2024 journal article

Improved detection in untargeted lipidomics through silver-doped infrared matrix-assisted laser desorption electrospray ionization

RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 38(15).

By: S. Eisenberg n & D. Muddiman n

UN Sustainable Development Goal Categories
Source: Web Of Science
Added: June 11, 2024

Silver doping of electrospray is known to increase the abundance of olefinic compounds detected by mass spectrometry. While demonstrated in targeted experiments, this has yet to be investigated in an untargeted study. Utilizing infrared matrix-assisted laser desorption electrospray ionization mass spectrometry imaging (IR-MALDESI-MSI), an untargeted lipidomics experiment on mouse liver was performed to evaluate the advantages of silver-doped electrospray.