Machine learning reveals common transcriptomic signatures across rat brain and placenta following developmental organophosphate ester exposure
Newell, A. J., Jima, D., Reading, B., & Patisaul, H. B. (2023, July 3). TOXICOLOGICAL SCIENCES.
author keywords: artificial intelligence; toxicogenomics; neurodevelopment; OPFR; OPE; flame retardants; neurotoxicology; hippocampus; cortex; placenta
TL;DR:
It is shown how machine learning can complement more traditional analytical approaches to identify vulnerable "signature" pathways disrupted by chemical exposures and biomarkers of exposure.
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