Humans have basic needs for textiles and clothing. To satisfy human needs in varied contexts, a number of textile and garment companies have been formed. Huge work opportunities have been generated and they have also put the environment in danger by producing dangerous garbage. Chemicals and water are extensively used in the textile industry, particularly in the dyeing, printing, and finishing processes. These substances are regarded as harmful and cancerous. These substances damage the biological system by entering the environment through wastewater. Using biochemical engineering or live organisms to treat hazardous waste and stop environmental harm is a smart choice. The key advantages of using live creatures, such as enzymes, are that they can be used in benign environments with neutral or low acidity and medium or low temperatures. Additionally, the biological process' effluents do not degrade in the environment. This chapter focuses on the history, classification, makeup, and methods of usage of several enzymes in the chemical synthesis of materials for clothing. This chapter also covers the effect of biological processes on the environment.