2020 journal article

Transcription of intragenic CpG islands influences spatiotemporal host gene pre-mRNA processing

NUCLEIC ACIDS RESEARCH, 48(15), 8349–8359.

By: S. Amante*, B. Montibus*, M. Cowley*, N. Barkas*, J. Setiadi*, H. Saadeh*, J. Giemza*, S. Contreras-Castillo* ...

MeSH headings : Animals; Cell Differentiation / genetics; Chromatin / genetics; CpG Islands / genetics; DNA Methylation / genetics; Epigenesis, Genetic; Genome / genetics; Histone Code / genetics; Humans; Promoter Regions, Genetic; Protein Processing, Post-Translational / genetics; Pseudogenes / genetics; RNA Precursors / genetics; RNA Precursors / metabolism; Transcription, Genetic
TL;DR: It is suggested that iCGI transcription, rather than H3K36me3 or DNA methylation, interfere with host gene transcription and pre-mRNA processing genomewide and contributes to the spatiotemporal diversification of both the transcriptome and proteome. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: October 19, 2020

Abstract