Aflatoxin in maize and peanuts remains a critical problem in much of Africa and Asia. Many countries in these regions lack a systematic preharvest approach for providing government agencies with warnings of a potential threat to human and animal health resulting from excessive levels of aflatoxin in crops at harvest. This paper sets out an approach to such a system. It is based on the establishment of a surveillance system in each community to monitor aflatoxin contamination resulting from drought stress before harvest and advise on remedial actions. The system should be under the control of a central government coordinator. If severe drought stress occurs, the coordinator would arrange for samples of the affected crop to be provided to a central aflatoxin laboratory established and controlled by the relevant government department. Assays from the central laboratory would be sent via the central coordinator to a government scientific advisory body, which would recommend appropriate remedial action to be taken at government level.