2016 journal article
Retrospective evaluation of fluid overload and relationship to outcome in critically ill dogs
JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 26(4), 578–586.
author keywords: edema; fluid balance; ICU; illness severity scoring
MeSH headings : Acute Kidney Injury / etiology; Acute Kidney Injury / veterinary; Animals; Case-Control Studies; Critical Illness; Dog Diseases / etiology; Dog Diseases / mortality; Dogs; Female; Fluid Therapy / adverse effects; Fluid Therapy / veterinary; Hospitalization; Male; Odds Ratio; Retrospective Studies
TL;DR:
Critically ill dogs are at increased risk for FO during hospitalization, and a weak but significant association exists between %FO, illness severity, and mortality.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
AbstractObjectiveTo determine if critically ill dogs have an increased risk of fluid overload (FO) during hospitalization compared to less ill dogs, and to determine if FO is associated with increased mortality during hospitalization.DesignObservational, case‐control study.SettingUniversity teaching hospital.AnimalsThirty‐four critically ill dogs and 15 comparatively healthy stable postoperative dogs with neuro‐orthopedic disease.InterventionsNone.Measurements and Main ResultsData recorded included underlying disease, body weight, and APPLEfast score at admission, single‐day and composite APPLEfull scores during hospitalization, total fluid volume administered (L), total fluid volume output (L), and outcome. Percent FO (%FO) was calculated using the equation 100 × ([fluid volume administered − fluid volume lost]/1000 mL/L) − (% dehydration at admission), with fluid volume expressed as mL/kg of baseline body weight. Critically ill dogs developed greater %FO during hospitalization compared to stable postoperative dogs (12.1 ± 11.7% vs 0.5 ± 5.2%, P = 0.001), and half (8 out of 16) of the dogs with %FO ≥ 12% died. Composite APPLEfull scores were weakly positively correlated with %FO, whereas APPLEfast and single‐day APPLEfull scores recorded at admission were not. The odds ratio for death was 1.08 for every percent increase in FO during hospitalization (95% confidence limits 1.012–1.59, P = 0.02).ConclusionsCritically ill dogs are at increased risk for FO during hospitalization, and a weak but significant association exists between %FO, illness severity, and mortality. Prospective studies are warranted to confirm the findings of this retrospective study.