2024 journal article

Cite it

Estimating rates of change to interpret quantitative wastewater surveillance of disease trends

SCIENCE OF THE TOTAL ENVIRONMENT, 951.

By: D. Holcomb ^*, A. Christensen ^*, K. Hoffman ^*, A. Lee ^*, A. Blackwood ^*, T. Clerkin ^*, J. Gallard-Gongora, A. Harris ⁿ  ...and 10 other authors, including 3 NC State authors, N. Kotlarz ⁿ , H. Mitasova ⁿ , S. Reckling ⁿ, F. de los Reyes III, J. Stewart ^*, V. Guidry ^*, R. Noble ^*, M. Serre ^*, T. Garcia^*, L. Engel ^*

author keywords: Wastewater-based epidemiology; Gaussian process derivatives; Simulation study; Generalized additive model; SARS-CoV-2; Time series analysis

10.1016/j.scitotenv.2024.175687

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open access via doi.org (repository)

UN Sustainable Development Goal Categories

6. Clean Water and Sanitation (OpenAlex)

Source: Web Of Science

Added: September 9, 2024

Wastewater monitoring data can be used to estimate disease trends to inform public health responses. One commonly estimated metric is the rate of change in pathogen quantity, which typically correlates with clinical surveillance in retrospective analyses. However, the accuracy of rate of change estimation approaches has not previously been evaluated.