2024 journal article

Bovine Rhinitis B Virus Variant as the Putative Cause of Bronchitis in Goat Kids

Viruses.

By: A. Noel *, J. Zhang *, H. Shen *, A. Saxena *, J. Groeltz-Thrush *, G. Li *, M. Rahe n 

Source: ORCID
Added: July 1, 2024

A diagnostic investigation into an outbreak of fatal respiratory disease among young goats in Iowa, USA revealed bronchitis lesions of unknown etiology and secondary bacterial bronchopneumonia. Hypothesis-free metagenomics identified a previously unreported picornavirus (USA/IA26017/2023), and further phylogenetic analysis classified USA/IA26017/2023 as an aphthovirus related to bovine rhinitis B virus. Viral nucleic acid was localized to lesions of bronchitis using in situ hybridization. This marks the first report of a picornavirus putatively causing respiratory disease in goats and highlights the potential for cross-species transmission of aphthoviruses.