2022 journal article
Estimating effective connectivity in Alzheimer's disease progression: A dynamic causal modeling study
FRONTIERS IN HUMAN NEUROSCIENCE, 16.
author keywords: Alzheimer's disease (AD); mild cognitive impairment (MCI); effective connectivity; dynamic causal modeling; resting-state fMRI
TL;DR:
The dwindling connectivity accompanying AD progression on causal relationships among brain regions and the potential of EC as a loyal biomarker in AD progression are demonstrated.
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www.frontiersin.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: January 30, 2023
IntroductionAlzheimer's disease (AD) affects the whole brain from the cellular level to the entire brain network structure. The causal relationship among brain regions concerning the different AD stages is not yet investigated. This study used Dynamic Causal Modeling (DCM) method to assess effective connectivity (EC) and investigate the changes that accompany AD progression.