2023 article

Telomere dysfunction in Tert knockout mice delays Braf<SUP>V600E</SUP>-induced melanoma development

Zhang, J., Zhang, F., Porter, K. I., Dakup, P. P., Wang, S., Robertson, G. P., … Zhu, J. (2023, September 20). INTERNATIONAL JOURNAL OF CANCER.

author keywords: BRAF; melanoma; mouse model; telomerase; telomere dysfunction
TL;DR: It is suggested that telomere dysfunction hampers melanomagenesis, and targeting telomeres crisis‐mediated genomic instability may hold promise for the prevention and treatment of melanoma. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: October 23, 2023

Abstract