Modeling of the complex interplay among plasma physics, fluid mechanics, and aerosol dynamics is critical to providing a detailed understanding of the mechanisms responsible for particulate production from plasma–surface interaction in fusion devices. Plasma/fluid and aerosol models developed for analysis of disruption simulation experiments in the SIRENS high heat flux facility integrate the necessary mechanisms of plasma–material interaction, plasma and fluid flow, and particulate generation and transport. The model successfully predicts the size distribution of primary particulate generated in SIRENS disruption-induced material mobilization experiments.