2021 journal article
The effect of piscidin antimicrobial peptides on the formation of Gram-negative bacterial biofilms
JOURNAL OF FISH DISEASES, 45, 99–105.
author keywords: antimicrobial peptides; biofilm; Gram-negative bacteria; Piscidin
MeSH headings : Animals; Antimicrobial Peptides; Bass; Biofilms; Escherichia coli; Fish Diseases / drug therapy
TL;DR:
Fish-derived antimicrobial peptides are an important part of the innate immune system due to their potent antimicrobial properties and were sought to determine the extent to which class I and II piscidins inhibit biofilm formation of different Gram-negative bacteria.
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UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: October 12, 2021
AbstractFish‐derived antimicrobial peptides are an important part of the innate immune system due to their potent antimicrobial properties. Piscidins are a class of antimicrobial peptides first described in hybrid striped bass (Morone chrysops x Morone saxatilis) but have also been identified in many other fish species. Previous work demonstrated the broad antimicrobial activity of piscidins against Gram‐negative and Gram‐positive bacterial species. This study sought to determine the extent to which class I (striped bass piscidin 1, white bass piscidin 1 and striped bass/white bass piscidin 3) and class II (striped bass piscidin 4 and white bass piscidin 5) piscidins inhibit biofilm formation of different Gram‐negative bacteria. In general, the class I and II piscidins demonstrate potent activity against Escherichia coli and Flavobacterium columnare biofilms. The class II piscidins showed more activity against E. coli and F. columnare isolates than did the class I piscidins. The piscidins in general were much less effective against inhibiting Aeromonas hydrophila and A. veronii biofilm growth. Only the class I piscidins showed significant growth inhibition among the Aeromonas spp. examined.