2021 journal article

Association of Simulated COVID-19 Vaccination and Nonpharmaceutical Interventions With Infections, Hospitalizations, and Mortality

JAMA NETWORK OPEN, 4(6).

By: M. Patel *, E. Rosenstrom n , J. Ivy n, M. Mayorga n , P. Keskinocak *, R. Boyce *, K. Hassmiller Lich *, R. Smith * ...

MeSH headings : Adult; COVID-19 / epidemiology; COVID-19 / prevention & control; COVID-19 / transmission; COVID-19 Vaccines / pharmacology; Communicable Disease Control / methods; Communicable Disease Control / organization & administration; Communicable Disease Control / statistics & numerical data; Computer Simulation; Disease Transmission, Infectious / prevention & control; Female; Hospitalization / statistics & numerical data; Humans; Male; Mass Vaccination / organization & administration; Mass Vaccination / statistics & numerical data; Mortality; North Carolina / epidemiology; Risk Assessment / methods; Risk Assessment / statistics & numerical data; SARS-CoV-2; Treatment Outcome; Vaccination Coverage / organization & administration; Vaccination Coverage / statistics & numerical data
TL;DR: Findings highlight the need for high COVID-19 vaccine coverage and continued adherence to NPIs before safely resuming many prepandemic activities. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: June 10, 2021

Key Points Question What is the association of COVID-19 vaccine efficacy and coverage scenarios with and without nonpharmaceutical interventions (NPIs) with SARS-CoV-2 infections, hospitalizations, and deaths? Findings A decision analytical model of North Carolina found that removing NPIs while vaccines were distributed resulted in substantial increases in infections, hospitalizations, and deaths. Furthermore, as NPIs were removed, higher vaccination coverage with less efficacious vaccines contributed to a larger reduction in risk of infection compared with more efficacious vaccines at lower coverage. Meaning These findings highlight the need for high COVID-19 vaccine coverage and continued adherence to NPIs before safely resuming many prepandemic activities.