MeSH headings : Alkaloids; Biosynthetic Pathways / genetics; Gene Expression Regulation, Plant; Nicotine; Plant Proteins / genetics; Plant Proteins / metabolism; Plants, Genetically Modified / genetics; Tobacco / genetics; Tobacco / metabolism

TL;DR: Two conclusions can be inferred from this work: (1) QPT1 gene function alone appears to be inadequate for meeting the QPT demands of the plant for primary metabolism when grown in a field environment; and (2) the complete knockout of QPT2 function is not a viable strategy for producing agronomically useful, low nicotine tobaccos. (via Semantic Scholar)