BMAA and MCLR Interact to Modulate Behavior and Exacerbate Molecular Changes Related to Neurodegeneration in Larval Zebrafish
Toxicological Sciences, 179(2), 251–261.
author keywords: cyanotoxins; mixtures; zebrafish; behavior; proteomics
MeSH headings : Amino Acids, Diamino / toxicity; Animals; Cyanobacteria Toxins; Larva; Proteomics; Zebrafish
TL;DR:
This study evaluates the neurotoxic effects of a mixture of two co-occurring cyanotoxins, β-methylamino-L-alanine (BMAA) and microcystin leucine and arginine (MCLR), using the larval zebrafish model to reveal that BMAA and MCLR interact in vivo to enhance neurotoxicity.
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