2024 journal article

Photoredox Catalyzed C(sp3)–C(sp3) Coupling of α-Bromoesters and Triethylamine

The Journal of Organic Chemistry.

Source: ORCID
Added: December 22, 2023

We report a photoredox methodology for C(sp3)-C(sp3) coupling between α-bromoesters and triethylamine capable of accessing building blocks with handles for further functionalization. Mechanistic studies indicate the presence of a carbon centered radical. The achiral substrates obtained with this method have the potential to be elaborated to access enantioenriched scaffolds with increased molecular complexity.