Effects of sterilization methods on gelatin methacryloyl hydrogel properties and macrophage gene expression in vitro
Biomedical Materials.
author keywords: gelatin methacryloyl; hydrogel; sterilization; macrophage phenotype; gene expression
TL;DR:
It was found that the sterilization methods only marginally altered the hydrogel morphology, swelling behavior and elastic modulus, but significantly impacted macrophage gene expression within 48 h and over 7 d in vitro, suggesting that not only the sterility and hydrogels properties, such as material destruction and degradation caused by temperature and moisture, should be taken into consideration.
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