Veterinary Journal, 33(3), 218–220.

By: D. Lunn*

MeSH headings : Animals; Horses / immunology; Immunity, Mucosal; Lymphoid Tissue / physiology; Palatine Tonsil / immunology; Palatine Tonsil / physiology; Respiratory Mucosa / physiology
Source: Crossref
Added: July 27, 2019

2010 journal article

Passive transfer of maternal immunoglobulin isotype antibodies against tetanus and influenza and their effect on the response of foals to vaccination

Equine Veterinary Journal, 33(7), 644–650.

By: W. Wilson*, J. Mihalyi*, S. Hussey* & D. Lunn*

author keywords: horse; foals; vaccination; maternal antibodies; immunoglobulin; influenza; tetanus
MeSH headings : Adjuvants, Immunologic / administration & dosage; Animals; Animals, Newborn / immunology; Animals, Suckling / immunology; Antibodies, Bacterial / blood; Antibodies, Viral / blood; Colostrum / immunology; Female; Horse Diseases / immunology; Horse Diseases / microbiology; Horse Diseases / virology; Horses; Immunity, Maternally-Acquired; Immunoglobulin G / analysis; Immunoglobulin G / blood; Influenza Vaccines / administration & dosage; Influenza Vaccines / immunology; Orthomyxoviridae Infections / immunology; Orthomyxoviridae Infections / veterinary; Pregnancy; Tetanus / immunology; Tetanus / veterinary; Tetanus Toxoid / administration & dosage; Tetanus Toxoid / immunology; Time Factors; Vaccination / methods; Vaccination / veterinary; Vaccines, Inactivated / administration & dosage; Vaccines, Inactivated / immunology
TL;DR: Based on the finding that maternal antibodies exert a significant inhibitory effect on the response of foals to tetanus toxoid and inactivated influenza antigens, it is recommended that primary immunisation of foal born to vaccinated mares should not commence before age 6 months. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

A new modified live equine influenza virus vaccine: phenotypic stability, restricted spread and efficacy against heterologous virus challenge

Equine Veterinary Journal, 33(7), 630–636.

By: T. Chambers*, R. Holland*, L. Tudor*, H. Townsend*, A. Cook*, J. Bogdan*, D. Lunn*, S. Hussey* ...

author keywords: horse; intranasal; antigenic drift; backpassage; challenge; cold-adapted; modified-live virus
MeSH headings : Administration, Intranasal; Animals; Female; Horse Diseases / prevention & control; Horse Diseases / transmission; Horses; Influenza A virus / immunology; Influenza Vaccines / administration & dosage; Influenza Vaccines / immunology; Influenza Vaccines / standards; Male; Nebulizers and Vaporizers / veterinary; Orthomyxoviridae Infections / prevention & control; Orthomyxoviridae Infections / transmission; Orthomyxoviridae Infections / veterinary; Phenotype; Safety; Serial Passage; Time Factors; Treatment Outcome; Vaccination / veterinary; Vaccines, Attenuated / administration & dosage; Vaccines, Attenuated / immunology; Vaccines, Attenuated / standards; Virus Shedding
TL;DR: Results demonstrate that Flu Avert IN vaccine is safe and phenotypically stable, has low spontaneous transmissibility and is effective in protecting horses against challenge viruses representative of those in circulation worldwide. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

Onset of immunoglobulin production in foals

Equine Veterinary Journal, 35(6), 620–622.

By: D. Holznagel*, S. Hussey*, J. Mihalyi*, W. Wilson* & D. Lunn*

author keywords: horse; foal; IgG subclass; antibody; maternal antibody
MeSH headings : Animals; Animals, Newborn / blood; Animals, Newborn / immunology; Colostrum / immunology; Horses / blood; Horses / immunology; Immunity, Maternally-Acquired; Immunoglobulin A / biosynthesis; Immunoglobulin A / blood; Immunoglobulin G / biosynthesis; Immunoglobulin G / blood; Immunoglobulins / biosynthesis; Immunoglobulins / blood
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

Report of the Second Havemeyer EHV-1 Workshop, Steamboat Springs, Colorado, USA, September 2008

Equine Veterinary Journal, 42(6), 572–575.

By: J. Kydd*, J. Slater*, N. Osterrieder*, D. Antczak* & D. Lunn*

author keywords: horse; EHV-1; report; Havemeyer Foundation; equine herpesvirus myeloencephalopathy
MeSH headings : Animals; Colorado; Herpesviridae Infections / veterinary; Herpesvirus 1, Equid; Horse Diseases / epidemiology; Horse Diseases / virology; Horses
TL;DR: This report summarises the findings of the Second Havemeyer EHV-1 Workshop, which was held in Steamboat Springs, Colorado, USA in September 2008 and summarizes the key advances identified during and since the meeting. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

Control of EHV-1 viremia and nasal shedding by commercial vaccines

Vaccine, 28(32), 5203–5211.

By: L. Goehring*, B. Wagner*, R. Bigbie*, S. Hussey*, S. Rao*, P. Morley*, D. Lunn*

author keywords: EHV-1; Horses; Immunity; Vaccination
MeSH headings : Animals; Antibodies, Neutralizing / blood; Antibodies, Viral / blood; Antibody Formation; Female; Herpesviridae Infections / immunology; Herpesviridae Infections / prevention & control; Herpesviridae Infections / veterinary; Herpesvirus 1, Equid / immunology; Horse Diseases / immunology; Horse Diseases / prevention & control; Horses / immunology; Immunization Schedule; Neutralization Tests; Nose / immunology; Single-Blind Method; Viral Vaccines / immunology; Viremia / prevention & control; Viremia / veterinary; Virus Shedding
TL;DR: It is demonstrated that both commercial vaccines significantly suppressed EHV-1 disease and nasal viral shedding, and one vaccine suppressed days of viremia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

Onset and duration of immunity to equine influenza virus resulting from canarypox-vectored (ALVAC®) vaccination

Veterinary Immunology and Immunopathology, 135(1-2), 100–107.

By: G. Soboll*, S. Hussey*, J. Minke*, G. Landolt*, J. Hunter, S. Jagannatha*, D. Lunn*

author keywords: ALVAC (R)-influenza vaccination; Horse; Influenza virus
MeSH headings : Animals; Antibodies, Viral / blood; Antibody Formation / immunology; Canarypox virus; Horse Diseases / immunology; Horse Diseases / prevention & control; Horse Diseases / virology; Horses / immunology; Influenza A Virus, H3N8 Subtype / immunology; Influenza Vaccines / immunology; Influenza Vaccines / therapeutic use; Male; Orthomyxoviridae Infections / immunology; Orthomyxoviridae Infections / prevention & control; Orthomyxoviridae Infections / veterinary; Vaccines, Synthetic / immunology; Vaccines, Synthetic / therapeutic use; Virus Shedding / immunology
TL;DR: The results of this study clearly demonstrate the early onset, and 6-month duration of protective immunity resulting from ALVAC-influenza vaccination against challenge with American lineage equine influenza viruses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

Vaccination of ponies with the IE gene of EHV-1 in a recombinant modified live vaccinia vector protects against clinical and virological disease

Veterinary Immunology and Immunopathology, 135(1-2), 108–117.

By: G. Soboll*, C. Breathnach*, J. Kydd*, S. Hussey*, R. Mealey* & D. Lunn*

author keywords: EHV-1; Horses; Immediate early gene; Vaccination; IFN gamma
MeSH headings : Animals; Antibodies, Neutralizing / blood; Female; Genes, Immediate-Early / genetics; Genes, Immediate-Early / immunology; Genotype; Herpesviridae Infections / immunology; Herpesviridae Infections / prevention & control; Herpesviridae Infections / veterinary; Herpesvirus 1, Equid / genetics; Herpesvirus 1, Equid / immunology; Herpesvirus Vaccines / genetics; Herpesvirus Vaccines / immunology; Herpesvirus Vaccines / therapeutic use; Horse Diseases / immunology; Horse Diseases / prevention & control; Horses / immunology; Horses / virology; Interferon-gamma / blood; Male; Vaccines, Synthetic / genetics; Vaccines, Synthetic / immunology; Vaccines, Synthetic / therapeutic use; Vaccinia; Viremia / immunology; Viremia / veterinary
TL;DR: This is an important study showing that vaccination of ponies with the EHV-1 IE protein provides not only reduction in clinical disease but also reduction of cell associated viremia, which is a prerequisite for the prevention of abortion and neurological disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

Immune responses of Asian elephants (Elephas maximus) to commercial tetanus toxoid vaccine

Veterinary Immunology and Immunopathology, 133(2-4), 287–289.

By: W. Lindsay, E. Wiedner, R. Isaza*, H. Townsend*, M. Boleslawski* & D. Lunn*

author keywords: Asian elephant; Elephas maximus; Tetanus toxoid; Vaccination; Vaccine titer; Immunosenescence
MeSH headings : Age Factors; Animal Husbandry / methods; Animals; Animals, Zoo / immunology; Antibodies, Bacterial / biosynthesis; Antibodies, Bacterial / blood; Clostridium tetani / immunology; Elephants / immunology; Enzyme-Linked Immunosorbent Assay / veterinary; Female; Immunization Schedule; Immunization, Secondary / veterinary; Male; Species Specificity; Tetanus / immunology; Tetanus / prevention & control; Tetanus / veterinary; Tetanus Toxoid / administration & dosage; Time Factors
TL;DR: The great majority of elephants had titers prior to booster vaccination, and following revaccination all elephants demonstrated anamnestic increases in titers, indicating that this species does respond to tetanus vaccination. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

The Effect of Age on the Immune Response of Horses to Vaccination

Journal of Comparative Pathology, 142, S85–S90.

By: T. Muirhead*, J. McClure*, J. Wichtel*, H. Stryhn*, R. Markham*, D. McFarlane*, D. Lunn*

author keywords: geriatric; horse; immunosenescence; vaccination
MeSH headings : Age Factors; Aging / immunology; Animals; Horse Diseases / immunology; Horses / immunology; Immunization, Secondary; Immunologic Memory / immunology; Influenza A Virus, H3N8 Subtype / immunology; Influenza Vaccines / immunology; Orthomyxoviridae Infections / immunology; Rabies Vaccines / immunology; Vaccination / veterinary
TL;DR: Healthy aged horses mounted a primary immune response to rabies vaccine that was similar to that of younger adult horses, however, aged horses had a significantly reduced anamnestic response to influenza vaccination in comparison with the younger adult Horses, even though the pre-vaccination antibody titres of aged horses were higher. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

Molecular Investigation of the Viral Kinetics of Equine Herpesvirus-1 in Blood and Nasal Secretions of Horses after Corticosteroid-Induced Recrudescence of Latent Infection

Journal of Veterinary Internal Medicine, 24(5), 1153–1157.

By: N. Pusterla*, S. Hussey*, S. Mapes*, C. Johnson*, J. Collier*, J. Hill*, D. Lunn*, W. Wilson*

author keywords: EHV-1; Reactivation; Transmission
MeSH headings : Adrenal Cortex Hormones / pharmacology; Animals; Dexamethasone / pharmacology; Herpesvirus 1, Equid / physiology; Horse Diseases / blood; Horse Diseases / immunology; Horse Diseases / virology; Horses; Male; Mucus / virology; Time Factors; Virus Latency / drug effects; Virus Replication / physiology
TL;DR: EHV-1 was successfully reactivated after corticosteroid administration in latently infected horses, however, transmission of reactivated virus to sentinel horses was unsuccessful. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

American oyster, Crassostrea virginica, expresses a potent antibacterial histone H2B protein

Marine Biotechnology (New York, N.Y.), 12(5), 543–551.

By: J. Seo, J. Stephenson, J. Crawford, K. Stone & E. Noga

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

MR IMAGING FEATURES OF SURGICALLY INDUCED CORE LESIONS IN THE EQUINE SUPERFICIAL DIGITAL FLEXOR TENDON

VETERINARY RADIOLOGY & ULTRASOUND, 51(3), 280–287.

author keywords: core lesion; horse; MRI; tendon
MeSH headings : Animals; Forelimb / injuries; Horses / injuries; Magnetic Resonance Imaging / veterinary; Tendon Injuries / diagnosis; Tendon Injuries / veterinary; Tendons / pathology
TL;DR: The signal-difference-to-noise ratio decreased with the age of the lesion in all sequences in this study and through comparison between sequences, MR imaging may be able to provide information on various stages of tendon healing. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Development of a morphometric magnetic resonance image parameter suitable for distinguishing between normal dogs and dogs with cerebellar atrophy

Veterinary Radiology & Ultrasound, 51(3), 246–253.

By: R. Thames, I. Robertson, T. Flegel, D. Henke, D. O'Brien, J. Coates, N. Olby

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Comparison of an implantable telemetry device and an oscillometric monitor for measurement of blood pressure in anaesthetized and unrestrained green iguanas (Iguana iguana)

VETERINARY ANAESTHESIA AND ANALGESIA, 37(5), 434–439.

By: S. Chinnadurai n, R. DeVoe*, A. Koenig*, N. Gadsen*, A. Ardente n & S. Divers*

author keywords: anesthesia; arterial blood pressure; cardiovascular; Iguana iguana; oscillometric; telemetry
MeSH headings : Anesthesia / veterinary; Animals; Blood Pressure / physiology; Blood Pressure Determination / instrumentation; Blood Pressure Determination / methods; Blood Pressure Determination / veterinary; Blood Pressure Monitors / veterinary; Carotid Arteries / surgery; Female; Iguanas / physiology; Male; Oscillometry / instrumentation; Oscillometry / veterinary; Respiratory Rate / physiology; Telemetry / instrumentation; Telemetry / veterinary
TL;DR: The implantable transducer was a reliable means of determining blood pressure in this study, while the oscillometric device was unreliable and often failed to provide any reading. (via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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