2023 journal article

Hypertrophic cardiomyopathy in purpose-bred cats with the A31P mutation in cardiac myosin binding protein-C


By: J. Stern n, V. Rivas n, J. Kaplan*, Y. Ueda n, M. Oldach*, E. Ontiveros*, K. Kooiker*, S. Dijk*, S. Harris*

TL;DR: The occurrence of a more severe phenotype in later generations of cats, and the occasional occurrence of HCM in wildtype cats suggests the presence of at least one gene modifier or a second causal variant in this research colony that exacerbates the HCM phenotype when inherited in combination with the A31P mutation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: September 18, 2023