author keywords: transspecies; trans-eQTL; host-pathogen interaction; symbiosis; RNA-Seq

MeSH headings : Animals; Chromosome Mapping / methods; Gene Regulatory Networks; Genetic Pleiotropy; Helminth Proteins / genetics; Helminth Proteins / metabolism; Medicago / genetics; Medicago / parasitology; Plant Proteins / genetics; Plant Proteins / metabolism; Polymorphism, Genetic; Quantitative Trait Loci; Symbiosis / genetics; Transcription Factors / genetics; Transcription Factors / metabolism; Tylenchoidea / genetics; Tylenchoidea / pathogenicity

TL;DR: An expression quantitative trait locus (eQTL) mapping-based approach to identify cause-and-effect relationships between genes from two partners engaged in an interspecific interaction is developed and applied to data from a Salmonella infection study, successfully identifying polymorphisms in the human genome affecting bacterial expression. (via Semantic Scholar)