2023 article
Lung nodule biopsy guided using a 30 MHz ultrasound transducer: in vitro study
HEALTH MONITORING OF STRUCTURAL AND BIOLOGICAL SYSTEMS XVII, Vol. 12488.
author keywords: High-frequency ultrasound; piezoelectric; ultrasound imaging; fine needle aspiration; imaging guided biopsy; lung nodule
TL;DR:
Results showed that the 30 MHz ultrasound transducer can map the geometry of the gelatin-foam boundary, indicating the capability of distinguishing tumor and healthy lung tissue with this ultrasound-guided biopsy technique.
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UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: July 31, 2023
Ultrasound is often favored in biopsy guidance since it is non-ionizing, inexpensive, portable, and has a high frame rate. However, imaging probes that operate at a low frequency may not be able to differentiate between tiny targets and surrounding tissues clearly, and at a high frequency, it suffers from tissue scattering and signals attenuation, which is hard to image deeper targets such as lung tissues. In this study, we developed a biopsy needle (with a size of 18 G) integrated with a 30 MHz high-frequency ultrasound transducer (axial resolution: ~ 100 µm) for the lung nodule biopsy in vitro test. To mimic contrasting biological tissues, a melamine foam-gelatin phantom was developed. With an advancing step of 0.5 mm, the distance from the biopsy needle to the gelatin-foam boundary was estimated by the speed of sound in gelatin and the time-of-flight of the echo signal. The results showed that the 30 MHz ultrasound transducer can map the geometry of the gelatin-foam boundary, indicating the capability of distinguishing tumor and healthy lung tissue with this ultrasound-guided biopsy technique.
