2023 journal article

Plant Promoters and Terminators for High-Precision Bioengineering

BioDesign Research.

TL;DR: The function and features of plant core promoters, proximal and distal promoters, and terminators are reviewed, and their effects on and benchmarking strategies for regulating gene expression are reviewed. (via Semantic Scholar)
Source: ORCID
Added: July 8, 2023

High-precision bioengineering and synthetic biology require fine-tuning gene expression at both transcriptional and posttranscriptional levels. Gene transcription is tightly regulated by promoters and terminators. Promoters determine the timing, tissues and cells, and levels of the expression of genes. Terminators mediate transcription termination of genes and affect mRNA levels posttranscriptionally, e.g., the 3′-end processing, stability, translation efficiency, and nuclear to cytoplasmic export of mRNAs. The promoter and terminator combination affects gene expression. In the present article, we review the function and features of plant core promoters, proximal and distal promoters, and terminators, and their effects on and benchmarking strategies for regulating gene expression.