2023 article

No impact of polymorphism in the phosphodiesterase 5A gene in Cavalier King Charles Spaniels on pimobendan-induced inhibition of platelet aggregation response

Reimann, M. J., Faisst, D. N., Knold, M., Meurs, K. M., Stern, J. A., Cremer, S. E., … Olsen, L. H. (2023, September 24). JOURNAL OF VETERINARY INTERNAL MEDICINE.

By: M. Reimann *, D. Faisst*, M. Knold*, K. Meurs n , J. Stern*, S. Cremer *, J. Moller*, I. Ljungvall *, J. Haggstrom *, L. Olsen *

author keywords: dogs; genetic variation; heart disease; light transmission aggregometry; pharmacogenetics; platelet inhibition
TL;DR: Dogs with the PDE5A:E90K polymorphism did not appear to have altered platelet function or response to pimobendan treatment, and did not influence in vitro basal platelet aggregation response or the inhibitory effect of pimOBendan on platelets aggregation in CKCS. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: October 23, 2023

Abstract