2024 journal article

The biochemical effects of carotenoids in orange carrots on the colonic proteome in a mouse model of diet-induced obesity

FRONTIERS IN NUTRITION, 11.

By: E. Balbuena n, F. Milhem n, B. Kiremitci n, T. Williams n, L. Collins n, Q. Shu n, A. Eroglu n

author keywords: carotenoids; quantitative proteomics; colon; intestinal barrier; diet-induced obesity
Source: Web Of Science
Added: December 2, 2024

Carotenoids are naturally occurring pigments in plants and are responsible for the orange, yellow, and red color of fruits and vegetables. Carrots are one of the primary dietary sources of carotenoids. The biological activities of carotenoids in higher organisms, including their immunomodulatory activities, are well documented in most tissues but not the large intestine. The gastrointestinal barrier acts as a line of defense against the systemic invasion of pathogenic bacteria, especially at the colonic level.