Transcription of intragenic CpG islands influences spatiotemporal host gene pre-mRNA processing
NUCLEIC ACIDS RESEARCH, 48(15), 8349–8359.
MeSH headings : Animals; Cell Differentiation / genetics; Chromatin / genetics; CpG Islands / genetics; DNA Methylation / genetics; Epigenesis, Genetic; Genome / genetics; Histone Code / genetics; Humans; Promoter Regions, Genetic; Protein Processing, Post-Translational / genetics; Pseudogenes / genetics; RNA Precursors / genetics; RNA Precursors / metabolism; Transcription, Genetic
TL;DR:
It is suggested that iCGI transcription, rather than H3K36me3 or DNA methylation, interfere with host gene transcription and pre-mRNA processing genomewide and contributes to the spatiotemporal diversification of both the transcriptome and proteome.
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UN Sustainable Development Goal Categories
14. Life Below Water
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