2021 journal article

Preparation of substituted alkoxypyridines via directed metalation and metal-halogen exchange

ARKIVOC, 57–72.

By: I. Bori n & D. Comins n

author keywords: Alkoxypyridines; directed metalation; metal-halogen exchange; halogen dance reactions
Source: Web Of Science
Added: June 21, 2021

Several halo-substituted alkoxypyridines were prepared and subjected to directed metalation and metalhalogen exchange reactions.The studies resulted in useful methods for synthesis of numerous substituted pyridines via regioselective lithiation, magnesation and halogen dance reactions.